Principal Radar Systems Engineer GCR Professional ServicesPrincipal Radar Systems EngineerWoburn, MassachusettsContractorClient is focused on delivering National Defense capabilities by driving mission-focused strategies to develop advanced technology systems enabling enduring products and solutions focused on achieving the customer vision. Applicants are expected to be self-motivated, detail oriented and have a demonstrated ability to effectively communicate with all levels of management and individual contributors on the program team through strong written and verbal communication skills.
NewProgram Manager, Principal - Secret DCS CorpProgram Manager, Principal - SecretBedford, Massachusetts$123,639–$199,000 / yearIn this Advisory and Assistance Services (A&AS) role, you will provide expert-level support to Department of Defense (DoD) programs by assisting government leadership with decision-making, planning, and execution throughout the acquisition lifecycle. DCS has an exciting opportunity for a Program Manager SME (Principal) supporting the Air Force Life Cycle Management Center/PEO Electronic Systems Directorate (AFLCMC/HB) within the HBU Force Protection Division at Hanscom AFB.
Principal Software Engineer - AI New BalancePrincipal Software Engineer - AIBrighton, MA$120,000–$150,000 / yearA core focus of this role is designing and building enterprise-grade AI assistants and automations using RAG and agentic AI techniques -software agents that can plan, coordinate tools, interact with systems, and execute multi-step workflows with appropriate guardrails. This team is responsible for researching and delivering AI based solutions across the company to improve internal workflows, decision-making, and operational efficiency across a wide range of business functions, including operations, supply chain, finance, product, and corporate services.
Principal Consultant - Aviation Noise HARRIS MILLER MILLER & HANSON INC.Principal Consultant - Aviation NoiseBURLINGTON, MARemoteWe are seeking a Principal Consultant – Aviation Noise to join our team in a remote or hybrid position in the U.S. In this senior role, you will serve as a recognized technical expert in aviation noise, leading large and complex projects, supervisingand mentoringstaff, shaping practice strategy, and expanding HMMH’s presence in the aviation noise field. Our Aviation Environmental & Sustainability Group supports over 200 airports worldwide with noise and air quality studies, sustainability plans, mitigation strategies, environmental documentation, and regulatory compliance.
Resiliency Associate/Principal Planner Central Mass Regional Planning CommissionResiliency Associate/Principal PlannerWorcester, MA$52,538–$80,000 / yearTypical duties may include: · Contribute to or lead the development of a wide variety of planning initiatives and regional and municipal support activities, including climate resiliency initiatives, energy efficiency initiatives, hazard mitigation planning, open space and recreation planning, trail mapping, climate pollution reduction planning, and related efforts. The position will support open space and recreation plans, hazard mitigation plans, climate pollution reduction, energy reduction, resiliency planning, trail mapping, and related municipal and regional planning initiatives, with opportunities to contribute to comprehensive master plans, economic development plans, housing plans, and similar efforts.
Principal Product Manager - EAMC ImprivataPrincipal Product Manager - EAMCWaltham, MA$180,600–$191,100 / yearAt Imprivata, we deliver unified access and security management programs that eliminate friction, empowering healthcare and mission-critical organizations to work smarter, faster, and more securely. The Principal Product Manager is responsible for Imprivata's Enterprise Access Management Cloud offering and the overall success of that business area, including adoption and growth.
Senior/Principal Scientist, Analytical Cell Line Engineering and Bioassay Development 3316 Takeda Development Center AmericasSenior/Principal Scientist, Analytical Cell Line Engineering and Bioassay DevelopmentLexington, Massachusetts$154,400–$242,550 / yearHow you will contribute: Lead the design, generation, characterization, and lifecycle management of stable mammalian analytical cell lines expressing targets of interest, receptor systems, or reporter constructs to support potency and functional bioassays. Operating at the interface between Discovery, Global Biologics, Analytical Development, and late-stage potency teams, this role translates product mechanism of action into scientifically sound, phase-appropriate cell line and assay strategies.
Process Development Principal Scientist AmgenProcess Development Principal ScientistMassachusettsIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role as an Attribute Sciences team lead and group lead you will work to provide strategic analytical leadership to teams developing commercial manufacturing processes for synthetic and hybrid molecules and collaborate closely with Drug Substance, Drug Product and Product Quality colleague.
Principal Thermal Mechanical Engineer FlexPrincipal Thermal Mechanical EngineerLittleton, MA$153,500–$211,000 / yearWhat a typical day looks like: Lead the initial design, analysis, and optimization of complex fluid systems from concept initial CAD to final detailed CAD and drawing for liquid cooling, including cold plates, pumps, fluids, tubing, and heat exchangers, for the latest computer processing chipsets. The Principal Mechanical Engineer will provide technical leadership, mentorship, and hands-on expertise in mechanical design, fluid dynamics, and heat transfer but also work closely with customers in communicating the art of the possible with JetCool technology and building a strong customer relationship on a technical level.
Principal Program Scheduler Torch TechnologiesPrincipal Program SchedulerHanscom AFB, Massachusetts$145,000–$160,000 / yearBy enabling aircrews to electronically receive and process tasking orders, intelligence inputs, target coordinates, and mission‑critical flight and weapons data, MPS enhances combat effectiveness, increases sortie generation rates, and improves aircrew readiness and survivability across the Combat Air Forces (CAF) and Mobility Air Forces (MAF). Several factors can influence the salary for a position including but not limited to, Federal Government contract labor categories and contract wage rates, geographic location, business considerations, scope and responsibilities of the position, local or other applicable market conditions, and internal equity.
Principal Application Scientist Revvity, Inc.Principal Application ScientistHopkinton, MA$120,000–$155,000 / yearWorking with key commercial entities, you will craft automation methods & workflows that will be disseminated globally, allowing Revvity specialist to support internal sales specialists and customers with novel and well annotated automation methods, allowing Revvity to continue to lead the field. The individual is expected to support the global Revvity automation business by expanding instrument capabilities, working as necessary with technical support to troubleshoot complex customer issues, and providing training and marketing material for new application capabilities that will be used to support the sales of automation instruments globally.
Principal RA Associate Devices Fresenius Medical CarePrincipal RA Associate DevicesWaltham, MassachusettsResponsible for preparing FDA submissions necessary for new product approvals/clearances which include Premarket norifictoins-510(k)s, Premarket Approval Applications (PMAs) and supplements, Investigational Device Exemptions (IDEs) submissions. Serves as the primary regulatory resource for change to and prioritization of projects, resource assignment and efficient management of the development and change processes.
Senior/Principal Scientist Cell Based Potency Assay 3316 Takeda Development Center AmericasSenior/Principal Scientist Cell Based Potency AssayLexington, MassachusettsD. in cell biology, molecular biology, immunology, biochemistry, bioengineering, pharmaceutical sciences, statistics, biostatistics, or a related discipline with 3+ years of relevant experience for Senior Scientist or 7+ years for Principal Scientist; MS with 9+ years for Senior Scientist or 13+ years for Principal Scientist; or BS with 11+ years for Senior Scientist or 15+ years for Principal Scientist. Plan and coordinate work with departmental, cross-functional, and external stakeholders, including Process Development, Quality Control, contract testing laboratories, Analytical Sciences, Quality Assurance, Regulatory, and other Analytical Development teams.
Principal Carelon Research Biostatistician Elevance HealthPrincipal Carelon Research BiostatisticianNewton, MassachusettsThis researcher partners with investigators, research sponsors, academic institutions, and cross-functional project teams to design studies, develop statistical methodologies, oversee analytical execution, and communicate scientific findings that advance externally funded clinical research programs. The Principal Carelon Research Biostatistician is responsible for serving as the statistical lead for complex clinical research studies and represents an analytical thought leader across Carelon Research's clinical research portfolio.
Principal Engineer, CMC Development Pilot Operations ModernaTXPrincipal Engineer, CMC Development Pilot OperationsNorwood, MassachusettsThe Principal Engineer will partner closely with CMC Dev Quality, analytical testing laboratories, Process Development, Engineering, Safety, Digital, and the GMP manufacturing facility to ensure seamless material delivery, technical readiness, operational excellence, and robust transfer of product and process knowledge across the manufacturing network. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Principal Specialist, Quality Assurance Cardinal HealthPrincipal Specialist, Quality AssuranceMansfield, MassachusettsCross-functional Collaboration: Leads complex cross-functional projects to identify root causes of significant quality issues, educates stakeholders on quality requirements, and develops sustainable solutions to minimize future risks. The Principal Specialist, Quality Assurance, is a highly experienced individual contributor who applies advanced knowledge of quality assurance concepts and technical capabilities to drive uncompromised laboratory integrity and minimize risks.
Principal C# Engineer / Technical Lead Integrated Computer SolutionsPrincipal C# Engineer / Technical LeadWaltham, MassachusettsICS blends the art of visual design and agile engineering to help our clients develop their products into devices that delight in a wide range of technologies. As a Principal Engineer / Technical Lead, you will be responsible for the design, development, and testing of software products in the Microsoft stack in the MedTech and industrial space.
Principal Scientist SanofiPrincipal ScientistWaltham, MA$122.25–$176.58 / hourThe Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviral vectors and cell therapy products. Main responsibilities: Lead scale-up activities from bench scale to pilot scale (200L-2000L), applying engineering principles (mixing, mass transfer, shear stress, dissolved oxygen control) to ensure process comparability at large scale.
Principal Scientist, Systems And Disease Biology SanofiPrincipal Scientist, Systems And Disease BiologyCambridge, MA$122.25–$176.58 / hourD. in systems biology, computational biology, biostatistics, or related quantitative field with proven experience in a relevant disease area (Immunology, Neurology or Oncology) OR PhD in biological sciences, biomedical sciences, immunology, neuroscience, oncology or in a related disease area and proven advanced track record of data analytics, ML/AI, or computational biology. Leading projects involving internal experiment design and data analytics as well as outsourcing of established workflows and/or complex follow-up mechanistic assays (organoid, CRISPR, proteomics).
Positively Partners Principal Consultant, Organizational Effectiveness Positively PartnersPositively Partners Principal Consultant, Organizational EffectivenessSouth Attleboro, Fully Remote (US)RemoteMany consulting engagements occur alongside broader partnerships delivered through PositivelyHR, our subscription-based outsourced HR service providing embedded HR leadership, systems, compliance, payroll administration, and day-to-day people support. As a Principal Consultant, Organizational Effectiveness, you will serve as a trusted advisor to nonprofit executives, partnering with leaders to solve complex organizational challenges and build stronger, healthier workplaces.