Scientist I - Cell Screening and Pharmacology, Discovery Technology Nurix Therapeutics IncScientist I - Cell Screening and Pharmacology, Discovery TechnologyBrisbane, CA$127,000–$143,000 / yearThe scientist will design, execute, and analyze cellular assays that characterize DAC activity, and will partner closely with discovery biology, conjugation chemistry, analytical biochemistry, DMPK, and automation to advance candidates from early screening. Demonstrated experience designing and setting up in vitro pharmacology studies and screening cascades; prior know-how in building screening/assay cascades in the ADC or DAC field is preferred.
Scientist 3 - Translational Medicine - OMNI - Inflammatory Bowel Disease Genentech IncScientist 3 - Translational Medicine - OMNI - Inflammatory Bowel DiseaseSouth San Francisco, CA$100,400–$186,400 / yearTechnical Expert: Proven technical expertise in benchtop techniques (flow cytometry, multiplex immunoassays, ELISA, RT-qPCR, histology) and single-cell workflows (scRNA-seq, CITE-seq). Establish and execute complex human-relevant model systems (including intestinal organoids, primary immune cell co-cultures, and air-liquid interface systems) to investigate pathway biology and therapeutic mechanisms of action.
Computational Clinical Scientist II, Clinical Bioinformatics Revolution Medicines IncComputational Clinical Scientist II, Clinical BioinformaticsRedwood City, CA$132,000–$166,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs.
Scientist II AbbVie IncScientist IISouth San Francisco, CAThe role includes designing CAR constructs, executing advanced cell-based assays and collaborating with cross-functional teams to generate high-quality data that support pipeline programs. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolutediscretion, consistent with applicable law.
Principal Scientist - Oligonucleotide Design and Chemistry Genentech IncPrincipal Scientist - Oligonucleotide Design and ChemistrySouth San Francisco, CA$143,200–$266,000 / yearScientific Leadership: Proven track record of leading scientific initiatives, mentoring team members, and driving cross-functional collaborations (evidenced by publications or patents). The Therapeutic Modalities and Technologies group in the Protein Sciences organization at Genentech is responsible for the design and generation of new therapeutic modalities that combine the engineering and analytical principles of multiple scientific disciplines.
Lead Data Scientist Snorkel AILead Data ScientistSan Francisco, CA (Hybrid)$130,000–$200,000 / yearWhether you’re looking to deepen your technical expertise, explore leadership opportunities, or learn new skills across multiple functions, you’re fully supported in building your career in an environment designed for growth, learning, and shared success. 40% : Building and maintaining Generative AI Analytics 40% : Critical-path data science projects 20% : Partnering with Engineers, PMs, DaaS operational leads, and Finance What You'll Do.
Research Scientist I/II FreenomeResearch Scientist I/IIBrisbane, California$132,050–$167,475 / yearAs a Research Scientist in Genomics, you will contribute to the program’s technical base by creating and optimizing new next-generation sequencing (NGS) assays and workflows for DNA/RNA, or to the program’s scientific base by elevating our understanding of the biological context of these assay signals in cancer. You will also work closely with computational biologists and machine learning scientists to provide biological and technical insights, and to provide new data sources to enhance ongoing computational research projects.
Scientist II - Translational Sciences Contract Pliant Therapeutics IncScientist II - Translational Sciences ContractSouth San Francisco, CA$71–$79 / hourExperience designing wet-lab assays that utilize basic cell biology laboratory procedures including cell culture, cell transfection, qRT-PCR, ELISA, flow cytometry/FACS, Western blot, fluorescent microscopy, immunofluorescence-based staining, etc. We are seeking creative, curious and collaborative individuals who dare to succeed, are committed to making an important impact on patient's lives and will help us build one Pliant!
NewResearch Scientist, All-Optical Working Memory Astera InstituteResearch Scientist, All-Optical Working MemoryAlameda, CaliforniaConviction that the brain’s internal model can be understood in full, and that getting there requires a kind of science no single academic lab can do; we’re betting on scale, deep collaboration across science and engineering, and open sharing of ideas in a full-stack environment. This work sits within Astera Neuro’s larger effort to answer the hardest and least understood questions in neuroscience: how the brain generates thoughts, intelligence, and consciousness.
Research Scientist / Engineer, Functional Ultrasound Imaging Astera InstituteResearch Scientist / Engineer, Functional Ultrasound ImagingAlameda, CaliforniaFrom implementing the imaging system and designing experiments to analyzing large-scale datasets and building functional brain atlases, you'll help create one of the world's most advanced platforms for mesoscale imaging of the primate brain. We are seeking an exceptional Research Scientist or Research Engineer to lead the development of a next-generation functional ultrasound imaging (fUSI) platform for whole-brain imaging in awake, behaving primates.
Postdoctoral Fellow - Human Genetics, Bhangale Lab Genentech IncPostdoctoral Fellow - Human Genetics, Bhangale LabSouth San Francisco, CA$110,000–$120,000 / yearThe successful candidate will work with our team to analyze human genomic data generated from large case-control cohorts in Parkinson's disease and ALS, with the goal of identifying how rare coding variants disrupt protein function and contribute to disease. You will develop and apply methods that integrate protein structural information to map disease-associated variant hotspots within known disease genes and build calibrated variant effect models that combine multiple lines of molecular evidence.
Machine Learning Researcher Capable LabsMachine Learning ResearcherSan Francisco, CaliforniaBonus: Experience or a strong project history in active learning, biological modeling in data-constrained regimes, or multimodal models spanning omics, imaging, and phenotypic data. Fine-tune and apply protein and structure models, including ESM, AlphaFold-family models, RFdiffusion, and ProteinMPNN, on in-house data to generate and optimize candidates across programs.
Senior Reliability Engineer AbbottSenior Reliability EngineerAlameda, CaliforniaOur portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. We’re focused on helping people manage their health more effectively and comfortably, with life-changing products that provide accurate data to drive better-informed decisions.
Senior Business Analyst, Product Strategy Capital One Financial CorpSenior Business Analyst, Product StrategySan Francisco, CA$101,100–$115,400 / yearCurrently has, or is in the process of obtaining one of the following with an expectation that the required degree will be obtained on or before the scheduled start date: A Bachelor's Degree in a quantitative field (Business, Finance, Accounting, Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, Computer engineering, Software engineering, Mechanical engineering, Information Systems or a related quantitative field). A Master's Degree in a quantitative field (Business, Finance, Accounting, Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, Computer Engineering, Software Engineering, Mechanical engineering, Information Systems or a related quantitative field) or an MBA with a quantitative concentration.
Senior Scientist, Oligonucleotide Chemist LGC LtdSenior Scientist, Oligonucleotide ChemistPetaluma, CAExcellent data analysis and interpretation abilities Experience with quality control procedures and GMP regulations Understanding of nucleic acid therapeutics and diagnostics applications Ability to work efficiently in a fast-paced, collaborative research environment Strong organizational skills and attention to detail Excellent written and verbal communication skills in English The typical pay range for this role is: Minimum: $93,750 Maximum: $156,250 This range represents the low and high end of the anticipated salary range for the California -based position. Core function is to act as the technical oligonucleotide chemistry lead and contribute to the development and delivery of new oligonucleotide-based technologies and applications Demonstrated ability to independently design, project plan and execute development projects.
Principal Scientist, Analytical Chemistry Revolution Medicines IncPrincipal Scientist, Analytical ChemistryRedwood City, CA$190,000–$238,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Design and implementation of discovery analytics, analytical data integration through collaboration with LabOS team, Data Sciences and Data Analytics functions to develop and implement automated high-throughput analytical methods that enhance efficiency and data quality.
Senior Scientist, Antibody Conjugation Nurix Therapeutics IncSenior Scientist, Antibody ConjugationBrisbane, CAWe are growing the team with a hands-on antibody conjugation scientist who will build this capability from the ground up by developing and validating bioconjugation chemistries that are reproducible at bench scale, sufficiently robust for transfer to automated higher-throughput synthesis workflows, and scalable for preparation campaigns supporting advanced in vivo and translational studies. This is a lab-based role for someone who wants to build a new technical capability inside an established, highly collaborative discovery organization and partner closely with medicinal chemistry, analytical chemistry, computational chemistry, protein biochemistry, and automation to move candidates from bench to study-ready material.
Scientist 2, Neuroscience Discovery & iPSC Assay Development Genentech IncScientist 2, Neuroscience Discovery & iPSC Assay DevelopmentSouth San Francisco, CA$85,500–$158,700 / yearIn this role, you will leverage human induced pluripotent stem cells (iPSCs) to generate relevant central nervous system (CNS) cell models, execute functional assays, and support disease-relevant phenotyping. Qualifications & Experience: Bachelor's degree in Cell Biology, Molecular Biology, Neuroscience, or a related field with 6+ years of laboratory experience, OR a Master's degree with 4+ years of experience in iPSC and mammalian cell culture (industry or academia).
Principal Associate Scientist - Pharmaceutical Development Genentech IncPrincipal Associate Scientist - Pharmaceutical DevelopmentSouth San Francisco, CA$92,600–$172,000 / yearAs an integrated partner within the drug development ecosystem, Global Biologics Pharmaceutical Development is dedicated to effectively developing innovative and patient-centered parenteral drug products including Formulation and Process Development and Drug Delivery Systems. Our core business is to develop safe, innovative and effective drugs using cutting edge technologies for manufacturing process (Drug Substance and Drug Product), clinical supply, formulation, device, packaging, and analytical development.
Senior Scientist II - CMC Developmental Sciences AbbVie IncSenior Scientist II - CMC Developmental SciencesSouth San Francisco, CA$167,877–$178,500 / yearOf experience required, must have 3 years: (i) performing cell line &/or cell culture development utilizing knowledge of cell/molecular biology research & signaling & tumor/immune cell interactions; (ii) performing bioreactor processes, cell culture optimization & molecular biology techniques; (iii) working with lab automation; (iv) engaging in sample prep & data analysis for Next Gen Sequencing; (v) developing novel assays by applying cell culture & molecular biology knowledge; (vi) leading scientists to perform Cell Culture Process Optimization; &. Perform on various aspects of hands-on CHO cell line development, characterization studies, cell culture process development or protein purification in a well-supported and dynamic environment to help advance novel biotherapeutics into human clinical studies.