Model-Based Systems Engineer (MBSE) GCR Professional ServicesModel-Based Systems Engineer (MBSE)Woburn, Massachusetts$75–$90 / hourContractorRole can be Hybrid, TBD The Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, and in Digital Engineering/Model-Based Systems Engineering (MBSE) achieving architectural integrity and traceability through requirements analysis, system and software development and production system deployment. The ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, and Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization.
NewLooker Data Modeling Engineer RESOURCESOFT, INC.Looker Data Modeling EngineerLexington, MAWe engage them in technology centric client projects that provide opportunities for them to evolve, innovate and deliver world class products and services. We partner with leading organizations to provide technology solutions within the financial, insurance, education, government, publishing, healthcare and pharmaceutical domains.
NewAssociate Director - Data Modeling 3316 Takeda Development Center AmericasAssociate Director - Data ModelingCambridge, Massachusettsdevelop knowledge graph products with functionality related to user-interfaces, views, search, LLM-augmented RAG (Retrieval Augmented Generative) conversational interfaces and other gen-AI components etc. to enable the dissemination of the knowledge & insights across R&D. As an Associate Director - Data Modeling, you will provide Data Modelling subject-matter-expertise to ensure high-quality analysis-ready data assets are created and utilized in a systematic manner for insight generation within R&D.
NewSenior Staff Engineer, Modeling and Data Applications 3316 Takeda Development Center AmericasSenior Staff Engineer, Modeling and Data ApplicationsLexington, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. D. degree or a M.S. degree in biochemical engineering/biotechnology, data sciences, predictive modeling or closely related fields with 3+ years (PhD.) or 10+ years (M.S.) of experience in modeling and bioprocess development.
Senior Director, QSP/ PBPK Modeling Kiniksa Pharmaceuticals CorpSenior Director, QSP/ PBPK ModelingLexington, MA$281,000–$299,000 / yearStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
NewSenior Staff Engineer, Modeling and Data Applications Takeda Pharmaceutical Co LtdSenior Staff Engineer, Modeling and Data ApplicationsLexington, MA$137,000–$215,270 / yearThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. D. degree or a M.S. degree in biochemical engineering/biotechnology, data sciences, predictive modeling or closely related fields with 3+ years (PhD.) or 10+ years (M.S.) of experience in modeling and bioprocess development.
Associate Director - Data Modeling Takeda Pharmaceutical Co LtdAssociate Director - Data ModelingCambridge, MA$154,400–$242,550 / yearAbout the role: As an Associate Director - Data Modeling, you will provide Data Modelling subject-matter-expertise to ensure high-quality analysis-ready data assets are created and utilized in a systematic manner for insight generation within R&D. develop knowledge graph products with functionality related to user-interfaces, views, search, LLM-augmented RAG (Retrieval Augmented Generative) conversational interfaces and other gen-AI components etc. to enable the dissemination of the knowledge & insights across R&D.
Associate Director or Director, PBPK & Biopharmaceutics Modeling Kymera TherapeuticsAssociate Director or Director, PBPK & Biopharmaceutics ModelingWatertown, MA$160,000–$275,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Experience modeling oral molecules with challenging developability profiles, including poorly soluble and/or permeable compounds and beyond-rule-of-five modalities such as targeted protein degraders (preferred).
Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation GSK plcDirector, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and SimulationWaltham, MA$188,100–$313,500 / yearBasic Qualifications: We are looking for professionals with these required skills to achieve our goals: A PhD in Quantitative Clinical Pharmacology and Pharmacometrics (e.g., pharmacology, engineering or statistics) or relevant Life Sciences discipline, and experience in using modelling/simulation to solve practical problems in industry or academia. Drug Design, Drug Development, Drug Discovery Process, Drug Discovery Research, Medication Safety, Molecular Modeling, Pharmaceutical Regulatory Compliance, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Pharmacovigilance, Study Design, Target Validation.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation MIT Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Senior Machine Learning Scientist I/II, Model-Driven Optimization Generate BiomedicinesSenior Machine Learning Scientist I/II, Model-Driven OptimizationSomerville, MassachusettsThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
Senior Research Scientist, Large Behavior Models Toyota Research InstituteSenior Research Scientist, Large Behavior ModelsCambridge, MA$180,000–$258,750 / yearBackground or familiarity with some of the following: motion control and actuation, whole-body control, reinforcement learning, robot teleoperation methods, common communication protocols, research robotic arms/systems, visual perception and depth sensors, machine learning, robotic simulation, force and tactile sensing systems, haptic interfaces. A strong track record of impact, either via first author research publications at top-tier machine learning or robotics conferences (RSS, NeurIPS, ICML, CoRL, ICRA, IROS, …), or via meaningful contributions to successful industry initiatives.
Distinguished Scientist, Transgenic Model And Technology SanofiDistinguished Scientist, Transgenic Model And TechnologyCambridge, MA$178,500–$257,833.33 / yearAs the Global Head of Transgenic Biology, you will ensure our organization remains at the forefront of technical developments in genome engineering, enabling breakthrough discoveries in immunology, immuno-inflammation, rare diseases, neuroscience, and oncology. Deep expertise in developing transgenic animal models, including engineering diverse genetic alleles using CRISPR/Cas9, Cas12, base editors, prime editors, and other advanced genome engineering systems.
Senior Distinguished Scientist for Transgenic Model and Technology SanofiSenior Distinguished Scientist for Transgenic Model and TechnologyCambridge, MA$178,500–$257,833.33 / yearAs the Global Head of Transgenic Biology, you will ensure our organization remains at the forefront of technical developments in genome engineering, enabling breakthrough discoveries in immunology, immuno-inflammation, rare diseases, neuroscience, and oncology. Deep expertise in developing transgenic animal models, including engineering diverse genetic alleles using CRISPR/Cas9, Cas12, base editors, prime editors, and other advanced genome engineering systems.
Model Based Systems Engineer Actalent IncModel Based Systems EngineerWoburn, MA$52–$80 / hourThe division considers the entire solution lifecycle-from conceptualization and architecture through development and deployment-while leveraging novel technologies to deliver sustainable, reliable, and cost-efficient products that operate in realistic, operationally relevant environments and timeframes. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing winner for both client and talent service.
Associate Director or Director, PBPK & Biopharmaceutics Modeling Kymera Therapeutics IncAssociate Director or Director, PBPK & Biopharmaceutics ModelingWatertown, MA$160,000–$275,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Experience modeling oral molecules with challenging developability profiles, including poorly soluble and/or permeable compounds and beyond-rule-of-five modalities such as targeted protein degraders (preferred).
Research Scientist, VLA Models - Atlas Boston Dynamics, inc.Research Scientist, VLA Models - AtlasWaltham, MAYour work will focus on building models that take multimodal input (vision, language, task context, robot state), and produce grounded actions that generalize across manipulation tasks, embodiments, and environments. You will design large-scale behavior cloning and imitation learning pipelines, build hierarchical skill systems, and integrate learned components into a complex, real-world robotic system.
Principal Model-Based Systems Engineer STRPrincipal Model-Based Systems EngineerWoburn, MassachusettsThe ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization. In addition to modeling in SysML, the Systems Engineer will be responsible for implementing and guiding teams in the customization and automation techniques offered by Cameo to enable multi-disciplinary programs to comply with DoD Digital Engineering goals.
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting) Novartis AGPrincipal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)Cambridge, MA$126,000–$234,000 / yearEngage in strategic initiatives within M&S, such as creating platform-level translational modeling strategies to impact across projects and developing modeling workflows (e.g., agentic AI).• Proactively seek opportunities to increase the understanding and adoption of translational modeling among internal partners and expand the impact and visibility of modeling through external collaborations. As part of a truly translational modeling team, you will also work closely with clinical pharmacology and pharmacometrics groups to support clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions from early dose optimization through life-cycle management.
Model Based Logistics/Product Support Engineer BAE Systems PlcModel Based Logistics/Product Support EngineerNashua, NHRemote$118,095–$200,762 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. You would be part of a highly visible trailblazing team of Product Support champions and other SMEs charged with collaborating with project teams and other leaders to contribute to the creation of MBPS training materials and company best practices that help develop and guide our MBPS implementation roadmap.