Director, Clinical Development CRISPR Therapeutics AGDirector, Clinical DevelopmentSouth Boston, MA$210,000–$225,000 / yearThe Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY (exagamglogene autotemcel [exa-cel]), the worlds first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. Familiarity with ICH, GCP, and relevant regulatory requirements, and strong analytical and strategic thinking skills, experience with interacting with medical monitors, development operations (preclinical, clinical operations, regulatory affairs, Quality Assurance) and clinical investigators.
Regional Sales Director - New England GSK plcRegional Sales Director - New EnglandBoston, MARemote$186,750–$311,250 / yearThe Regional Sales Director provides field leadership across a complex and matrixed commercial environment, partnering with sales leadership, commercial operations, marketing, market access, account management, and other cross-functional partners. Proven success working within highly matrixed organizations and leading coordinated execution across sales, market access, reimbursement, organized provider accounts, medical affairs, and marketing functions.
Director, Global Scientific Communications, Hematology AstraZeneca PlcDirector, Global Scientific Communications, HematologyBoston, MARemote$230,870–$260,678 / yearAlexion, AstraZeneca Rare Disease is seeking a Director, Global Scientific Communications, Hematology to lead global scientific communications strategy, publication planning, and medical education for a high-impact Hematology portfolio across key lifecycle stages in Boston, one of the world's most competitive life sciences markets. Unlike many smaller biotech environments where communications leaders may be limited by a single asset, narrow funding horizon, or build-from-scratch infrastructure, this role offers strategic ownership, enterprise resources, global reach, mature publication governance, and the opportunity to contribute across an established rare disease platform.
Associate Director, US HCP Peer-to-Peer Marketing, GMG & NMOSD, Rare Neurology AstraZeneca PlcAssociate Director, US HCP Peer-to-Peer Marketing, GMG & NMOSD, Rare NeurologyBoston, MA$151,081.60–$226,622.40 / yearThis role serves as the enterprise P2P lead across two highly competitive rare neurology markets, partnering closely with the gMG and NMOSD brand marketing teams, Thought Leader Liaison (TLL) team, Field Sales, and Medical Affairs to educate, engage, and enable HCPs to appropriately identify, diagnose, and treat patients with Alexion's rare neurology portfolio. Advisory Board Strategy & Execution: Leading the planning and execution of advisory boards across gMG and NMOD to generate actionable insights, including defining objectives, developing discussion guides, identifying and engaging participants in partnership with Medical and TLLs, and translating insights into brand strategies.
Clinical Research, Senior Principal Scientist (Director), Oncology Lantheus Holdings IncClinical Research, Senior Principal Scientist (Director), OncologyBedford, MA$172,000–$287,000 / yearProvide scientific leadership to cross-functional teams spanning Clinical Operations, Imaging Sciences and Operations, Biostatistics, Regulatory Affairs, Medical Affairs, Pharmacovigilance, CMC, Translational Sciences and external partners. The role shapes clinical research strategy and leads the scientific design, execution, interpretation and communication of company-sponsored clinical research, with particular emphasis on diagnostic imaging, radiopharmaceuticals and molecular imaging.
Executive Director, State Government Affairs Stoke Therapeutics, Inc.Executive Director, State Government AffairsBedford, MA$278,000–$322,000 / yearPosition Purpose: The Executive Director, State Government Affairs will lead Stoke Therapeutics' state-level government affairs strategy across priority U.S. states, advancing policy environments that support people living with Dravet syndrome and other severe genetic diseases, access to innovative RNA medicines, and potential future access to zorevunersen, if approved. Monitor, analyze, and influence state legislative, executive, regulatory, and political developments affecting rare disease, Dravet syndrome, genetic testing, pediatric neurology, Medicaid, commercial insurance, and access to innovative therapies; provide timely, actionable guidance on risks and opportunities.
Associate Director, MLR Governance Amylyx Pharmaceuticals IncAssociate Director, MLR GovernanceCambridge, MARemote$184,000–$207,000 / yearThis highly cross-functional role will chair the once-weekly MLR review meeting and serve as the operational owner of the review process, helping ensure that materials developed by Marketing and other content-generating teams are reviewed, approved, documented, and distributed in a compliant, efficient, and audit-ready manner. Partner with Medical, Legal, Regulatory, Compliance, Commercial, Market Access, Patient Services, agencies, and other content-generating teams to support timely, high-quality review of materials intended for healthcare professionals, patients living with PBH, caregivers, and other external stakeholders.
NewGlobal Clinical Head (Pulmonologist)- Executive Director AstraZeneca PlcGlobal Clinical Head (Pulmonologist)- Executive DirectorCambridge, MA$331,873.60–$497,810.40 / yearAccountabilities: The Global Clinical Head (GCH) will have overall clinical leadership of one or more global products in the Infectious Disease pipeline specifically related to the prevention of infections in patients with chronic respiratory diseases. The GCH is also responsible for medical/scientific strategies for the clinical components of the Target Product Profile (TPP), Clinical Development Plan (CDP), and regulatory documents (e.g., briefing documents, CTD/BLA, core labelling texts).
Director of Product Marketing, PLM Pilot Thomas LogisticsDirector of Product Marketing, PLMMassachusettsRemoteThis is a high-impact individual contributor role for someone who combines deep PLM domain expertise with the strategic marketing instincts to influence how enterprise buyers evaluate, adopt, and expand their use of PLM technology — and who embraces emerging tools and approaches, including AI, to continuously sharpen how they research, create, and go to market. Working alongside teammates across the product marketing organization, you’ll help craft cross-portfolio solution stories that connect PLM to CAD, ALM, SLM, and IoT — translating integrated product engineering into compelling value propositions for discrete manufacturers.
NewAssociate Director, Clinical Scientist, Ophthalmology Merck & Co IncAssociate Director, Clinical Scientist, OphthalmologyBoston, MA$142,400–$224,100 / yearRequired Skills: Clinical Development, Clinical Research, Clinical Sciences, Clinical Trial Documentation, Clinical Trials Monitoring, Good Clinical Practice (GCP), Life Science, Pharmaceutical Sciences, Strategic Thinking, Study Design. Under the direction of the Program Lead, you will collaborate with global cross functional team members including clinical directors and study managers to lead/support clinical trial scientific activities.
Associate Director, Device Lead GSK plcAssociate Director, Device LeadWaltham, MA$142,725–$237,875 / yearThese responsibilities include some of the following: Be the SPOC technical SME interface between Device/Component suppliers and GSK MSAT site teams - providing device-related technical management to MSAT where required for business improvement projects and risk management activities, represent MSAT at supplier technical and project meetings. Drive innovation through the introduction of new and novel device technologies and/or ways of working and champion business cases for sustainable manufacturing technology implementation or other strategic projects including those related to quality by design, design for manufacturing, product and process understanding, design control, and digital data management, and analytical competency.
Associate Director Clinical Scientist Immunology Cell Therapy AstraZeneca PlcAssociate Director Clinical Scientist Immunology Cell TherapyCambridge, MA$142,171.20–$213,256.80 / yearStudy level: Serving as the clinical science resource for assigned studies (and in some instances as the Study Clinical Lead); supporting/leading development of Clinical Study Protocols (CSPs), informed consent forms (ICFs), and electronic data capture (EDC) database specifications in line with the approved CDP and target product profile; supporting ongoing clinical data review and interpretation at study and program level with input from the study/program physician; contributing to development of quality metrics and data review plans for assigned studies; support and contribute to medical monitoring of trials; supporting the compilation and interpretation of data for dose‑escalation/safety review committees; supporting protocol amendments and other strategic documents; and supporting review of the Clinical Study Report. ESCR and external engagement: Co‑leading/supporting ESCR strategy and implementation for the program; serving as the interface between the GPT and external clinical research; supporting investigator/site relationships for site selection and study start‑up; co‑leading/supporting clinical proposal reviews, protocol reviews and scientific oversight for academic basket/umbrella and ESCR studies; identifying and managing ESCR portfolio risks and escalating quality issues through appropriate channels; supporting representation of the project internally and externally with key experts and partners and contributing to alliance development.
Clinical Research & Development Associate Director Myositis/Immunology AstraZeneca PlcClinical Research & Development Associate Director Myositis/ImmunologyCambridge, MA$142,171.20–$213,256.80 / yearStudy level: Serving as the clinical science resource for assigned studies (and in some instances as the Study Clinical Lead); supporting/leading development of Clinical Study Protocols (CSPs), informed consent forms (ICFs), and electronic data capture (EDC) database specifications in line with the approved CDP and target product profile; supporting ongoing clinical data review and interpretation at study and program level with input from the study/program physician; contributing to development of quality metrics and data review plans for assigned studies; support and contribute to medical monitoring of trials; supporting the compilation and interpretation of data for dose‑escalation/safety review committees; supporting protocol amendments and other strategic documents; and supporting review of the Clinical Study Report. ESCR and external engagement: Co‑leading/supporting ESCR strategy and implementation for the program; serving as the interface between the GPT and external clinical research; supporting investigator/site relationships for site selection and study start‑up; co‑leading/supporting clinical proposal reviews, protocol reviews and scientific oversight for academic basket/umbrella and ESCR studies; identifying and managing ESCR portfolio risks and escalating quality issues through appropriate channels; supporting representation of the project internally and externally with key experts and partners and contributing to alliance development.
Associate Director Clinical Scientist, Immunology Cell Therapy AstraZeneca PlcAssociate Director Clinical Scientist, Immunology Cell TherapyCambridge, MA$142,171.20–$213,256.80 / yearStudy level: Serving as the clinical science resource for assigned studies (and in some instances as the Study Clinical Lead); supporting/leading development of Clinical Study Protocols (CSPs), informed consent forms (ICFs), and electronic data capture (EDC) database specifications in line with the approved CDP and target product profile; supporting ongoing clinical data review and interpretation at study and program level with input from the study/program physician; contributing to development of quality metrics and data review plans for assigned studies; support and contribute to medical monitoring of trials; supporting the compilation and interpretation of data for dose‑escalation/safety review committees; supporting protocol amendments and other strategic documents; and supporting review of the Clinical Study Report. ESCR and external engagement: Co‑leading/supporting ESCR strategy and implementation for the program; serving as the interface between the GPT and external clinical research; supporting investigator/site relationships for site selection and study start‑up; co‑leading/supporting clinical proposal reviews, protocol reviews and scientific oversight for academic basket/umbrella and ESCR studies; identifying and managing ESCR portfolio risks and escalating quality issues through appropriate channels; supporting representation of the project internally and externally with key experts and partners and contributing to alliance development.
Director, Clinical Scientist - Immunology AstraZeneca PlcDirector, Clinical Scientist - ImmunologyCambridge, MA$203,709.60–$305,564.40 / yearConduct AESI reviews and trending (these include CRS, neurotoxicity/ICANS, infections, IEC-HS, IEC-associated colitis, and new malignancies), prepare SRC, IDMC, and DMC safety packets, and flag emerging signals promptly with proposed next steps, bringing medical-judgement items to the Study Physician. Draft and review clinical sections of regulatory documents and responses, including HA interactions, briefing books, IND and annual reports, PIPs, and safety updates, ensuring SLMOP-driven surveillance outputs are reflected accurately and aligned with GCP, ICH, FDA, and EMA expectations.
Director/Senior Director, Science Click TherapeuticsDirector/Senior Director, ScienceBoston, MA$165,000–$195,000 / yearClick Therapeutics may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Consistently named a best place to work, Click fosters an inclusive, diverse workforce of innovators, clinicians, scientists, researchers, designers, technologists, engineers and more, united in a common mission to provide patients everywhere access to safe and effective prescription digital therapeutics.
NewDirector of Clinical Affairs, School of Medicine Tufts UniversityDirector of Clinical Affairs, School of MedicineBoston, MassachusettsReporting to the Vice Dean, Academic Affairs, the Director develops and sustains partnerships with teaching hospitals, community health centers, physician practices, and other clinical organizations to support high-quality educational experiences and advance the School's educational mission. This highly visible leadership role requires exceptional relationship management, strategic planning, and organizational skills, along with the ability to influence outcomes, navigate complex environments, and drive continuous improvement across clinical education partnerships and operations.
Senior or Executive Director, AI Strategy & Applications Kymera Therapeutics IncSenior or Executive Director, AI Strategy & ApplicationsWatertown, MA$235,000–$335,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Own evaluation, selection, and administration of AI platforms (LLM tools, AI-assisted coding tools, scientific AI applications) across the enterprise, partnering with leadership to design and implement AI strategy for their functions.
Nurse Manager Casa EsperanzaNurse ManagerTewksbury, Massachusetts$125,000–$130,000 / yearThrough Casa’s ITS Model (individualized and integrated care model), the Nurse Manager will work collaboratively with our Medical Director, NP Medical Director Designee (FNP), and our PMHNP, to lead our nursing team, provide the highest quality patient care, implement doctor’s orders, monitor specified medication/refills, monitor and record vital signs as needed, and maintain thorough and timely medical/nursing records. Casa Esperanza’s Conexiones program is a 32-bed facility that provides Individualized Treatment Services Program (ITS) which delivers integrated acute treatment services and withdrawal management and clinical stabilization services (CSS) to adults struggling with co-occurring substance use and mental health treatment needs.
Nurse Manager Opportunities to Join Our Amazing TeamNurse ManagerTewksbury, Massachusetts$125,000–$130,000 / yearThrough Casa’s ITS Model (individualized and integrated care model), the Nurse Manager will work collaboratively with our Medical Director, NP Medical Director Designee (FNP), and our PMHNP, to lead our nursing team, provide the highest quality patient care, implement doctor’s orders, monitor specified medication/refills, monitor and record vital signs as needed, and maintain thorough and timely medical/nursing records. Casa Esperanza’s Conexiones program is a 32-bed facility that provides Individualized Treatment Services Program (ITS) which delivers integrated acute treatment services and withdrawal management and clinical stabilization services (CSS) to adults struggling with co-occurring substance use and mental health treatment needs.