Principal Software Engineer ZipStaff Inc.Principal Software EngineerBlue Bell, PennsylvaniaRemote$58–$60You will architect Java / Spring Boot services, optimize high-throughput SQL workloads, own Kafka event-streaming pipelines, and mentor a team of 4–8 engineers. About the Opportunity: ZipStaff is seeking a Principal Software Engineer to lead design and delivery of scalable microservices for a leading healthcare analytics organization.
SAP S/4 EPPM SME (Principal) - Remote with Travel The Dignify Solutions, LLCSAP S/4 EPPM SME (Principal) - Remote with TravelNewtown Square, PARemoteDesigns how project and portfolio performance is reviewed with real-time data from financial controlling and human resource management. Principal SAP S/4HANA architect for Enterprise Portfolio and Project Management (EPPM).
Principal Architect - Data EDI StaffingPrincipal Architect - DataCollingswood, NJEnterprise-Wide Architectural Data Leadership Define and evolve the enterprise data architecture across key data domains, including data platforms, integration, governance, analytics, and data security, ensuring cohesive and scalable end-to-end data solutions. Enterprise Data Strategy Development: Demonstrates the ability to design and implement comprehensive data strategies that support diverse use cases, including analytics, real-time transactional processing, bulk data movement, and API-driven data access.
Principal, General Servicing Lakeview Loan ServicingPrincipal, General ServicingHorsham, PennsylvaniaRemote$128,000–$145,000 / yearFull timeReporting to the Director of Servicing Product, this role operates within the broader servicing product structure and brings shared-services domain expertise into requirements definition, workflow validation, testing support, and implementation discussions to ensure that platform functionality accurately reflects real-world servicing operations, regulatory expectations, and vendor dependencies. Instead, this position is designed for a deeply experienced servicing subject matter expert who understands, in detail, how shared servicing infrastructure enables consistent execution across borrower communications, vendor interactions, and cross-domain workflows, and can translate that expertise into scalable product capabilities.
Managing Principal HDR IncManaging PrincipalPhiladelphia, PAUnited States-Pennsylvania-Philadelphia'',''United States-Pennsylvania-Philadelphia'','''','''','''','''','''','''','''','''',''Architecture'',''Architecture'',''Full-time'',''Full-time'',''Regular'',''Regular'','''','''',''Gen Architecture'',''Gen Architecture'',''Apr 22, 2026'',''Apr 22, 2026'',''false'',''781593'',''781593'',''true'',''781593'',''false'',''Submission for the position: Managing Principal - (Job Number: 192608)'',''false'',''781593'',''false'',''true''. This individual will oversee and direct the activities of personnel within the office including implementing annual plans, marketing strategies, public relations, project planning, financial planning and management, staff planning and oversight and other related matters.
Principal Biostatistician Penfield Search PartnersPrincipal BiostatisticianPhiladelphia, PAOur client is a global organization focused on advancing novel therapies for patients with rare diseases, with a clinical pipeline spanning multiple stages of development and therapeutic areas including immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. Utilizing three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy, the company continually refines ways in which products can address unmet medical needs and help patients lead full lives.
Principal Engineer, Packaging Equipment Validation & Engineering Group, IncPrincipal Engineer, Packaging EquipmentFort Washington, PAValidation & Engineering Group, Inc. (V&EG) a Pinnaql company is a leading services supplier who provides solutions for the Pharmaceutical, Biotechnology, Chemical, Food, and Medical Devices industries in the following areas: Laboratory, Compliance, Computer, Engineering, Project Management, Validation, and other services. The individual will provide technical leadership for packaging equipment while collaborating with Manufacturing, Operations, Research & Development, Marketing, Market Research, Supply Chain, Process Excellence, and other affiliated functions to identify and address packaging equipment and/or validation needs.
NewPrincipal Manufacturing Engineer Karman Holdings IncPrincipal Manufacturing Engineerhorsham, PAOur bow-to-stern capabilities include acoustic and sonar protection systems, propulsion systems, advanced composite structures, missile subsystems, canisters and launchers, and autonomous underwater vehicle subsystems. This role is part of our Maritime Defense Systems business, which delivers integrated solutions with decades of proven performance across submarine, surface, and autonomous naval platforms supporting high-priority national defense programs.
Experienced Structural Engineer | Associate Principal Wiss Janney Elstner AssociatesExperienced Structural Engineer | Associate PrincipalPhiladelphia, Pennsylvania$110,700–$184,500 / yearTechnical leadership, including applying sound engineering judgement and a deep understanding of governing codes, design guidelines, and industry practices; collaborating with interdisciplinary project teams across WJE as the structural engineering subject-matter expert (SME); leveraging your expertise for a variety of structural engineering projects, including the investigation, design, analysis, repair, and renovation of new and existing structures, construction materials, loading conditions, and construction types; preparing technically excellent client deliverables; providing high-quality reviews and oversight of work by others; and performing and training others in hands-on fieldwork. Minimum twenty years of relevant structural engineering industry experience, including technical and project management (e.g., failure/damage investigation; non-destructive evaluation and instrumentation; structural analysis and design for repair, retrofit, and rehabilitation of existing structures; evaluation of parking garage structures; and/or specialty consulting of new systems and materials from design through construction).
Associate Principal Scientist, Clinical Research Merck & Co IncAssociate Principal Scientist, Clinical ResearchWest Point, PA$142,400–$224,100 / yearTranslational Medicine (TMed) drives early clinical development of novel therapeutics by partnering with Discovery Sciences and Late-Stage Clinical Research to translate scientific discoveries into human proof-of-concept and advance the most promising candidates through the pipeline to patients. Leads and directs teams through key study planning, development, and execution activities, including program overviews, issue escalation and mitigation, senior management presentations, cross-functional governance meetings, and advisory meeting preparation.
Principal Scientist (Director) - Outcomes Research Merck & Co IncPrincipal Scientist (Director) - Outcomes ResearchNorth Wales, PA$190,800–$300,300 / yearPrimary Responsibilities: This position has primary responsibility for planning/managing a comprehensive program of real-world evidence and non-interventional research activities for in-line and pipeline products for lung cancers to meet the value evidence needs of clinicians, payers, policymakers, health technology assessment (HTA)/reimbursement agencies, and health systems globally. The following skills and knowledge are needed to be successful in this role: Decision making: Identifying and understanding problems and opportunities by gathering, analyzing and interpreting quantitative and qualitative information; choosing the best course of action by establishing clear decision criteria, generating and evaluating alternatives, and making timely decisions; taking action that is consistent with available facts and constraints and optimizes probable consequences.
(Sr.) (Lead) (Principal) Energy Analyst/Engineer (II) PJM Interconnection LLC(Sr.) (Lead) (Principal) Energy Analyst/Engineer (II)PALead) Analyst/Engineer will support the Capacity Market Operations Department to successfully manage the $12 billion per year PJM Capacity Market that is used to ensure the reliability of the PJM system. The candidate will also help with the financial analysis of default minimum offer prices, default maximum offer prices, reference resource price used to determine the demand curve and power plant estimated net revenues.
Associate Principal Scientist/Engineer, Medical Device and Combination Products, Analytical Merck & Co IncAssociate Principal Scientist/Engineer, Medical Device and Combination Products, AnalyticalWest Point, PA$142,400–$224,100 / yearRequired Skills: Analytical Chemistry, Computed Tomography (CT), Cross-Cultural Awareness, Design Validations, Design Verification, Design Verification Testing, Device Characterization, Interdisciplinary Collaboration, Materials Characterization, Mechanical Testing, Medical Devices Engineering, Microscopies, Professional Networking, Rheometry, Tensile Strength Testing, Tomography, X Ray Imaging. The role will naturally include substantial technical creative challenge for Device Characterization and more formal Design Verification, which includes development & validation of mechanical test methods as well as coordination & technical oversight for internal CPDA staff or external lab testing (where required) to meet project timelines and deliverables.
Principal Scientist, Stat. Programming - A&R Standards, Innovation (Hybrid) Merck & Co IncPrincipal Scientist, Stat. Programming - A&R Standards, Innovation (Hybrid)North Wales, PA$173,200–$272,600 / yearIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Superior knowledge and significant experience in setting strategy and developing analysis and reporting statistical programming deliverables (datasets, statistical analyses, report tables, and graphics) according to quality, compliance and timeliness requirements.
Associate Principal Scientist, Toxicology/Study Director Merck & Co IncAssociate Principal Scientist, Toxicology/Study DirectorWest Point, PA$142,400–$224,100 / yearRequired Skills: Animal Studies, Effective Written Communication, Evaluate Information, Good Laboratory Practices (GLPs), Oral Communications, Proactive Thinking, Study Directing, Study Monitoring, Teamwork, Toxicology. Our toxicologists provide scientific leadership in the design and overall conduct of in vivo studies and integrate the findings from all contributing scientists into reports that characterize the safety profile of drug candidates.
Sr. Principal Scientist, Nonclinical Drug Safety Merck & Co IncSr. Principal Scientist, Nonclinical Drug SafetyWest Point, PA$190,800–$300,300 / yearStrategically influence nonclinical drug safety considerations for Immunology programs by providing drug development mentorship and partnering with Compound Leaders on time-critical matters, including nonclinical program design and toxicology study design, weight-of-evidence risk assessments, science-based waiver strategies, and integrated safety development plans that support clinical trials, global registration, and timely resolution of nonclinical development issues. Provide scientific and strategic oversight for Immunology candidates through close collaboration with Program Coordinators, Discovery Preclinical Leaders, Compound Leaders, and scientists across NDS and/or Preclinical Development, while ensuring strong partnership with key Research and Development Division functions, including Discovery, chemistry, regulatory affairs, translational medicine, clinical development, and CMC.
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety Merck & Co IncPrincipal Scientist (Scientific Director Level)- Nonclinical Drug SafetyWest Point, PA$176,200–$277,300 / yearThey are responsible for 1) providing risk assessments for targets, 2) de-risking strategies for discovery programs and 3) collaborating with NDS staff at other sites to execute on the appropriate studies to support selection of therapeutic targets, and the identification and development of new drug candidates. The Discovery Program Leader is responsible for defining and overseeing the NDS strategy for programs in all modalities (including small molecules, peptides, biologics and ADC programs) from Target Identification through to the approval of First-In-Human enabling GLP toxicity studies.
Principal Scientist, Drug Product Steriles Primary Packaging GSK plcPrincipal Scientist, Drug Product Steriles Primary PackagingCollegeville, PADrug Delivery, External Manufacturing, Medical Device Evaluation, Molecular Modeling, Pharmaceutical Formulations, Pharmacokinetics, Product Design, Product Management, Product Planning, Product Strategies, Quality by Design, Regulatory Filings, Stability Testing, Technology Transfer. Formulation Product Development: Understanding of actives, raw materials and their function and how they are brought together to form a stable, functioning product from prototype evaluation to commercial launch Job Family - Product Development: Manages or contributes to development of the company's products.
Associate Principal Scientist, Statistical Programming, Late-Stage Oncology (Hybrid) Merck & Co IncAssociate Principal Scientist, Statistical Programming, Late-Stage Oncology (Hybrid)North Wales, PA$142,400–$224,100 / yearIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our Company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Required Skills: Base SAS, Clinical Development, Data Management, Data Modeling, FDA Submissions, Influencing Skills, Oncology, Presentation Delivery, Process Improvements, Project Management, Project Planning, Resource Planning, Stakeholder Management, Statistical Programming, Strategic Planning, Strategic Thinking.
Senior Principal Scientist, Veterinary Pathology Board Certified Merck & Co IncSenior Principal Scientist, Veterinary Pathology Board CertifiedWest Point, PA$231,900–$365,000 / yearRequired Skills: Analytical Assays, Analytical Assays, Assay Development, Biomedical Sciences, Biotechnology, Clinical Assays, Clinical Data Interpretation, Clinical Judgment, Clinical Safety, Drug Development, Drug Discovery Research, Drug Research, Histopathology, Immunochemistry, Immunology Research, Innovation, In Vitro Research, In Vivo Models, Laboratory Processes, Medical Biology, Molecular Diagnostic Techniques, Pathogenesis, Pharmaceutical Research, Post Mortem Analysis, Safety Pharmacology {+ 3 more}. Our Company's Research Laboratories nonclinical drug safety department at West Point, Pennsylvania site is seeking an experienced anatomic pathologist to join a highly collaborative team of scientists (12 anatomic pathologists, 3 clinical pathologists, and approximately 40 exceptional laboratory scientists), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories.