Medical Director, EP, Medical and Patient Safety Gateway RecruitingMedical Director, EP, Medical and Patient SafetyBoston, MAAs the clinical voice of the physician and patient, the Global Medical Director will partner with Clinical Research, Research and Development (R&D), Quality, Regulatory Affairs and Commercial teams to support innovation, clinical evidence generation, product development and patient safety. Partner with Clinical Research, Clinical Evidence, Quality, Regulatory Affairs, R&D, Marketing and Business Development teams to support product strategy and medical decision-making.
Safety Scientist Viridian Therapeutics IncSafety ScientistWaltham, MAThe Safety Scientist collaborates primarily with the Product Safety Lead/Safety Physician for assigned products, and also with cross-functional team members to ensure active safety surveillance of SAEs and other clinical trial safety data and lead/assist in the preparation of safety-related documents. Cross-Functional Collaboration: Work closely with clinical operations, clinical development, regulatory affairs, and other departments, including the PV vendor, to ensure the safety of clinical trial participants.
Medical Director, Pharmacovigilance Viridian Therapeutics IncMedical Director, PharmacovigilanceWaltham, MARemoteThis position will partner closely with clinical development, clinical operations, biostatistics, regulatory affairs, medical affairs, quality, and external vendors/CROs to ensure high-quality, timely, and compliant safety oversight across clinical development programs, including ongoing and planned Phase 3 clinical trials. Lead or contribute to preparation of pharmacovigilance and clinical safety content for Investigator Brochures, Reference Safety Information, DSURs, PSURs/PBRERs, IND Annual Reports, clinical study reports, regulatory responses, risk management plans, and other safety-related submissions.
Medical Director, Clinical Development Dyne TherapeuticsMedical Director, Clinical DevelopmentWaltham, MA$270,000–$310,000 / yearThis role serves as the medical monitor on their assigned study(s), partnering closely with Clinical Development leadership, Clinical Operations, Pharmacovigilance, Regulatory Affairs, Biostatistics, Data Management, Translational Medicine, and other key stakeholders to support study design, protocol execution, medical review, data analysis, and regulatory deliverables. This role is responsible for ensuring participant safety, supporting high-quality study execution, interpreting emerging clinical and safety data, and providing timely medical input to study teams, investigators, vendors, and cross-functional partners.
Medical Director, Clinical Development Dyne Therapeutics IncMedical Director, Clinical DevelopmentWaltham, MA$270,000–$310,000 / yearThis role serves as the medical monitor on their assigned study(s), partnering closely with Clinical Development leadership, Clinical Operations, Pharmacovigilance, Regulatory Affairs, Biostatistics, Data Management, Translational Medicine, and other key stakeholders to support study design, protocol execution, medical review, data analysis, and regulatory deliverables. This role is responsible for ensuring participant safety, supporting high-quality study execution, interpreting emerging clinical and safety data, and providing timely medical input to study teams, investigators, vendors, and cross-functional partners.
Senior/Executive Medical Director, Medical Monitor Agenus IncSenior/Executive Medical Director, Medical MonitorLexington, MAExperience taking ownership of a clinical development program from study design through database lock, clinical study report, regulatory submission, and health authority interactions, rather than isolated experience across multiple studies. Author and/or review key technical and clinical documents, including clinical study protocols, investigator brochures, clinical study reports, annual reports, safety documents, and clinical sections of regulatory submissions.
NewDirector, Clinical Scientist - Neuroimmunology AstraZeneca PlcDirector, Clinical Scientist - NeuroimmunologyCambridge, MA$203,000–$305,000 / yearConduct AESI reviews and trending (these include CRS, neurotoxicity/ICANS, infections, IEC-HS, IEC-associated colitis, and new malignancies), prepare SRC, IDMC, and DMC safety packets, and flag emerging signals promptly with proposed next steps, bringing medical-judgement items to the Study Physician. Draft and review clinical sections of regulatory documents and responses, including HA interactions, briefing books, IND and annual reports, PIPs, and safety updates, ensuring SLMOP-driven surveillance outputs are reflected accurately and aligned with GCP, ICH, FDA, and EMA expectations.
Vice President, Global Head of Drug Safety (DS) & Pharmacovigilance (PV) Hemab ApSVice President, Global Head of Drug Safety (DS) & Pharmacovigilance (PV)Boston, MADevelop processes for and provide safety medical oversight of safety surveillance and benefit risk assessments, including medical review of ICSRs, signal management activities, safety analyses, benefit risk profile development and monitoring, and risk mitigation strategies. This role requires a hands-on leader with robust medical and operational expertise, a strong understanding of global regulatory requirements, and the ability to design and oversee a robust fit-for-purpose safety system that scales with company growth to support excellence in Drug Safety & Pharmacovigilance as a critical part of our mission.
Senior Director, Epidemiology and Real World Evidence Dyne TherapeuticsSenior Director, Epidemiology and Real World EvidenceWaltham, MA$245,000–$300,000 / yearThe Senior Director partners closely with Global Medical Directors, HEOR, Clinical Development, Biometrics, Drug Safety/Pharmacovigilance, Regulatory Affairs, Value & Access, and Commercial to generate and interpret evidence that enables asset‑level Medical Affairs strategies. Leads the design, execution, and interpretation of epidemiologic and observational studies supporting Medical Affairs objectives, including chart reviews, post hoc analyses, prospective observational studies, investigator-initiated studies, Phase 3b/4 studies, and prevalence/incidence studies.
Development Medical Director - Clinical Research Director SanofiDevelopment Medical Director - Clinical Research DirectorCambridge, MA$178,500–$297,500 / yearThe role of the DMD is to: Collaborate with other medical and clinical scientific experts DMDs or Development Scientific Directors (DSDs) in the project under the leadership of the Global Project Head, with the Global safety Officer, Regulatory Strategist and other key functional representatives to deliver development strategy and prepare/assist with regulatory bodies interaction. Provide appropriate clinical scientific input & support for all activities related to clinical studies conduct such as answers to IRBs and HA questions, protocol scientific and medical training, medical review of data within the scope of the Centralized monitoring, clinical and medical information for the study team, medical advisors/Clinical Project Leaders from Clinical Study Units, and investigators.
Clinical Research Director SanofiClinical Research DirectorCambridge, MA$206,250–$343,750 / yearProvide appropriate clinical scientific input & support for all activities related to clinical studies conduct such as answers to IRBs and HA questions, protocol scientific and medical training, medical review of data within the scope of the Centralized monitoring, clinical and medical information for the study team, medical advisors/Clinical Project Leaders from Clinical Study Units, and investigators. The role of the CRD is to: Collaborate with other medical and clinical scientific experts DMDs or Development Scientific Directors (DSDs) in the project under the leadership of the Global Project Head, with the Global safety Officer, Regulatory Strategist and other key functional representatives to deliver development strategy and prepare/assist with regulatory bodies interaction.
Senior Research Laboratory Technician Brigham and Women's HospitalSenior Research Laboratory TechnicianBoston, MA$55,712.04–$82,014.40 / yearCore activities include developing and deploying cutting edge and novel approaches for: nucleic acid isolation from human clinical specimens; digital PCR and quantitative PCR assay development; next generation sequencing (NGS) library preparation and sequencing; target enrichment (hybrid capture) with NGS; and automation of the above technologies. Massachusetts General Hospital (MGH) Clinical Microbiology Laboratory is seeking a Senior Research Laboratory Technician to support the development, optimization, and execution of high complexity molecular assays in support of clinical diagnostic development and deployment, translational research, and public health pathogen genomic surveillance.
Senior Director, Epidemiology and Real World Evidence Dyne Therapeutics IncSenior Director, Epidemiology and Real World EvidenceWaltham, MA$245,000–$300,000 / yearThe Senior Director partners closely with Global Medical Directors, HEOR, Clinical Development, Biometrics, Drug Safety/Pharmacovigilance, Regulatory Affairs, Value & Access, and Commercial to generate and interpret evidence that enables asset‑level Medical Affairs strategies. Leads the design, execution, and interpretation of epidemiologic and observational studies supporting Medical Affairs objectives, including chart reviews, post hoc analyses, prospective observational studies, investigator-initiated studies, Phase 3b/4 studies, and prevalence/incidence studies.
Clinical Scientist TScan TherapeuticsClinical ScientistWaltham, MA$145,000–$155,000 / yearThe Clinical Scientist will be responsible for leading ongoing clinical data review activities, developing data review strategies, identifying and resolving data issues, and ensuring high-quality clinical datasets are available to support safety reviews, regulatory submissions, and clinical decision-making. This unique role sits at the intersection of Clinical Development, Clinical Operations, Data Management, and Biostatistics serving as a critical driver of data quality, data integrity, and clinical insight generation.
Sr. Consultant, Quality and Compliance Syner-GSr. Consultant, Quality and ComplianceFramingham, MARemoteThis role functions as the embedded clinical quality voice for client programs: overseeing CROs and clinical vendors, auditing investigator sites and vendor systems, advising on sponsor oversight strategy, and ensuring clinical programs are inspection-ready against FDA, EMA, and ICH GCP expectations. Consultant, GCP is an experienced clinical quality professional who independently leads GCP quality and compliance engagements for Syner-G's sponsor clients — primarily virtual and emerging biotechs running Phase 1 through Phase 3 clinical programs.
Executive Director, Clinical Development Centessa Pharmaceuticals PlcExecutive Director, Clinical DevelopmentBoston, MA$340,000–$380,000 / yearReporting directly to the Vice President, Clinical Development, this leader will assume primary responsibility for the strategic and operational execution of the company's late-stage Orexin Receptor 2 Agonist Program (Program 750), which targets narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. In this highly visible, hands-on role, the Executive Director will partner closely with cross-functional teams to provide scientific and medical leadership for clinical study design, execution, data interpretation, and regulatory interactions.
Director, Pharmacovigilance Beam TherapeuticsDirector, PharmacovigilanceCambridge, MA$210,000–$260,000 / yearWork closely with the Medical/Safety Lead to support signal detection activities, which may include: preparing signal assessment, tracking, and validation documents; leading cross functional teams to assess safety signals; preparing action and communication plans to mitigate/manage product risks; responding to safety related regulatory requests; developing and maintaining product risk management plans. The Director of Pharmacovigilance will contribute to a full range of pharmacovigilance activities including but not limited to the oversight and management of safety reports and safety data, signal management activities, PV organization and process development, inspection readiness, PV vendor management, and operational support for Beam products throughout the lifecycle.
Sergeant - Public Safety Brandeis UniversitySergeant - Public SafetyWaltham, MAPhysical/Environmental Demands: Physical demands are those in excess for sedentary work; must be able to remain on feet for extended periods of time, stoop, kneel, crouch, lift, carry, push, pull, climb stairs, balance, walk, and run; must be able to access all facilities on foot; must be able to conduct visual surveillance of individuals and surroundings; must be physically able to operate and communicate using a variety of machines and equipment including baton, automobile, office equipment, radio, telephone, etc; work includes considerable exposure to unusual elements, such as severe weather/ temperatures and loud noises; work environment involves moderate exposure to hazards and physical risks to personal safety. The Sergeant manages and supervises the campus police, security staff, and parking monitors, providing 24/7 coverage for the department, to help accomplish the department's overall mission to provide a safe and secure environment all faculty, staff, students, and visitors/guests to the university and to protect life and property on and around the Brandeis campus.
Global Development Medical Director AstraZeneca PlcGlobal Development Medical DirectorBoston, MA$249,827.20–$374,740.80 / yearThe successful Study Clinical Lead in Late Phase CVRM (Cardiovascular, Renal, and Metabolic diseases) will be responsible for the design, conduct, monitoring, data interpretation and reporting of individual clinical trials ensuring that the clinical data collected within the study will allow determination of the benefits and risks of the compound, as well as will allow for the intended label indication and price in markets globally. Is accountable for ensuring that safety surveillance on a study level including the process for Adverse Events (AE)/ Serious AE reporting, the querying of missing/unclear data, the review of blinded safety data, and the escalation to the GCH/Global Safety Physician when needed.
Medical Science Liaison - Gastroenterology - Southwest SanofiMedical Science Liaison - Gastroenterology - SouthwestCambridge, MARemote$146,250–$211,250 / yearCritically and routinely evaluate and discern from the information gained from published studies, and stakeholder interactions to develop key insights that deepen our understanding of the market's needs and opinions of external stakeholders and therefore contribute to enhancement of Sanofi's scientific messages, plans, strategy, systems, and product development. The Medical Science Liaison (MSL) is field-facing role whose main objectives are to: Be the trusted scientific partner to key external experts by conducting timely, appropriate and frequent scientific exchanges to enhance the understanding of the scientific and medical value of our products.