California State UniversityAssistant Professor of Biological Sciences (Invertebrate Zoology) California State UniversityAssistant Professor of Biological Sciences (Invertebrate Zoology)Turlock, CA$7,075–$7,287Stanislaus State is not currently sponsoring faculty for H-1B work status if they are subject to the $100,000 fee established under the Presidential Proclamation: Restriction on Entry of Certain Nonimmigrant Workers issued on September 19, 2025. Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act, the annual security report (ASR), is now available for viewing at https://www.csustan.edu/annual-campus-security-report.
Forma Life SciencesSenior/Principal Scientist, Formulation Development Forma Life SciencesSenior/Principal Scientist, Formulation DevelopmentIrvine, CaliforniaDescriptionAbout Forma Life SciencesForma Life Sciences is a next-generation CDMO headquartered in Irvine, California, where molecules become medicine. Forma supports oral solid dosage programs from early clinical development through commercial manufacturing, with deep formulation expertise and cGMP manufacturing capabilities...
Wacker Chemie AGPrincipal Scientist - BioProcess Development Wacker Chemie AGPrincipal Scientist - BioProcess DevelopmentSan Diego, CA$140,000–$155,000 / yearAdobe will use this information on behalf of the owner of the Website to evaluate how users use the Website, to generate reports about website activity, and to provide the website owner with additional services relating to the usage of the Website and Internet usage. The Principal Scientist independently leads complex development programs, drives platform and technology innovation, and ensures successful technology transfer to Manufacturing and MSAT.
ParexelPrincipal Scientist I or II - Liquid Chromatography-Mass Spectrometry (LC-MS) and Open Access Instrumentation Support - FSP ParexelPrincipal Scientist I or II - Liquid Chromatography-Mass Spectrometry (LC-MS) and Open Access Instrumentation Support - FSPCaliforniaFor results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement. We are looking to fill a Principal Scientist I or II – Liquid Chromatography-Mass Spectrometry (LC-MS) and Open Access Instrumentation Support position working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients located in South San Francisco, CA.
Parexel International CorpPrincipal Scientist I or II - Liquid Chromatography-Mass Spectrometry (LC-MS) and Open Access Instrumentation Support - FSP Parexel International CorpPrincipal Scientist I or II - Liquid Chromatography-Mass Spectrometry (LC-MS) and Open Access Instrumentation Support - FSPCalifornia, CA$75,000–$100,000 / yearFor results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement. We are looking to fill a Principal Scientist I or II - Liquid Chromatography-Mass Spectrometry (LC-MS) and Open Access Instrumentation Support position working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients located in South San Francisco, CA.
Association of Zoos and AquariumsBasecamp Wildlife Care Specialist - Part Time - San Diego Zoo Association of Zoos and AquariumsBasecamp Wildlife Care Specialist - Part Time - San Diego ZooSan Diego, CAThe Wildlife Care Specialist performs all job assignments with a positive attitude that supports San Diego Zoo Wildlife Alliance''s mission and vision of saving species worldwide by uniting our expertise in wildlife care and conservation science with our dedication to inspiring passion for nature and leading the fight against extinction. Qualified applicants will be responsible for feeding and providing general care of assigned habitat and ambassador wildlife, cleaning habitat enclosures and contiguous areas, providing habitat security, assessing and optimizing wildlife welfare, and performing related work as required.
Association of Zoos and AquariumsPrimates Wildlife Care Specialist - Full Time - San Diego Zoo Association of Zoos and AquariumsPrimates Wildlife Care Specialist - Full Time - San Diego ZooSan Diego, CAThe Wildlife Care Specialist performs all job assignments with a positive attitude that supports San Diego Zoo Wildlife Alliance''s mission and vision of saving species worldwide by uniting our expertise in wildlife care and conservation science with our dedication to inspiring passion for nature and leading the fight against extinction. AZA-accredited zoos and aquariums, Related Facilities, Commercial Members, Conservation Partners and Society Partners may post free unlimited online job listings as a member benefit.
Novartis AGSenior Principal Scientist/Associate Director PK Sciences (DUAL LEVEL POSTING) Novartis AGSenior Principal Scientist/Associate Director PK Sciences (DUAL LEVEL POSTING)San Diego, CA$138,600–$257,400 / yearThe scope of the role potentially includes small molecules, biologics/therapeutic proteins, antibody drug-conjugates, radioligand therapies and/or cell therapies across major therapeutic areas in Novartis, including oncology, immunology, cardiovascular renal metabolism, neuroscience, and global health. This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs.
Novartis AGPrincipal Scientist I or II, PK Sciences Therapeutic Areas (DUAL LEVEL POSTING) Novartis AGPrincipal Scientist I or II, PK Sciences Therapeutic Areas (DUAL LEVEL POSTING)San Diego, CA$108,500–$201,500 / yearD. with relevant experience in clinical pharmacology, drug metabolism and pharmacokinetics or a related background • A minimum of 0-2 years of experience in drug discovery and/or development in a relevant environment (academia, CRO, biotech or Pharma) • 2+ years of experience preferably in a lead role overseeing ADME/DMPK project strategy, either in discovery or clinical development to be considered for Principal Scientist II • Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences • Exposure to working in a cross-functional, matrixed, project-team environment • Strong oral and written communication skills. Leadership / Novartis Behaviors in Action: • Delivers results through disciplined execution, continuous improvement, and a strong focus on value and outcomes • Demonstrates an enterprise mindset and strong ownership by prioritizing resources and decisions for maximum Novartis and patient impact • Role models Novartis leadership behaviors through visible actions, continuous self reflection, and openness to feedback • Builds trust through transparent communication, clear accountability, and consistent delivery against commitments • Brings strong AI and digital fluency, using enterprise tools to enhance insight generation, decision making, and team productivity.
RocheNewPrincipal Scientist I, Molecular Lab Research and Early Development RochePrincipal Scientist I, Molecular Lab Research and Early DevelopmentPleasanton, CaliforniaYou will prototype and optimize different sequencing assay workflows by aligning pharma project needs, designing and implementing rigorous experiments, and applying established and innovative procedures to enable end-to-end solutions; You will proactively highlight issues, troubleshoot assays, and resolve technical challenges by applying broad knowledge of molecular biology techniques and accumulated experience. The goal will be to build sequencing assays on our revolutionary Axelios Sequencing platform and translating the immense potential of our Sequencing by Expansion (SBX) technology into real-world assays that can benefit patients.
F. Hoffmann-La Roche LtdNewPrincipal Scientist I, Molecular Lab Research and Early Development F. Hoffmann-La Roche LtdPrincipal Scientist I, Molecular Lab Research and Early DevelopmentPleasanton, CA$111,000–$206,500 / yearYou will prototype and optimize different sequencing assay workflows by aligning pharma project needs, designing and implementing rigorous experiments, and applying established and innovative procedures to enable end-to-end solutions; You will proactively highlight issues, troubleshoot assays, and resolve technical challenges by applying broad knowledge of molecular biology techniques and accumulated experience. The goal will be to build sequencing assays on our revolutionary Axelios Sequencing platform and translating the immense potential of our Sequencing by Expansion (SBX) technology into real-world assays that can benefit patients.
FUJIFILM Biotechnologies USA IncR&D Principal Scientist Raw Material Characterization FUJIFILM Biotechnologies USA IncR&D Principal Scientist Raw Material CharacterizationIrvine, CA$104,313–$147,624 / yearGood Documentation Practices & Good Laboratory Practices Required Skills/Education: • PhD in Biochemical Engineering, Chemical Engineering, Analytical Chemistry, Chemistry, Biochemistry • Minimum 10 years of relevant working experience in a process development and/or technical operations setting • Proficient in Analytical Method development and optimization • Effective communication skills with external and internal customers • Able to build strong relationships • Strong background in applied chemistry • Experience managing cross-functional projects • Capable of working on complex problems of a challenging nature • Capable of independent judgment in developing methods, techniques and evaluation of criteria for obtaining results to broadly defined objectives dictated by trends in business and the current product plan • Experience in technology and process improvements • Receives minimum instructions on routine work, general instructions on new assignments • Ability to speak, write and read English fluently. • Collaborate with Quality, Product Line Management, Procurement, Manufacturing and R&D to create solutions for optimal media formulation quality and supply chain and vendor management.
Adverum Biotechnologies IncPrincipal Scientist, Downstream Process Development (Contract) - AW Adverum Biotechnologies IncPrincipal Scientist, Downstream Process Development (Contract) - AWRedwood City, CA$80–$90 / hourThe successful candidate will participate in late-stage activities including design and optimization of the process as needed using historical batch data and manufacturing needs; process characterization; and tech-transfer of downstream processes to support clinical and commercial manufacturing. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians' offices to eliminate the need for frequent ocular injections to treat these diseases.
NovartisAssociate Director/Senior Principal Scientist, PK Sciences, Therapeutic Areas (Dual Level Posting) NovartisAssociate Director/Senior Principal Scientist, PK Sciences, Therapeutic Areas (Dual Level Posting)San Diego, CaliforniaAccountability, Biopharmaceutics, Chemistry, Clinical Pharmacology, Clinical Research, Clinical Trials, Critical Capabilities, Drug Development, Drug Discovery, Due Diligence, Electronic Components, Lifesciences, Mentorship, Non-Disclosure Agreements, Patient Care, Physics, Quality Control, Scheduler, Stakeholders Management, Translational Medicine, Waterfall Model, Well-Being This position drives close interdisciplinary collaboration among the PK Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through PK science sub-teams to achieve a holistic and integrative perspective of the ADME/clinical pharmacology properties of candidates and drugs.
NeoGenomics IncPrincipal Scientist Algorithm Lead NeoGenomics IncPrincipal Scientist Algorithm LeadCARemoteArchitect and lead automated analytical validation frameworks spanning accuracy, precision, sensitivity/LOD, specificity, linearity, and robustness for SNVs, indels, CNVs, structural variants, gene fusions, and RNA‑based assays. Develop and track NGS‑based quality control metrics at the read, molecule, sample, and assay levels (e.g., coverage, uniformity, duplication/UMI yield, error rates, contamination, noise profiles) to monitor analytical performance and stability.
FUJIFILM Biotechnologies USA IncPrincipal Scientist FUJIFILM Biotechnologies USA IncPrincipal ScientistThousand Oaks, CA$150,000–$210,000 / yearThis position provides leadership within a high performing team that will provide process development assessments for potential clients, is responsible for providing strong scientific leadership and hands-on support for all aspects of technology transfer, process development and scale-up, lab scale process monitoring, and process troubleshooting, and supporting regulatory submissions as needed. This position has a strong cross-functional partnership with the Cell Therapy Business leaders, Process Engineering, Technology Transfer/New Product Introduction to ensure successful development and transfer, into the site, of all client cell therapy manufacturing processes.
Neurocrine Biosciences IncSr. Principal Scientist, Pharmacometrics Neurocrine Biosciences IncSr. Principal Scientist, PharmacometricsSan Diego, CA$156,900–$214,000 / yearThe company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis and uterine fibroids, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. Requirements: PhD, PharmD, or equivalent preferred in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Chemistry, Biochemistry, or related field with a specific focus on PK and PK/PD modeling and simulation and 5+ years of drug development experience post PhD/PharmD OR.
City of Palo Alto UtilitiesExecutive Director - Junior Museum & Zoo (JMZ) City of Palo Alto UtilitiesExecutive Director - Junior Museum & Zoo (JMZ)Palo Alto, CA$115,252.80–$172,889.60 / yearThis leadership role provides strategic oversight, operational management, and long-term planning for a dynamic and highly visible division that includes an accredited zoo, children's museum, educational programs, camps, special events, birthday parties, and community engagement initiatives. Sufficient education, training and/or work experience to demonstrate possession of the following knowledge and skills, which would typically be acquired through: Bachelors degree in a related field and five years of progressively responsible, directly related experience; or, an equivalent combination of education and experience sufficient to successfully perform the essential duties of the job such as those listed above.
Genentech IncSenior/Principal Machine Learning Scientist, Structure and Simulation (AI for Drug Discovery) Genentech IncSenior/Principal Machine Learning Scientist, Structure and Simulation (AI for Drug Discovery)South San Francisco, CA$147,800–$274,400 / yearIn this role, you will: As a Senior Scientist: • Develop novel machine learning methods to answer challenging research questions in large molecule drug discovery • Work with biological and chemical data from heterogeneous sources • Contribute to an initiative to consolidate projects in machine learning theory into a single coherent model for lab-in-the-loop drug discovery. As a Principal Scientist: • Develop novel machine learning methods to answer challenging research questions in large molecule drug discovery • Work with biological and chemical data from heterogeneous sources • Lead an initiative to consolidate projects in machine learning theory into a single coherent model for lab-in-the-loop drug discovery.
Amgen IncSenior Principal Scientist - Chemical Biology & Proximity-Based Therapeutics Amgen IncSenior Principal Scientist - Chemical Biology & Proximity-Based TherapeuticsThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Basic Qualifications: Doctorate degree in Chemical Biology, Cell Biology, Biochemistry, Pharmacology, or related field [and relevant post-doc where applicable] and 3 years chemical biology and small molecule discovery, with experience in proximity-based mechanisms, molecular glues, or related areas experience.
Amgen IncPrincipal Scientist - Immunogenicity Bioanalytical Sciences Amgen IncPrincipal Scientist - Immunogenicity Bioanalytical SciencesThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Amgen IncPrincipal Scientist - Computational Biology & Translational AI (Oncology Precision Medicine) Amgen IncPrincipal Scientist - Computational Biology & Translational AI (Oncology Precision Medicine)Thousand Oaks, CA$182,535–$211,139 / yearThis role focuses on pan-asset forward and reverse translation, designing and deploying AI-enabled analytical and agentic systems that connect preclinical, translational, and clinical data to drive mechanistic understanding, biomarker hypotheses, and development strategy across oncology programs. This role is ideal for a scientist who enjoys building AI-enabled translational systems, not just running analyses, and who can integrate clinical, biological, and multi-modal data through modern Generative and Agentic AI to drive forward and reverse translational insight and decision-grade impact.
Amgen IncSr. Principal Scientist - Project Toxicologist Amgen IncSr. Principal Scientist - Project ToxicologistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
AmgenPrincipal Scientist – Computational Biology & Translational AI (Oncology Precision Medicine) AmgenPrincipal Scientist – Computational Biology & Translational AI (Oncology Precision Medicine)Thousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. This role focuses on pan‑asset forward and reverse translation, designing and deploying AI‑enabled analytical and agentic systems that connect preclinical, translational, and clinical data to drive mechanistic understanding, biomarker hypotheses, and development strategy across oncology programs.
Amgen IncPrincipal Scientist - PKDM, Modeling and Simulation Amgen IncPrincipal Scientist - PKDM, Modeling and SimulationSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. You will work directly with other PKDM stakeholders to apply quantitative solutions in the development of novel therapeutics through various activities including target/compound evaluation, design of preclinical studies, investigation of exposure-response relationships, execution of translational strategies, and influencing clinical study design.
Cellares CorpNewSupervising Principal Scientist, Process Development Cellares CorpSupervising Principal Scientist, Process DevelopmentSouth San Francisco, CA$90,000–$210,000 / yearThe primary focus of this position is to provide organizational leadership and technical insight into the onboarding and optimization of new cell therapy processes to expand and drive continuous improvement of the Cellares platform. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
Association of Zoos and AquariumsWildlife Care Specialist Hospital Association of Zoos and AquariumsWildlife Care Specialist HospitalSan Diego, CAAZA-accredited zoos and aquariums, Related Facilities, Commercial Members, Conservation Partners and Society Partners may post free unlimited online job listings as a member benefit. Perform accurate and complete record keeping, including ICU logs, treatment sheets, ZIMS, welfare assessments, and other required reports on general health, habits, behavior, fecal output, and appetite of wildlife under care.
Johnson and JohnsonSenior Principal Scientist, Computational Multiomics, Precision Measures Johnson and JohnsonSenior Principal Scientist, Computational Multiomics, Precision MeasuresSan Diego, CAFull timePartner with Neuroscience Discovery on the evaluation of target opportunities from the perspective of cutting-edge genetics, bioinformatics, biosignatures, brain biology, and mechanism, drawing upon a combination of internal and external human data resources and integrative analytics. We are searching for a Senior Principal Scientist, Computational Multiomics, Precision Measures, to be in either Cambridge, MA; Spring House, PA; La Jolla, CA United States of America or Beerse, Antwerp, Belgium, and follows a hybrid schedule of three days in the office and two days remotely per week.
Pfizer IncSenior Principal Scientist, Pre-Formulation and Materials Science Pfizer IncSenior Principal Scientist, Pre-Formulation and Materials ScienceLa Jolla, CA$124,400–$207,400 / yearExperience in using and interpreting biophysical modeling, physicochemical (solubility & dissolution) and biological (passive, transporter mediated, efflux) transport phenomena, design, interpretation, and use of in vitro experiments, or in vivo/in vitro drug metabolism studies, and interpretation of pre-clinical exposure data for the design and selection of new small molecule drug candidates and drug delivery systems. This Senior Principal Scientist position will be a strong scientific and leadership role within the Early Formulation Science and Drug Delivery (EFS-DD) group, supporting early-stage drug and drug product design, materials science characterization and strategy, and biopharmaceutics understanding as well as early clinical drug delivery strategy of new small molecules.
Xaira TherapeuticsNewPrincipal Scientist, Functional Genomics Xaira TherapeuticsPrincipal Scientist, Functional GenomicsCaliforniaYou will work closely with AI/ML scientists, computational biologists, automation engineers, and disease biology teams to develop scalable perturbation workflows, implement new technologies, and drive high-quality data generation and experimental innovation across multiple therapeutic areas. Develop and implement advanced functional genomics technologies, including perturb-seq, CRISPRi/a, and single-cell omics workflows across complex cellular systems such as primary cells, differentiated cell types, and in vivo models.
Eikon Therapeutics IncPrincipal Scientist, Computational Chemistry Eikon Therapeutics IncPrincipal Scientist, Computational ChemistryMillbrae, CA$204,000–$223,250 / yearDeliver virtual screening workflows that leverage physics- and AI-based modeling methods involving ligand- and structure-based methods, ensemble docking, molecular dynamics, and free energy calculations. We seek a Principal Scientist in Computational Chemistry with a demonstrated ability of successfully applying in silico technologies to drive the discovery of quality lead-like molecules against hard to drug therapeutic targets.
Bristol-Myers Squibb CoPrincipal Scientist, Computational Sciences - Protein Structure Prediction and Design Bristol-Myers Squibb CoPrincipal Scientist, Computational Sciences - Protein Structure Prediction and DesignSan Diego, CA$156,890–$190,117 / yearIn this role, you will build and deploy cutting edge machine learning and structure-based methods to accelerate biologics discovery across our preclinical portfolio (antibodies, multispecifics, ADCs, and novel scaffolds) and play a pivotal role in scaling an agentic antibody design platform from prototype to a core engine of research. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Calico Life Sciences LLCPrincipal Scientist, Antibody Engineering & Rational Design Calico Life Sciences LLCPrincipal Scientist, Antibody Engineering & Rational DesignSouth San Francisco, CA$198,000–$241,000 / yearCalico's highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs. Demonstrated ability to work intimately with data scientists and ML engineers and able to articulate biological constraints (e.g., immunogenicity, manufacturability) to computational teams and interpret their in silico outputs for experimental validation.
Bristol-Myers Squibb CoPrincipal Scientist Bristol-Myers Squibb CoPrincipal ScientistSan Diego, CA$149,390–$181,023 / yearBachelor's Degree + 8+ years of academic/industry experience OR Master's Degree + 6+ years of academic/industry experience OR PhD + 4+ years of academic/industry experience in biochemistry, enzymology, or a related scientific discipline. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
Uber Technologies IncPrincipal Scientist - Lever Efficiency Uber Technologies IncPrincipal Scientist - Lever EfficiencySan Francisco, CAThis requires more than just technical brilliance in econometrics and causal inference it requires the grit to challenge existing assumptions and the leadership to align dozens of independent science teams toward a single source of truth. Communicate with Impact synthesizing complex causal findings into clear compelling narratives for senior business leaders and executive audiences to drive investment decisions.
Lila SciencesNewSenior / Principal Scientist, AI for Protein Engineering Lila SciencesSenior / Principal Scientist, AI for Protein EngineeringSan Francisco, CaliforniaWithin Life Sciences AI (LSAI), the AI for Protein Engineering team develops and uses the generative and predictive models that drive Lila's biomolecule design programs from in silico hypothesis to wet-lab validated lead. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
Envista DentistryPrincipal Scientist Envista DentistryPrincipal ScientistPomona, CaliforniaEnvista will consider unsolicited referrals and/or resumes submitted by vendors such as search firms, staffing agencies, professional recruiters, fee-based referral services and recruiting agencies (Agency) to have been referred by the Agency free of charge and Envista will not pay a fee for any placement resulting from the receipt such unsolicited resumes. An Agency must obtain advance written approval from Envista's internal Talent Acquisition or Human Resources team to submit resumes, and then only in conjunction with a valid fully-executed contract approved by the Global Talent Acquisition leader and in response to a specific job opening.
Genentech IncNewPrincipal Scientist - Translational Medicine (Tumor Microenvironment) Genentech IncPrincipal Scientist - Translational Medicine (Tumor Microenvironment)South San Francisco, CA$141,500–$262,900 / yearDesign and implement translational research plans leveraging clinical samples, multi-omic profiling, spatial biology, single-cell technologies, functional immune assays, and emerging AI-enabled analytical approaches, including agentic AI tools, to uncover mechanisms of response, resistance, tumor microenvironment interactions, and disease evolution. This role also includes developing and leading hypothesis-driven translational research focused on identifying and developing novel biomarkers of therapeutic response and resistance, as well as uncovering disease-specific mechanistic insights.
Merck & Co IncPrincipal Scientist, Protein Engineering Merck & Co IncPrincipal Scientist, Protein EngineeringSouth San Francisco, CA$176,200–$277,300 / yearPhD in Protein Engineering, Biochemistry, Biology, Biophysics, Biotechnology, Bioengineering, Immunology, Pharmaceutical Sciences, Chemistry, Computational Protein Design, or related STEM field with 8+ years of applied experience, or an MS and 10+ year of applied experience or a B.S. and 14+ years of applied experience. Work closely with HT protein engineering and computational protein engineers to integrate augmented designs and computational approaches toward accelerated derisking and optimization of biologics for best-in-class and first-in-class therapeutics.
Merck & Co IncAssociate Principal Scientist, In Vivo Pharmacology Merck & Co IncAssociate Principal Scientist, In Vivo PharmacologySouth San Francisco, CA$159,600–$251,200 / yearCollaborate with cross-functional groups (Biology, Med Chem, DMPK, Safety, etc.) to enable a comprehensive pharmacology strategy that enables robust assessment of target engagement, in vitro/in vivo correlation, PK/PD relationship, and human dose projection. Required Experience and Skills: Quantitative and translational pharmacology expertise with a solid understanding of key pharmacology concepts including target occupancy, in vitro/in vivo correlation, PK/PD, translational biomarker, and methods for human does projection.
Merck & Co IncAssociate Principal Scientist, Respiratory Discovery Merck & Co IncAssociate Principal Scientist, Respiratory DiscoverySouth San Francisco, CA$159,600–$251,200 / yearThis role is suited for a highly independent scientist who can design and execute complex studies, generate high-quality scientific insights, and contribute effectively to cross-functional project teams within a matrixed drug discovery environment.m. Required Skills: Drug Target Identification, Ex Vivo, In Vitro Studies, Program Leadership, Pulmonary Disorders, Respiratory Diseases Prevention, Respiratory Diseases Treatment, Respiratory Pharmacology, Target Validation.
Merck & Co IncAssociate Principal Scientist, Discovery Oncology Merck & Co IncAssociate Principal Scientist, Discovery OncologySouth San Francisco, CA$159,600–$251,200 / yearRequired Skills: Biochemistry, Cancer Cell Biology, Cancer Research, Cell Biology, Immuno-Oncology, In Vitro Biology, In Vitro Research, In Vitro Studies, Molecular Biology, Oncology, Tumor Biology. Extensive hands-on in vitro experience designing, executing, and analyzing multi-color flow cytometry and mechanistic cell-based assays (e.g., viability/cytotoxicity, cell cycle, signaling, and immune response readouts).
United States ArmyNURSING (OCCUPATIONAL HEALTH) United States ArmyNURSING (OCCUPATIONAL HEALTH)Rancho Cordova, CA$99,218–$128,987 / yearSpecialized experience may have been demonstrated by performing duties such as: Planning, developing, reviewing and analyzing, and maintaining a comprehensive Occupational Health Program; Experience in formulating, analyzing, revising, and implementing policies, procedures and best practices in order to accomplish program goals and objectives in accordance with Federal, State and local laws, such as, Occupational Safety Health Administration Act of 1970 - OSHA, Federal Employees Compensation Act, Department of Labor, Department of Transportation and the Nuclear Regulatory Commission statutes, and DoD guidance; Experience in determining if personnel are physically, mentally and psychologically suited for work in field operations and the industrial workplace; Experienced in managing job-related hazards, such as chemical, biological, radiological, nuclear, and explosive hazards. NURSING (OCCUPATIONAL HEALTH), GS-0610-12: Must have at least one year of specialized experience, equivalent to at least the GS-11 level, or equivalent pay band in other pay systems in the Federal government, have at least least two years of specialized experience with understanding of the principles and concepts defined by a practical knowledge of health services activities such as, administration, managed care, human resource management, logistics management, patient administration, budgetary and fiscal management, medical manpower, medical facility management, biometrics, medical recruiting, or aeromedical evacuation and have at least 1 year of specialized experience in performing the occupational health programs.
SonoThera IncSenior/Principal Scientist SonoThera IncSenior/Principal ScientistSouth San Francisco, CA$150,000–$206,000 / yearTechnical Requirements & Skills: Demonstrated success in developing potent and safe gene therapy payloads for both viral and non-viral delivery, evidenced by first authorship in peer-reviewed publications, patents, and presentations at major international gene therapy conferences. Work in close connection with project management team and manage vector development activities, leveraging advanced project management tools such as SmartSheet to ensure accurate timelines, resource allocation, and milestone delivery.
Envista Holdings CorpPrincipal Scientist Envista Holdings CorpPrincipal ScientistPomona, CA$156,100–$190,700 / yearEnvista will consider unsolicited referrals and/or resumes submitted by vendors such as search firms, staffing agencies, professional recruiters, fee-based referral services and recruiting agencies (Agency) to have been referred by the Agency free of charge and Envista will not pay a fee for any placement resulting from the receipt such unsolicited resumes. An Agency must obtain advance written approval from Envista's internal Talent Acquisition or Human Resources team to submit resumes, and then only in conjunction with a valid fully-executed contract approved by the Global Talent Acquisition leader and in response to a specific job opening.
Nkarta, Inc.Principal Scientist, Bioinformatics Nkarta, Inc.Principal Scientist, BioinformaticsSouth San Francisco, CA$180,000–$215,000 / yearA central focus of this role is to drive and execute on Nkarta's strategy for single-cell and spatial transcriptomics, leveraging scRNA-seq, spatial, and functional genomics approaches to drive translational insights, biomarker development, and clinical decision-making in early development. Nkarta is a publicly traded (Nasdaq symbol NKTX), clinical-stage biotechnology company headquartered in South San Francisco, focused on advancing the development of allogeneic, off-the-shelf natural killer (NK) cell therapies to treat autoimmune disease.
CytokineticsPrincipal Scientist, Translational Genetics CytokineticsPrincipal Scientist, Translational GeneticsSouth San Francisco, CaliforniaCytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. Analyze and integrate multi-omics data (genomics, transcriptomics, proteomics, metabolomics) to identify causal variants and pathways associated with cardiovascular diseases.
ADOBE IncPrincipal Scientist - Agentic Product ADOBE IncPrincipal Scientist - Agentic ProductSan Jose, CA$248,900–$360,500 / yearDeep, hands-on expertise with large language models - including practical fluency with LLM APIs, prompt engineering at scale, fine-tuning and RLHF concepts, context window management, retrieval-augmented generation, and the operational realities of running LLM-backed systems in production. Adobe's industry-leading offerings including Adobe Acrobat Studio, Adobe Express, Adobe Firefly, Creative Cloud, Adobe Experience Platform, Adobe Experience Manager, and GenStudio enable people and businesses to turn ideas into impact, powered by AI and driven by human ingenuity.
Lila Sciences IncSenior / Principal Scientist, Foundation Models for life Sciences Lila Sciences IncSenior / Principal Scientist, Foundation Models for life SciencesSan Francisco, CA$288,000–$480,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
ADOBE IncPrincipal Scientist, Generation Data Architect (Image & Video & Audio) ADOBE IncPrincipal Scientist, Generation Data Architect (Image & Video & Audio)San Jose, CA$268,000–$388,000 / yearAdobe's industry-leading offerings including Adobe Acrobat Studio, Adobe Express, Adobe Firefly, Creative Cloud, Adobe Experience Platform, Adobe Experience Manager, and GenStudio enable people and businesses to turn ideas into impact, powered by AI and driven by human ingenuity. Your work will directly impact how Firefly understands concepts like style, motion, and real-world variation-helping deliver more realistic, controllable, and useful creative tools to millions of users.