123 Results for

Principal Jobs in Shrewsbury, MA

Jobs

Billerica, MA13 days ago

Drive product development from concept through manufacturing, including: System architecture and conceptualization. Ability to innovate and apply new technologies or existing methods to solve complex design challenges.

New!

Bedford, MA4 days ago

$123,639–$145,000 Per Year

Command, Control, Communications, and Battle Management (C3BM) has been tasked with delivering an integrated Department of the Air Force (DAF) Battle Network providing resilient decision advantage and enabling the USAF, USSF, Joint, and Coalition Force to win against the pacing challenge. C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space.

Andover, MA13 days ago

Translate engineering design requirements into formal manufacturing process documentation including raw material definition, fixturing/tooling development, CNC programming, inspection planning, finishing requirements, and assembly instructions. Qualifications You Must Have: * Typically requires a Bachelor's Degree in Manufacturing Engineering, Mechanical Engineering, Industrial Engineering, Electrical Engineering, or Aerospace Engineering.

Lancaster, MA30+ days ago

Must assist in enforcing the school code of conduct, testing and assessment programs, preparation of student and class schedules, assist all custodial, cafeteria, and other support services, assist in all curriculum matters. Assist parents through prompt communication and support for the purpose of impacting and improving students' academic performance.

Andover, MA30+ days ago

$112,700–$187,800 Per Year

Team leader responsible for the safety and oversight of Technical Programs laboratory-based and at-scale work, including small-scale cleaning validation program requirements, mixing qualification, and solution chemical stability and expiry. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Natick, Massachusetts30+ days ago

$200,000–$300,000 Per Year

Andover, MA15 days ago

Translate engineering design requirements into formal manufacturing process documentation including raw material definition, fixturing/tooling development, CNC programming, inspection planning, finishing requirements, and assembly instructions. Typically requires a Bachelors Degree in Manufacturing Engineering, Mechanical Engineering, Industrial Engineering, Electrical Engineering, or Aerospace Engineering.

New!

Waltham, MA5 days ago

$155,000–$190,000 Per Year

Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. Lead system-level analysis and risk mitigation strategies related to battery thermal behavior and heat dissipation, including charging scenarios, environmental extremes, and long-term reliability to ensure patient safety and regulatory compliance.

New!

Waltham, MA5 days ago

$120,000–$160,000 Per Year

Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. With headquarters in Norwood and Waltham, Massachusetts, and a global team of nearly 2,000 employees, we’re building a collaborative, empowered culture grounded in shared values: Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity.

BURLINGTON, MA30+ days ago

Remote

We are seeking a Principal Consultant – Aviation Noise to join our team in a remote or hybrid position in the U.S. In this senior role, you will serve as a recognized technical expert in aviation noise, leading large and complex projects, supervisingand mentoringstaff, shaping practice strategy, and expanding HMMH’s presence in the aviation noise field. Our Aviation Environmental & Sustainability Group supports over 200 airports worldwide with noise and air quality studies, sustainability plans, mitigation strategies, environmental documentation, and regulatory compliance.

Waltham, MA15 days ago

We are looking for an experienced researcher to join our team as Principal Research Associate/Associate Scientist in the Molecular Assembly team, supporting our novel target identification and validation workflow in house. Excellent written and verbal communication skills, with the ability to document experiments in an organized and timely fashion and to present scientific data to coworkers.

Lancaster, MA30+ days ago

The job of Principal - Elementary was estabished for the purpose/s of providing support to the instructional process with specific responsibility for directing overall site operations, services and staff at an elementary school; providing information and serving as a resource to others; enforcing established policies and regulatory requirements; coordinating school activities and addressing issues, situations and/or problems that arise on campus or with enrolled students. Minimum requirements: Master's degree, or higher in job related area, two years of administrative experience as well as five (5) years as a teacher preferred.

TEWKSBURY, MA30+ days ago

Provide technical direction across various stages of missile operations, including the disposition of field return assets, complex assembly and disassembly issues, and ensuring mission readiness for flight tests. _As part of our commitment to maintaining a secure hiring process, candidates may be asked to attend select steps of the interview process in-person at one of our office locations, regardless of whether the role is designated as on-site, hybrid or remote._.

Hanscom AFB, Massachusetts30+ days ago

C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space. Command, Control, Communications, and Battle Management (C3BM) has been tasked with delivering an integrated Department of the Air Force (DAF) Battle Network providing resilient decision advantage and enabling the USAF, USSF, Joint, and Coalition Force to win against the pacing challenge.

Hanscom AFB, Massachusetts22 days ago

The Air Force Program Execution Office for PEO Electronic Systems (ES) has the collective Air Force Materiel Command (AFMC) mission responsibility to manage and execute the modernization, development, testing, production, fielding, and sustainment of the PEO Digital portfolio, which includes over 130 programs for the United States Air Force (USAF) and foreign allies. Please Note: Final compensation for this position will be determined by various factors such as the Federal Government contract labor categories and contract wage rates, relevant work experience, specific skills and competencies, geographic location, education, and certifications.

Hanscom AFB, Massachusetts30+ days ago

Burlington, MA30+ days ago

Powered by trillions of lines of code scans and a proprietary AI-generated remediation engine, the Veracode platform is trusted by organizations worldwide to build and maintain secure software from code creation to cloud deployment. This role is ideal for an experienced professional who thrives in designing and maintaining scalable, secure, and cost-efficient CI/CD pipelines, Kubernetes clusters, and cloud-based systems.

Burlington, MA30+ days ago

Powered by trillions of lines of code scans and a proprietary AI-generated remediation engine, the Veracode platform is trusted by organizations worldwide to build and maintain secure software from code creation to cloud deployment. Strong understanding of various machine learning algorithms, including supervised and unsupervised learning, reinforcement learning, and neural networks.

Waltham, MA30+ days ago

Full-time

Working knowledge of advanced consulting methodologies, tools, and techniques – with focus on: leveraging AI, LLMs, and life sciences real-world data, for purposes such as patient finding, HCP segmentation, and other applications of advanced analytics, optimization of omnichannel plans, marketing mix, performance analytics and reporting related activities. 10+ years as a top performer within a top-tier biopharmaceutical / pharmaceutical strategy consulting firm serving industry leading clients and/or relevant experience with advanced analytics, omnichannel measurement, marketing analytics, and/or technology-enabled solutions within pharma and biotech.

Bedford / Hanscom AFB, Massachusetts21 days ago

$140,000–$150,000 Per Year

The Air Force Program Execution Office for PEO Electronic Systems (ES) has the collective Air Force Materiel Command (AFMC) mission responsibility to manage and execute the modernization, development, testing, production, fielding, and sustainment of the PEO Digital portfolio, which includes over 130 programs for the United States Air Force (USAF) and foreign allies. Astrion has an exciting opportunity for a PRINCIPAL LOGISTICS MANAGERproviding support to the Air Force Life Cycle Management Center (AFLCMC), PEO Electronic Systems (ES) located at HANSCOM AFB, MA.

Bedford / Hanscom AFB, Massachusetts30+ days ago

Astrion has an exciting opportunity for a Principal Data Links and Communications Engineerfor the EPASS Cyber and Networks Directorate (EPASS HN II) contract, supporting the Aerial Networks Division (AFLCMC/HNA) located at Hanscom AFB, MA. Support defining and documenting a set of Combat Net Radio (CNR) networking parameter configurations to provide the best balance between flexible implementation of capability and implementation impact on both existing and emerging weapon systems.

Waltham, MA13 days ago

$135,000–$145,000 Per Year

The position requires ownership of the accounting processes for multiple international entities, strong technical accounting expertise, attention to detail, problem-solving skills, and the ability to strategically collaborate cross-functionally. The day-to-day functions include journal entries, month-end close reconciliations, accounts payable review, cash management and local tax filings.

Westborough, MA30+ days ago

The major responsibilities of the position include guiding and overseeing product innovation activities (organic and inorganic), translating business strategies into product concepts, defining strategies for product specifications and design inputs, conceptual product design, and development/validation of preliminary business cases. Olympus Corporation of the Americas, a wholly owned subsidiary of Olympus Corporation, is headquartered in Center Valley, Pennsylvania, USA, and employs more than 5,200 employees throughout locations in North and South America.

Andover, MA30+ days ago

$160,000–$200,000

Kforce has a client that is seeking a Principal Hardware Design Engineer in Andover, MA to play a key role in the development of complex digital hardware systems from initial concept through production. Employee pay is based on factors like relevant education, qualifications, certifications, experience, skills, seniority, location, performance, union contract and business needs.

Burlington, MA30+ days ago

The Principal Electrical Engineer is a senior technical leader responsible for developing Butterfly's industry leading ultrasound products from concept to commercial launch and production scale-up. As part of our team, your core responsibilities will be: Lead electrical architecture and design for medical devices across the full product lifecycle, from early feasibility and risk analysis through design transfer, manufacturing, and post-market support.

Burlington, MA30+ days ago

With our proprietary Ultrasound-on-Chip technology, we're democratizing healthcare by shifting ultrasound from the expensive, stationary systems of the past to the connected, mobile, and software-enabled platforms of today. Immediately reporting any suspected or actual security incidents, including phishing attempts, malware infections, or unauthorized access, following the established incident response procedure.

Waltham, MA14 days ago

$137,000–$220,000

In accordance with state and local pay transparency laws—including those in California, Colorado, Massachusetts, New York, New Jersey, and others—we disclose salary ranges in all job postings and provide additional information upon request. In this role, you will partner closely with Platform, Security, Compliance, and Engineering teams to enable reliable, audit-ready cloud environments while balancing velocity, security, and operational excellence.

Waltham, MA27 days ago

Full-time

This individual, with some supervision, will independently drive synthesis, purification, formulation, and analytical characterization of modified oligonucleotides to support discovery and early development programs. In our fast-paced startup environment, this role requires strong technical skills, hands-on execution, problem-solving creativity, and a willingness to take ownership of processes and infrastructure as we scale.

Cumberland, RI30+ days ago

$120

This hybrid role bridges traditional Microsoft Information Protection and compliance tools with modern AI-centric data security practices, including encryption for LLM pipelines, secure vector stores, and legacy data remediation. - Looking for experience with Snowflake, Microsoft Defender, DLP tools, Azure Purview and with a data engineering background that is operating in an oversight role or assisting a larger organization using those tools.

Woburn, MA23 days ago

$140,000–$230,000 Per Year

One or more of the following credentials: certified public accountant (CPA), certified valuation analyst (CVA), accredited in business valuation (ABV), chartered financial analyst (CFA), certified business appraiser (CBA), accredited senior appraiser (ASA), certified divorce financial analyst (CDFA) CPA, CVA, ABV, CBA, or ASA certification is required 10+ years' of recent experience in a related field, with a proven ability to lead and develop client relationships. Proactively identifies and communicates issues to clients, provides value added advice; is viewed as a qualitative and quantitative resource for partners and staff to resolve issues within practice segments and/or industry specialization(s).

Cambridge Crossing, MA30+ days ago

$156,180–$189,252 Per Year

Hands-on experience using various cell line and PDX mouse models, humanized mouse models, admixture xenografts, orthotopic models to execute in vivo workflows enabling candidate selection for early clinical development is highly desired. Working closely with project teams and key stakeholders, lead the development of in vivo strategies from target concept to Proof of Concept in patients, applying scientific and technical skills and functional knowledge to complex projects.

Devens, MA30+ days ago

$124,590–$151,000 Per Year

Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Build effective relationships/partnerships and work cross-functionally with internal and external stakeholders to implement novel integrated automated systems to streamline execution and analysis of cell therapy assays.

Cambridge Crossing, MA30+ days ago

$166,770–$202,086 Per Year

Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN ), single cell (CITE-seq, scATAC-seq, perturb-seq) and spatial profiling (Visium, GeoMx, CosMX ). We seek a creative and passionate computational scientist to join the Neuroscience, Immunology, and Cardiovascular (NIC) discovery team within Informatics and Predictive Sciences, a globally distributed group driving innovative computational research for discovery and early development.

Burlington, MA30+ days ago

Experience with Git source control (Azure DevOps, GitHub, GitLab, etc.), mono-repos, short lived feature branches, branch management, and CI/CD pipelines (Jenkins, Azure DevOps, GitHub Actions, GitLab). The successful candidate will be responsible for development of automation solutions, collaborating with and enabling other teams to automate the lifecycle of their respective internal IT products and services, and evangelizing good software engineering practices across the IT organization.

Woburn, Massachusetts10 days ago

$65–$70 Per Hour

Nice-to-Haves:Experience with UI frameworks (Angular, React, Ember, Bootstrap). Apply now: Principal Software Engineer, location is Hybrid (Woburn, Westborough, MA or Cary, NC).

Bedford / Hanscom AFB, Massachusetts24 days ago

$150,000–$180,000 Per Year

Prepare technical documentation to define and recommend system/subsystem characteristics; produce management reports and technical presentations for planning, implementation, and corrective actions. Conduct program portfolio reviews to evaluate/recommend alternative plans, improve engineering processes, sustain program baselines, and validate system-level performance in accordance with specifications.

Bedford / Hanscom AFB, Massachusetts30+ days ago

$140,000–$150,000 Per Year

Bedford / Hanscom AFB, Massachusetts14 days ago

The BMC Remedy Architect Principal position is located at Hanscom AFB, MA and focuses on providing acquisition program management support for Cyberspace Security and Control System (CSCS) programs. Defines, writes, and delivers specifications, user guides, and architecture and methodology as appropriate to meet project deadlines.

Tewksbury, MA30+ days ago

ACTIVE US Secret Clearance REQUIREDDesired Skill Sets:* Experience using test equipment, software installations, and integrating or regression testing systems with certifications in CompTIA Network+ and or CompTIA Security+.* Experience with MATLAB, Linux Operating Systems (Linux Red Hat), Unix, Perl, C/C++, and Shell scripting for performing integration, verification and test analysis, integrating and configuring electronics/network routers, and installing/debugging software.* Experience with agile and DevSecOps processes, implement (or maintain) agile methodologies, participating in daily team standup meetings, sprint reviews, program Increment (PI) Planning meetings, retrospectives, and agile tooling such as JIRA and Confluence, and support execution of the team"s backlog including performance analysis and issue investigation.*

Medway, MA30+ days ago

Work with the Global Planning Functions to develop short and long term global strategies to ensure that we balance service and inventory tradeoffs while maintaining healthy partnerships, effective supply flow and a globally leveraged buying process . Develops, implements, and executes a globally aligned inventory management strategy that drives highly visible customer service levels, logistical flows, and effective turns which allow for flexibility and marketplace health.

Marlborough, MA30+ days ago

Analyze and review project data, correct errors, and report results for multiple projects to support research and development primarily focused on oligonucleotides. Subject matter expert analytical chemistry knowledge including theory and application of three or more chromatographic and spectroscopic techniques for identification, purity, and assay of various analytes .

Marlborough, MA30+ days ago

Review analytical data and reported results for completeness and accurately transfer technical information into written format using tables, graphs, text, or other means to present data and results clearly and completely. The Principal Technical Writer is responsible for originating and reviewing analytical documentation in accordance with SOPs in support of analytical deliverables across multiple projects.

BEDFORD, MA30+ days ago

Full-time

Founded in 2003 by a team of Taiwanese-American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung. The successful candidate will play a critical role in shaping therapeutic concepts and leading programs from early-stage discovery through IND-enabling studies, with significant influence over scientific strategy and key program-level decisions.

BEDFORD, MA30+ days ago

Full-time

Required QualificationsPhD in Immunology, Protein Engineering, Biochemistry, Molecular Biology, or a related field, with 7+ years of relevant industry experience in biologics or protein therapeutics discovery (4+ years for Senior Scientist level). The successful candidate will combine deep expertise in protein engineering, antibody and multispecific formats, and immuno-oncology biology with strong scientific leadership and hands-on execution.

Waltham, MA30+ days ago

$170,000–$200,000

This role is ideal for an engineer who thrives at the intersection of analog, highspeed digital, mixed signal, and system integration, and who enjoys solving ambiguous problems by turning constraints into clear, robust designs .   . As part of a small, highly collaborative engineering organization, you will work closely with other senior engineers to define system architectures, lead tradeoff analyses, and drive critical technical decisions.

Andover, MA15 days ago

Translate engineering design requirements into formal manufacturing process documentation including raw material definition, fixturing/tooling development, CNC programming, inspection planning, finishing requirements, and assembly instructions. Qualifications You Must Have: Typically requires a bachelor’s degree in manufacturing engineering, Mechanical Engineering, Industrial Engineering, Electrical Engineering, or Aerospace Engineering .

Watertown, MA30+ days ago

The PI performs or oversees key study assessments, reviews safety data, confirms eligibility, manages AEs/SAEs, and partners closely with clinical operations and other clinician staff. Guided by our core values—Scientific Rigor, Operational Excellence, Commitment to Sponsors and Participants, and Authentic Collaboration—we create an environment where meaningful work drives meaningful change.

Watertown, MA30+ days ago

$145,000–$215,000 Per Year

Partner closely with CMC colleagues and QA to (i) write or review test methods, SOPs, analytical data summaries (CoT/CoA), protocols, and technical reports, (ii) critically review, trend, and interpret analytical testing results, and (iii) support investigation of nonconformances (OOS/OOT results, deviations, etc.). Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.

Mansfield, Massachusetts23 days ago

Cross-functional Collaboration: Leads complex cross-functional projects to identify root causes of significant quality issues, educates stakeholders on quality requirements, and develops sustainable solutions to minimize future risks. The Principal Specialist, Quality Assurance, is a highly experienced individual contributor who applies advanced knowledge of quality assurance concepts and technical capabilities to drive uncompromised laboratory integrity and minimize risks.

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Principal Jobs in Shrewsbury, MA

Jobs

Principal Mechanical EngineerMicro Tech

Software Engineer, PrincipalDCS Corporation

Principal Manufacturing EngineerButler Aerospace and Defense

Assistant Principal (2026-2027 School Year)Rutherford County Schools

Principal Cleaning Validation EngineerPfizer

Principal Scientist (M.D. or D.O.)Exponent Inc.

Principal Manufacturing Engineer, 4th ShiftApollo Professional Solutions

Principal Systems Engineer - POC DevicesNova Biomedical

Principal Design Quality Engineer INova Biomedical

Principal Consultant - Aviation NoiseHARRIS MILLER MILLER & HANSON INC.

Principal Research Associate/Associate Scientist, Molecular AssemblyTScan Therapeutics

Pleasant Hill Elementary - PrincipalCumberland County School District

Principal Reliability EngineerRTX Corporation

Principal Systems EngineerOdyssey Systems Consulting Group, Ltd.

Principal Logistics ManagerOdyssey Systems Consulting Group, Ltd.

Principal Software EngineerOdyssey Systems Consulting Group, Ltd.

Principal DevOps EngineerVeracode

Principal Security Researcher - AIVeracode

Principal, AnalyticsTrinity Partners, LLC

Principal Logistics ManagerAstrion

Principal Software EngineerAstrion

Principal Data Links and Communications EngineerAstrion

Principal AccountantImprivata

Sr Principal R&D EngineerOlympus Corporation of the Americas

Principal Hardware Design EngineerKforce Inc.

Principal Engineer, Electrical EngineerButterfly Network

Principal Engineer, Physical ImplementationButterfly Network

Principal DevOps EngineerEvolv Technologies Inc.

Principal Research Associate - Oligonucleotide ChemistryAlloy Therapeutics

Data Security Principal ArchitectLancesoft

BAS Principal - Valuation, Financial Forensics, Litigation (VFL)LitmanGerson Associates

Principal Scientist, In Vivo Pharmacology, Oncology Discovery BiologyBristol Myers Squibb

Principal Scientist, QC Assay Automation, Cell Therapy in Devens, MABristol Myers Squibb

Principal Scientist Computational BiologyBristol Myers Squibb

Principal Technician - Infrastructure Automation EngineerCapgemini

Principal Software EngineerMondo

Principal Network EngineerAstrion

Principal Systems EngineerAstrion

BMC Remedy Application Developer PrincipalAstrion

Principal Systems Engineer - CLEARANCE REQUIREDBelcan

Principal Inventory Program ManagerCoyote Technical & Executive Sourcing

Analytical Development Principal ScientistNITTO DENKO Avecia

Principal Technical WriterNITTO DENKO Avecia

(Senior) Principal Scientist, Cell TherapyPharmaEssentia U.S.A.

Principal/ Senior Scientist – T Cell Engager & Multispecific Protein EngineeringPharmaEssentia U.S.A.

Principal Electrical EngineerEvolv Technologies Inc.

Principal Manufacturing EngineerLancesoft

Principal Investigator/PsychiatristAdams Clinical

Principal Scientist, Analytical DevelopmentKymera Therapeutics

Principal Specialist, Quality AssuranceCardinal Health

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