Advocate Health comprises two regions in the US: (1) the Southeast Region-which provides care under the name Atrium Health in the Carolinas, Georgia, and Alabama-includes 40 hospitals and over 500 sites of care with approximately 73,000 team members, 11,000 physicians, and 20,000 nurses seeing ~2.9M unique patients; and (2) the Midwest Region-which provides care under the name Advocate Health Care in Illinois and Indiana and Aurora Health Care in Wisconsin and Michigan-includes 29 hospitals and over 500 sites of care with approximately 77,000 team members, 10,000 physicians, and 22,000 nurses seeing ~2.9M unique patients. Research excellence, coupled with a robust informatics data infrastructure, clinically integrated implementation science efforts, and a firm commitment to the promotion of health for all renders the WFUSM a rich environment for breakthroughs in prevention, diagnosis, and treatment of disease and improvements in quality of life.