Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease Genomics SanofiSenior Principal Scientist/Principal Scientist, Real-World Evidence & Disease GenomicsCambridge, MA$148,500–$214,500 / yearYou will operate in an agile, fast-paced environment with access to industry-leading data infrastructure, working in close collaboration with disease area experts, medical teams, and therapeutic program leads to ensure your work translates into tangible impact on patients' lives. Working alongside world-class computational and experimental scientists, you will help shape the future of drug discovery and development across Sanofi's therapeutic areas - from early indication prioritization to business development evaluation of external assets.
Senior Scientist or Principal Scientist, Targeted Proteomics Kymera TherapeuticsSenior Scientist or Principal Scientist, Targeted ProteomicsWatertown, MA$115,000–$215,000 / yearDomain leadership with cross-functional drug discovery : Highly organized, solutions-oriented scientist with the ability to manage multiple priorities simultaneously while driving innovation in targeted proteomics workflows and enabling program advancement through high-impact experimental data. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.
Scientist I / Scientist II, Computational Protein Design Generate BiomedicinesScientist I / Scientist II, Computational Protein DesignSomerville, MassachusettsThe ideal candidate combines deep structural intuition with a demonstrated ability to rapidly assess and apply protein design methods and metrics across diverse design problems, thinks in terms of reusable capabilities, benchmarks, and feedback loops across applications, and uses modern generative models and experimental readouts to guide iterative design cycles across modalities. This role sits at the intersection of machine learning, structural biology, and therapeutic development, where you will stay at the leading edge of internal and external models for de novo protein design and systematically benchmark, integrate, and apply them within tightly integrated design–build–test–learn cycles to advance our therapeutic pipeline and impact patients' lives.
Scientist: Senior Quantum Optics, Atomic Physics Scientist Nanobiosym IncScientist: Senior Quantum Optics, Atomic Physics ScientistCambridge, MAIdeal candidates will possess a PhD or equivalent experience in Experimental Physics, Optical Physics, Atomic Physics, Advanced Instrumentation, Signal to noise optimization, Electrical Engineering, or a related field with 5 years of hands-on research experience. Experience in quantum optics and atomic physics such as laser-matter interactions, single-molecule imaging, precision measurement techniques, advanced detection systems, or atomic-scale instrumentation preferred.
Scientist/Sr. Scientist, Mrna Display Zealand Pharma A/SScientist/Sr. Scientist, Mrna DisplayCambridge, MA$125,000–$170,000 / yearExperience building custom cell-free display systems from scratch strongly preferred; experience with other in vitro display technologies (e.g., ribosome display) and cell-free protein/peptide expression systems (e.g., IVTT, CFS) is a plus. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health.
Scientist/Sr. Scientist, Protein Purification Zealand Pharma A/SScientist/Sr. Scientist, Protein PurificationCambridge, MA$125,000–$170,000 / yearWorking knowledge of analytical characterization techniques, including mass spectrometry, biophysical methods (e.g., DLS, MALS, SPR, BLI, DSF), and flow cytometry, sufficient to collaborate effectively with analytical specialists. As a Scientist or Senior Scientist in Protein Purification and Analysis, you will play an important scientific role supporting discovery programs, with a primary emphasis on high-quality purification of protein-based therapeutics and their bioconjugates.
Scientist/Sr. Scientist Yeast Surface Dislay Zealand Pharma A/SScientist/Sr. Scientist Yeast Surface DislayCambridge, MA$125,000–$170,000 / yearWe offer exciting responsibilities: Execute the full yeast surface display workflow, from library construction and transformation through magnetic bead and FACS-based selections, generating antibody, VHH, affibody, constrained peptide, and other mini-protein binders. As a Scientist or Senior Scientist in Yeast Surface Display, you will play a central scientific role in our new Molecular Platform Development organization, driving antibody, VHH, and other mini-protein and binder discovery through yeast display technology.
Scientist/Sr. Scientist, Molecular Biology Zealand Pharma A/SScientist/Sr. Scientist, Molecular BiologyCambridge, MA$125,000–$170,000 / yearAs a Scientist or Senior Scientist in Molecular Biology, you will play an important scientific role in our new Molecular Platform Development organization, driving high-throughput vector design and molecular cloning in support of biologics drug discovery. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health.
Associate Scientist / Scientist I, Computational Test Development Precede Biosciences, Inc.Associate Scientist / Scientist I, Computational Test DevelopmentBoston, MA$110,000–$150,000 / yearWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3-4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Senior Scientist/Principal Scientist, Protein Science Synolo TherapeuticsSenior Scientist/Principal Scientist, Protein ScienceCambridge, MassachusettsAbout RA Capital: RA Capital Management funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. Serve as the analytical and biophysical characterization lead on cross-functional project teams, partnering closely with Biologics Discovery, Biology, CMC, and external CROs to develop characterization strategies, solve complex scientific challenges, and ensure high-quality execution.
Scientist II or Senior Scientist, Protein Analytics Alloy Therapeutics IncScientist II or Senior Scientist, Protein AnalyticsWaltham, MA$130,000–$160,000 / yearAlloy's Protein Analytics group, within the Alloy Antibody Powered Division, provides analytical support across all analytical activities, including assay development, quality control, high-throughput screening, and detailed characterization of monoclonal and multispecific antibodies, TCRs, TCR mimics, and other modalities. Deliver: Drive later-stage characterization efforts end-to-end, from experimental design through data interpretation, delivering robust stability and developability packages that inform key program decisions.
Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Antares TherapeuticsSr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology)Boston, Massachusetts$160,000–$235,000 / yearCollaborate with teams across the organization, including clinical operations and data management, to ensure biomarker assay implementation and execution, and aid in the management of biomarker samples and data. The actual salary offered will be based on a number of factors, including but not limited to the qualifications of the applicant, years of relevant experience, level of education attained, certifications or other professional licenses held, and if applicable, the location in which the applicant lives and/or from which they will be performing the job.
Scientist II/Senior Scientist, Computational Biophysics Lila Sciences IncScientist II/Senior Scientist, Computational BiophysicsCambridge, MA$140,800–$217,800 / yearThis role is one part of a broader agentic drug discovery system: computational chemistry helps judge whether agent-generated optimization strategies are chemically sensible, ML scientists build cofolding and low-data learning models, and research engineers help turn validated scientific protocols into reliable scalable infrastructure. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
Associate Scientist / Scientist I, Computational Test Development Precede Biosciences IncAssociate Scientist / Scientist I, Computational Test DevelopmentBoston, MA$110,000–$150,000 / yearWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3-4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Scientist/Senior Scientist, Assay Development - Neuroscience Biomarkers Spear Bio IncScientist/Senior Scientist, Assay Development - Neuroscience BiomarkersWoburn, MAProvide scientific leadership and translate biomarker biology into assay-design strategies by optimizing for clinically relevant molecular forms, isoforms, post-translational modifications, cleavage fragments, aggregation states, epitopes, and sample types. The successful candidate will help optimize assay strategies, identify the most relevant molecular forms and epitopes, evaluate preanalytical variables and matrix effects, interpret clinical-sample data, and troubleshoot complex assay-development challenges.
Associate Scientist/ Sr. Associate Scientist Antibody And Protein Engineering Mediar TherapeuticsAssociate Scientist/ Sr. Associate Scientist Antibody And Protein EngineeringBoston, MAThe platform and pipeline are based on an emerging class of novel targets- fibrotic mediators - that play key roles in modulating myofibroblast biology and the development of fibrosis chronically damaged organs. This position offers the opportunity to impact multiple steps of the discovery and engineering process for biotherapeutic lead generation including the expression, purification, and characterization of immunogens, panning reagents and the therapeutic candidates themselves.
LC-MS Associate Scientist/Senior Scientist NovabioassaysLC-MS Associate Scientist/Senior ScientistWoburn, MassachusettsPrefer to have hands-on experience on following instrument and software: Sciex Triple Quadruple Mass Spec with Analyst software, Thermo Orbitrap Mass Spec with Xcalibur software, Thermo Watson LIMS software, Ligand-Binding assays, Hybridization LC-Fluorescence assays, RT-qPCR . These are Associate Scientist and Senior Scientist roles in the Bioanalytical Group to help developing, qualifying/validating bioanalytical methods, and analyzing small and large molecule in different biological matrix.
Scientist-Principal Scientist, Protein Design & Structure Superluminal MedicinesScientist-Principal Scientist, Protein Design & StructureBoston, MassachusettsThe successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and drug discovery programs. D. in Biochemistry, Molecular Biology, Biophysics, or a related field with 2+ years (Scientist), 5+ years (Senior Scientist), or 8+ years (Principal Scientist) of relevant experience; or a master’s or bachelor’s degree in a related field with commensurate industry experience.
Scientist/Senior Scientist, Assay Development - Molecular Assay Chemistry and Biophysics Spear Bio IncScientist/Senior Scientist, Assay Development - Molecular Assay Chemistry and BiophysicsWoburn, MATroubleshoot assay-performance issues, including low signal, nonspecific background, limited sensitivity, poor reproducibility, matrix effects, instability, and lot-to-lot variability, using a mechanistic understanding of binding kinetics, affinity, avidity, thermodynamics, steric effects, and molecular interactions. The Scientist / Senior Scientist will design, optimize, and troubleshoot innovative protein-detection assays that integrate antibody-based recognition, nucleic-acid interactions, conjugation chemistry, reaction kinetics, and quantitative analytical methods.
Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting) Novartis AGPrincipal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)Cambridge, MA$119,700–$222,300 / yearWorks in close collaboration with clinicians and clinical development colleagues to integrate PKS insights into study design, data interpretation, and project decision‑makingModels the use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, and authoring regulatory documents. Key responsibilities:Brings strong AI and digital fluency, using enterprise tools to further strategic, scientific and operational leadership in clinical pharmacologyIdentifies, develops and implements high-value use cases where AI can materially improve clinical pharmacology planning, analyses and decision quality.