Scientist / Senior Scientist, Protein Engineering Kodiak Sciences IncScientist / Senior Scientist, Protein EngineeringPalo Alto, CAOur Antibody Biopolymer Conjugate Drug (ABCD) platform integrates protein and peptide engineering & discovery, polymer chemistry, small molecule drug discovery, bioconjugation, and drug delivery technologies to address high-prevalence ophthalmic diseases. D. in Medicinal Chemistry, Organic Chemistry, Chemical Biology, Biochemistry, or a related field, with either (i) 0-3 years of relevant postdoctoral experience and at least one first-author publication in a high-impact, peer-reviewed journal (preferred), or (ii) 3+ years of relevant industry experience.
PRINCIPAL SCIENTIST- (Protein Immunotherapy) Scripps ResearchPRINCIPAL SCIENTIST- (Protein Immunotherapy)San Diego, CA$120,000–$150,000 / yearPart timeLeveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while re-investing in further innovative research. Design and execute project plans focused on comprehensive immune profiling using flow cytometry, including signaling pathway characterization, xenograft-derived cell processing, and functional assays such as cytotoxicity, proliferation, activation, and survival assays.
Platform Scientist: Comparative Protein Evolution Arcadia Science LLCPlatform Scientist: Comparative Protein EvolutionEmeryville, CA$130,000–$180,000 / yearThese contributions will be instrumental in developing new computational tools, validating existing tools, testing novel hypotheses, identifying knowledge and dataset gaps, and driving the creation of new computational approaches for studying protein evolution at Arcadia. The Platform Scientist will develop computational approaches to study how natural protein variation arises and is shaped over macroevolutionary timescales, integrating sequence, structure, and function to ask how, and why, proteins differ across the tree of life.
Scientist - Protein Biochemist AmgenScientist - Protein BiochemistThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Responsibilities: Protein Biochemistry: Be actively involved in the design and execution of molecular cloning and protein expression strategies with the Amgen Discovery Protein Science team or CROs; design and execute purification strategies to support the structure determination of drug targets.
Associate Protein Chemist Eurofins Scientific SEAssociate Protein ChemistSan Diego, CA$52,000–$57,000 / yearEurofins Lancaster Laboratories Professional Scientific Services (PSS) is a global, award-winning insourcing solution that places our people at our clients' site dedicated to running and managing laboratory services while eliminating headcount, co-employment and project-management worries. We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client's quality systems and equipment.
Platform Scientist: Comparative Protein Evolution Arcadia SciencePlatform Scientist: Comparative Protein EvolutionEmeryville, CA$130,000–$180,000 / yearThese contributions will be instrumental in developing new computational tools, validating existing tools, testing novel hypotheses, identifying knowledge and dataset gaps, and driving the creation of new computational approaches for studying protein evolution at Arcadia. The Platform Scientist will develop computational approaches to study how natural protein variation arises and is shaped over macroevolutionary timescales, integrating sequence, structure, and function to ask how, and why, proteins differ across the tree of life.
Senior Scientist-Principal Scientist-Antibody Protein Engineering Prellis Biologics IncSenior Scientist-Principal Scientist-Antibody Protein EngineeringBerkeley, CACore activities:Reformat biologics across modalities (scFv, scFv-Fc, minibodies, Fab, VHH, Fc fusions, albumin fusions, TCRm) and assemble multispecifics (knob-in-hole, CrossMab, DVD-Ig, common LC, DARTs). We are committed to empowering our pharmaceutical partners with access to the most promising fully human antibody candidates rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.
Senior Scientist II, Biophysics And Protein Sciences Revolution Medicines, Inc.Senior Scientist II, Biophysics And Protein SciencesRedwood City, CA$170,000–$212,000 / yearDesign, execute, and interpret quantitative biophysical experiments to characterize protein quality, molecular interactions, binding mechanisms, kinetics, thermodynamics, stability, oligomerization, and higher-order complex formation, integrating these data to drive project decisions. The successful candidate will provide scientific leadership in selecting and integrating the most appropriate biophysical approaches to address key discovery questions, including the characterization of weak, transient, and cooperative protein interactions relevant to our molecular glue discovery platform.
Research Associate I (Protein Science & Analytics) The EVERY CompanyResearch Associate I (Protein Science & Analytics)San Francisco, CA$75,000–$85,000 / yearEVERY's goal is to have a workplace that enables productivity and meaningful work for individuals from all backgrounds, experiences, and lifestyles, allowing all employees to feel comfortable being their true, authentic selves at work. Support protein characterization workflows through lab-scale protein powder generation involving bench-scale downstream processing unit operations (microfiltration, ultrafiltration, diafiltration).
Senior Scientist II, Biophysics and Protein Sciences Revolution MedicinesSenior Scientist II, Biophysics and Protein SciencesRedwood City, CaliforniaDesign, execute, and interpret quantitative biophysical experiments to characterize protein quality, molecular interactions, binding mechanisms, kinetics, thermodynamics, stability, oligomerization, and higher-order complex formation, integrating these data to drive project decisions. The successful candidate will provide scientific leadership in selecting and integrating the most appropriate biophysical approaches to address key discovery questions, including the characterization of weak, transient, and cooperative protein interactions relevant to our molecular glue discovery platform.
Senior Scientist II, Biophysics and Protein Sciences Revolution Medicines IncSenior Scientist II, Biophysics and Protein SciencesRedwood City, CA$170,000–$212,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Design, execute, and interpret quantitative biophysical experiments to characterize protein quality, molecular interactions, binding mechanisms, kinetics, thermodynamics, stability, oligomerization, and higher-order complex formation, integrating these data to drive project decisions.
Scientist II, ML - Guided Protein Design Evaluation ProfluentScientist II, ML - Guided Protein Design EvaluationEmeryville, CA$147,000–$180,000 / yearYou will help scope targets and assays, partner with ML scientists to define what "model-ready" data looks like for each campaign, set and enforce assay readiness and QC expectations, and close the Design Build Test Learn loop by tracking how each dataset impacts model performance. You'll collaborate with ML and Protein Design scientists to develop experimental designs, review assay protocols, troubleshoot data quality issues with internal teams and CROs, and work closely with ML scientists to understand how data is used in model training.
RESEARCH ASSISTANT II - Pharmacology The Scripps Research InstituteRESEARCH ASSISTANT II - PharmacologySan Diego, CA$70,304–$77,000 / yearLeveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. Calibr-Skaggs' drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age-related and degenerative diseases.
NewProcess Development Senior Scientist - Pre-Pivotal Drug Product Technologies AmgenProcess Development Senior Scientist - Pre-Pivotal Drug Product TechnologiesThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The role involves designing and developing liquid and lyophilized formulations; evaluating critical quality attributes (CQAs); establishing robust, scalable fill/finish processes for complex biologic drug products; and authoring and supporting high quality regulatory submissions.
NewProcess Development Senior Associate AmgenProcess Development Senior AssociateThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Scientist/Sr Scientist - Protein Production and Purification Kodiak Sciences IncScientist/Sr Scientist - Protein Production and PurificationPalo Alto, CADesign, execute, and optimize recombinant protein expression workflows for a broad range of recombinant protein targets, including antibodies, therapeutic proteins, enzymes, and research reagents, using transient mammalian expression systems (e.g., HEK293, CHO) and bacterial expression platforms. Perform biochemical and biophysical characterization of recombinant proteins using SDS-PAGE, SEC, DLS, mass photometry, isoelectric focusing (IEF), and complementary analytical techniques to evaluate protein quality, purity, identity, aggregation, stability, and other critical quality attributes.
Senior Field Application Scientist, Protein XI Meso Scale Diagnostics LLCSenior Field Application Scientist, Protein XISan Francisco, CAThis salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. The Senior FAS, Protein XI will provide advanced technical support, engage in hands-on method development during an initial rotation at MSD headquarters, and mentor junior members of the Field Applications team.
NewSr. Staff Scientist - Protein Sciences R&D Twist Bioscience CorporationSr. Staff Scientist - Protein Sciences R&DUSA - South San Francisco, CA$180,000–$232,000 / yearKey Responsibilities: Develop small- and medium-scale antibody production workflows, including various formats (single-chain, IgG, multi-specific), culture systems, and purification methods. What You'll Bring to the Team: Deep hands-on experience designing, expressing, and optimizing monoclonal antibodies, with demonstrated understanding of Fc structure-function relationships (effector function, stability, manufacturability).
NewSr Manager Protein Sciences Twist Bioscience CorporationSr Manager Protein SciencesUSA - South San Francisco, CA$189,000–$224,000 / yearKey Responsibilities: Develop small- and medium-scale antibody production workflows, including various formats (single-chain, IgG, multi-specific), culture systems, and purification methods. What You'll Bring to the Team: Deep hands-on experience designing, expressing, and optimizing monoclonal antibodies, with demonstrated understanding of Fc structure-function relationships (effector function, stability, manufacturability).
Senior Scientist, Protein Assay Development - Spatial Biology 10X Genomics IncSenior Scientist, Protein Assay Development - Spatial BiologyPleasanton, CAWe also want to encourage you to apply to 10x Genomics positions directly on our careers site, https://careers.kula.ai/10xgenomics?pid=171812447059&domain=10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. About the role: We are looking for an exceptional, multidisciplinary scientist to drive new research and product development efforts in our Spatial Biology department, developing technologies that map protein - and other biomolecules - directly within intact tissue.