1,537 Results for

Principal Jobs in Watertown, MA

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Principal Digital Signal Processing Systems Engineer GCR Professional Services

Cambridge, Massachusetts

Contractor
Quick Apply

As Principal Signal Processing System Engineer you will work directly with customers and program managers to create innovative, multidisciplinary technical solutions, for a broad range of highly-complicated mission needs. You will have hands-on engagement with prototype development, which may include software or firmware coding, test equipment operation and programming, integration and validation, and field tests and customer demonstrations.

30+ days ago

Principal Software Engineer, Payer Portal Athenahealth

Boston, MA

$164,000–$280,000 / year

Based in Boston, MA with a hybrid work arrangement, this role partners with product, architecture, and engineering teams to solve complex revenue cycle challenges using distributed systems, Java, Spring Boot, AWS, Kubernetes, and related technologies. We offer IT solutions and expert services that eliminate the daily hurdles preventing healthcare providers from focusing entirely on their patients — powered by our vision to create a thriving ecosystem that delivers accessible, high-quality, and sustainable healthcare for all.

Today

Principal Systems Engineer The Computer Merchant, Ltd

Woburn, MA

$100–$110 / hour
Contractor

While an hourly range is posted for this position, an eventual hourly rate is determined by a comprehensive salary analysis which considers multiple factors including but not limited to: job-related knowledge, skills and qualifications, education and experience as compared to others in the organization doing substantially similar work, if applicable, and market and business considerations. The SE LRR department delivers cutting-edge expertise in concept development, architectural design, requirements generation and flow-down, modeling and simulation, systems analysis, integration, test, and evaluation of world-class missile defense & sensor systems.

4 days ago

Principal ML Platform Engineer - Remote Appian Corporation

Boston, MA

Remote

$175,000–$325,000 / year

Growth Opportunities: Appian provides a diverse array of growth and development opportunities, including our leadership program tailored for new and aspiring managers, a comprehensive library of specialized department training through Appian University, skills based training, and tuition reimbursement for those aiming to advance their education. Equipped with cutting-edge AI tooling, you will drive the design and delivery of high-complexity engineering solutions, set the technical bar for the team, and lead other engineers towards solutions of real complexity to ensure flawless Enterprise-Grade Orchestration.

30+ days ago

Principal Scientist, Vaccine Virology CSL Seqirus

Waltham, MA

$145,000–$180,000 / year

Techniques may include live-virus and pseudovirus neutralization, infectious-virus culture and titration, plaque and focus-forming assays, TCID50, RT-qPCR, reverse genetics, hemagglutination inhibition (HAI), microneutralization, ELISA, neuraminidase inhibition, and functional antibody assays such as antibody-dependent cellular cytotoxicity (ADCC). Reporting to the Director, Vaccine Virology & Immunology, you will provide scientific leadership and hands-on laboratory expertise to advance seasonal and pandemic influenza vaccines, support existing products, and evaluate new respiratory-virus vaccine opportunities.

6 days ago

Principal Design Engineer (Mechanical / Mechatronic) System One

Cambridge, MA

Quick Apply

Ten or more years designing precision electromechanical instruments or automated production equipment, with at least five as lead or principal designer on products that reached build and qualification. • Deep practical experience of precision fluid handling: pumps, valves, manifolds, tubing sets, connectors, seals, dead-volume and carryover control.

2 days ago

Senior Principal Scientist - Remote CSL

Waltham, MA

Remote

$179,000–$212,000 / year

Serves as a subject matter expert for cell and gene therapy and cell-based therapeutic platforms; familiarity with AAV or other viral vectors, baculovirus-based expression systems, insect cell platforms, oligonucleotides, nucleic acid-based therapeutics, or other emerging modalities is a plus. Provides expert technical input and scientific oversight for work conducted with external development and manufacturing partners, including CDMOs, CROs, technology providers, and strategic collaborators; supports technical scope definition, deliverable review, issue investigation, and risk mitigation.

1 day ago

Principal Software Engineer - Search Algorithms Elastic

Boston, MA

This is a principal software engineering role that focuses on enhancing the vector similarity search functionality within Elasticsearch, covering the design and implementation of new vector search features, enhancements to existing vector search functionality, and resolving bugs. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI.

30+ days ago

Principal Software Engineer - Storage Engine Elastic

Boston, MA

Remote

This globally distributed, fully remote team of experienced engineers develops core storage and query technologies for observability workloads, including improving storage efficiency, advancing ES|QL query processing and performance, and optimizing data layouts for object storage. By taking advantage of all structured and unstructured data — securing and protecting private information more effectively — Elastic’s complete, cloud-based solutions for search, security, and observability help organizations deliver on the promise of AI.

30+ days ago

Principal Data Engineer Waters Corporation

Milford, MA

Strong business domain knowledge and experience working with enterprise systems such as SAP (e.g., supply chain data, orders, revenue recognition, pricing), Salesforce (commercial or service processes), with the ability to translate business processes into scalable data solutions. The Principal Data Engineer designs, builds, and enhances robust data pipelines and platforms that support analytics, machine learning, and operational monitoring.

30+ days ago

Principal AI Solutions Engineer Waters Corporation

Cambridge, MA

The successful candidate will partner with scientists and engineers across the research organization to identify high-value use cases, configure AI-enabled workflows, and scale approaches that improve productivity, accelerate discovery, and increase innovation yield in domains where AI has not traditionally been applied. Waters Global Research organization advances the analytical instruments, chemistries, and software that laboratories worldwide rely on to characterize molecules with exceptional precision — from biopharmaceuticals to the safety of the food and water supply.

30+ days ago

Principal Agentic Engineer Jobot

Boston, MA

$190,000–$250,000 / year
Quick Apply

This organization takes Public Health and Patient Outcome improvements to the next level, combining the latest and greatest technologies available today to tackle the challenges faced by clinical researchers, patients, and healthcare providers nationwide. Team Health & Culture: Create an inclusive, accountable, and collaborative engineering culture where people feel empowered to make decisions, understand how their work contributes to the broader mission, and are motivated by the real-world impact of the products they build.

1 day ago

Systems Engineer, Principal - TS DCS Corp

Bedford, Massachusetts

$142,188–$190,000 / year

C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime, and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space. The MIT is responsible for translating operational requirements into technical solutions, developing integrated architectures, assessing risks, supporting acquisition execution strategies, and coordinating test and evaluation activities to ensure capabilities are delivered to operational users.

30+ days ago

Principal Manufacturing Engineer - Aerospace - Melrose, MA Michael Page USA

Melrose, MA

$150,000–$225,000 / year
Full time

They thrive in technically demanding environments, have a proven record of taking products from prototype through production, and possess the communication skills necessary to influence teams, customers, and senior stakeholders. An innovative advanced manufacturing company in the Greater Boston area is looking for a Principal Manufacturing Engineer with deep expertise in CNC machining, multi-axis programming, process development, and production scaling.

8 days ago

Assistant Principal and/or Interim Assistant Principal: Norwell Middle School Norwell Public Schools

Norwell, MA

$115,000–$130,000 / year

GENERAL DUTIES: To assist the principal in promoting learning and providing high quality administration and leadership for Norwell Middle School, particularly with student issues, safety, special education, and general administrative support. APPLICATION PROCESS: An informative letter of interest, resume, completed application form, proof of current certification or certifiability, undergraduate and graduate transcripts, and at least three (3) current letters of reference must be received at the following address no later than October 13, 2026 or until filled.

30+ days ago

Middle School Assistant Principal (Maternity Leave) North Andover Public Schools

North Andover, MA

Work with building leadership to draft and revise a comprehensive school budget for classroom teachers, specialists, and all instructional personnel assigned full-time to his/her building; prepare this budget with the assistance of teachers and system-wide administrators. Provide effective and dynamic leadership to students, faculty and families: Alongside the Principal, communicate the school''s vision, goals, long-range plans, needs, and accomplishments to students, staff, families and the community-at-large.

30+ days ago

INTERIM ASSISTANT PRINCIPAL - SWAMPSCOTT MIDDLE SCHOOL - TO COVER A LEAVE OF ABSENCE Swampscott Public Schools

swampscott, MA

This includes leading, directing, counseling, and supervising students and staff; creating effective parent, teacher, and child communications; supporting, encouraging, mentoring, and evaluating staff; fostering teamwork between teachers and among staff and parents; and managing budget items. The Middle School Assistant Principal assists the building principal in organizing and fostering a positive, safe environment that is conducive to best meeting the needs of all students, staff, and parents.

30+ days ago

Assistant Principal for the JFK Elementary School RANDOLPH PUBLIC SCHOOL DISTRICT

Randolph, MA

Work collaboratively with team chairs, Principal, central offices and families to ensure that provisions for Individual Education Programs, Progress Reports, ML processes & policies and transition plans are done in a timely and effective manner that enhances student academic, personal, social and emotional success. Be responsive to the needs and interests of all students while working in collaboration with the school principal to meet students where they are and to provide explicit support to ensure that students reach their full potential.

4 days ago

Sr Principal/Principal Software Engineer, App Lila Sciences Inc

Cambridge, MA

$204,000–$348,000 / year

Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. Communication & Collaboration: Acute listening skills, and a proven track record of working cross-functionally with scientists, data engineers, and product teams; able to explain complex ideas to diverse audiences.

30+ days ago

Interim Assistant Principal (Jan - Jun 2027) Andover Public Schools

Andover, MA

Andover Public Schools (APS) seeks candidates who embody our ethos, which includes valuing the identities of all students, high expectations for all students, teaching excellence, collaboration, innovation, respect, and responsibility. Under the general direction of the Building Principal, provides supervision and administrative leadership, and knowledge of current curriculum development and instructional techniques to assist the principal in the promoting of the educational development of each student.

13 days ago

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Principal Jobs in Watertown, MA

Principal Digital Signal Processing Systems Engineer GCR Professional Services

Principal Software Engineer, Payer Portal Athenahealth

Principal Systems Engineer The Computer Merchant, Ltd

Principal ML Platform Engineer - Remote Appian Corporation

Principal Scientist, Vaccine Virology CSL Seqirus

Principal Design Engineer (Mechanical / Mechatronic) System One

Senior Principal Scientist - Remote CSL

Principal Software Engineer - Search Algorithms Elastic

Principal Software Engineer - Storage Engine Elastic

Principal Data Engineer Waters Corporation

Principal AI Solutions Engineer Waters Corporation

Principal Agentic Engineer Jobot

Systems Engineer, Principal - TS DCS Corp

Principal Manufacturing Engineer - Aerospace - Melrose, MA Michael Page USA

Assistant Principal and/or Interim Assistant Principal: Norwell Middle School Norwell Public Schools

Middle School Assistant Principal (Maternity Leave) North Andover Public Schools

INTERIM ASSISTANT PRINCIPAL - SWAMPSCOTT MIDDLE SCHOOL - TO COVER A LEAVE OF ABSENCE Swampscott Public Schools

Assistant Principal for the JFK Elementary School RANDOLPH PUBLIC SCHOOL DISTRICT

Sr Principal/Principal Software Engineer, App Lila Sciences Inc

Interim Assistant Principal (Jan - Jun 2027) Andover Public Schools

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