Scientific Director, Pathology Takeda Pharmaceutical Co LtdScientific Director, PathologyBoston, MA$177,000–$278,080 / yearThis role will work with the NCSP iDigPath team to advance AI/ML applications that enable quantitative, high-content analysis of pathology data to improve sensitivity, reproducibility, and translational relevance of tissue-based endpoints to contribute to the validation of novel targets, guide the design of efficacy and safety assessment strategies, and ensure robust integration of pathology insights into program advancement and governance decisions. Accountabilities: Serve as an NCSP Project Pathologist and/or Project Toxicology representative on project teams within Global Pathology (NCSP), providing anatomic/clinical pathology and toxicology expertise and collaborating with project and cross-functional R&D leaders to support transition of programs into development.
Senior Clinical Lead, Early Clinical & Experimental Therapeutics SanofiSenior Clinical Lead, Early Clinical & Experimental TherapeuticsCambridge, MA$236,250–$393,750 / yearIn these roles, duties include: Design safe, rapid and informative First-In-Human studies for oncology assets potentially including natural history, experimental model validation, mechanistic and signal seeking, streamlined Proof-of-Mechanism as well as Proof-of-Concept studies providing robust data for early Go/No Go decisions and other pharmacokinetic studies. A key focus of this role is to support the path from the research phase through early clinical development including early and rapid Proof-of-Mechanism/Proof-of-Concept, as well as natural history studies and experimental model validation to contribute to Human Target Validation (HTV) and evaluating the pharmacology of novel therapeutic approaches.
Director / Senior Director, CMC Drug Substance Superluminal MedicinesDirector / Senior Director, CMC Drug SubstanceBoston, MassachusettsThe ideal candidate will have extensive experience in route scouting, process development, polymorphism, salt selection, crystallization, and production and solid-state development to improve solubility, stability, and PK. The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology, computational and medicinal chemistry, machine learning, and proprietary big data infrastructure.
NewDiscovery ADME Project Leader (Radioligand Therapeutics) Eli Lilly and CoDiscovery ADME Project Leader (Radioligand Therapeutics)Boston, MA$151,500–$244,200 / yearAs a Radioligand Therapeutics (bioconjugates) ADME Project Leader, bring integrated ADME subject matter expertise, driving holistic ADME strategy by aligning pharmacokinetics, metabolism, and mechanistic disposition data with early safety signals; interpret exposure-toxicity relationships, therapeutic index, and off-target liabilities to proactively de-risk programs and enable data-driven candidate selection decisions. The successful candidate will bring exceptional scientific depth, acumen, and leadership as an integral member of the project team to create bold Target Product Profiles, help establish molecule design strategy, expectations, Research Operating Plans, and partner globally, cross-functionally, and ensure teams are advancing The Right Molecule to The Right Study at The Right Time (our three R's).
NewDiscovery Adme Project Leader (Radioligand Therapeutics) Eli Lilly and CompanyDiscovery Adme Project Leader (Radioligand Therapeutics)Boston, MA$151,500–$244,200 / yearAs a Radioligand Therapeutics (bioconjugates) ADME Project Leader, bring integrated ADME subject matter expertise, driving holistic ADME strategy by aligning pharmacokinetics, metabolism, and mechanistic disposition data with early safety signals; interpret exposure-toxicity relationships, therapeutic index, and off-target liabilities to proactively de-risk programs and enable data-driven candidate selection decisions. The successful candidate will bring exceptional scientific depth, acumen, and leadership as an integral member of the project team to create bold Target Product Profiles, help establish molecule design strategy, expectations, Research Operating Plans, and partner globally, cross-functionally, and ensure teams are advancing The Right Molecule to The Right Study at The Right Time (our three R's).
Wetlands Circuit Rider Commonwealth of MassachusettsWetlands Circuit RiderSpringfield, MAEnvironmental Analyst III'',''Environmental Analyst III'',''United States-Massachusetts-Springfield-436 Dwight'',''United States-Massachusetts-Springfield-436 Dwight'',''Science'',''Science'',''Department of Environmental Protection'',''Department of Environmental Protection'',''Full-time'',''Full-time'',''Day'',''Day'',''Aug 24, 2026, 1:39:35 PM'',''Aug 24, 2026, 1:39:35 PM'',''1'',''1'',''118,661.14'',''81,059.16'',''118,661.14'',''Yearly'',''Chris Mendez / EEADiversity@mass.gov'',''Chris Under the supervision of the Regional Section Chief, the EA III will serve as Wetlands Circuit Rider and will be responsible for providing outreach and training to local conservation commissions pertaining to the implementation and enforcement of the Massachusetts Wetlands Protection Act and Regulations, and to assist in performance of all assigned duties necessary to administer the Wetlands Program including the 401 Water Quality Certification Regulations.
Environmental Analyst IV Commonwealth of MassachusettsEnvironmental Analyst IVWorcester, MAThe work will include: performing and coordinating emergency response actions; technical and administrative review of 2-hour and 72 hour notification submittals; remediation proposals and actions needed by other DEP programs; attending/conducting technical or public meetings with responsible parties, federal and state agencies and departments; overseeing field work by responsible parties of state contractors; meeting time lines, assuring compliance with applicable state and federal laws/regulations; provide technical support and training to professional staff; and perform other related duties as required. '',''Environmental Analyst IV'',''Environmental Analyst IV'',''United States-Massachusetts-Worcester - 8 New Bond St'',''United States-Massachusetts-Worcester - 8 New Bond St'',''Science'',''Science'',''Department of Environmental Protection'',''Department of Environmental Protection'',''Full-time'',''Full-time'',''Day'',''Day'',''Jul 14, 2026, 9:22:02 AM'',''Jul 14, 2026, 9:22:02 AM'',''1'',''1'',''127,235.16'',''86,434.92'',''127,235.16'',''Yearly'',''Chris Mendez / EEADiversity@mass.gov'',''Chris
Information and Data Coordinator Commonwealth of MassachusettsInformation and Data CoordinatorBoston, MAEnvironmental Analyst III'',''Environmental Analyst III'',''United States-Massachusetts-Boston-100 Cambridge Street'',''United States-Massachusetts-Boston-100 Cambridge Street'',''Science'',''Science'',''Department of Environmental Protection'',''Department of Environmental Protection'',''Full-time'',''Full-time'',''Day'',''Day'',''Aug 18, 2026, 6:00:43 AM'',''Aug 18, 2026, 6:00:43 AM'',''1'',''1'',''118,661.14'',''81,059.16'',''118,661.14'',''Yearly'',''Chris Mendez / EEADiversity@mass.gov'',''Chris Administrator of the Enforcement Response Guidance including all associated documents and policies including facilitation of communication with MassDEP enforcement leads and OGC to make sure the Enforcement Response Guidance (ERG) contains current policy changes or additions as needed.
NewScientific Director, Pathology 3316 Takeda Development Center AmericasScientific Director, PathologyBoston, MassachusettsThis role will work with the NCSP iDigPath team to advance AI/ML applications that enable quantitative, high-content analysis of pathology data to improve sensitivity, reproducibility, and translational relevance of tissue-based endpoints to contribute to the validation of novel targets, guide the design of efficacy and safety assessment strategies, and ensure robust integration of pathology insights into program advancement and governance decisions. Serve as an NCSP Project Pathologist and/or Project Toxicology representative on project teams within Global Pathology (NCSP), providing anatomic/clinical pathology and toxicology expertise and collaborating with project and cross-functional R&D leaders to support transition of programs into development.
Director of Nonclinical Safety, Cambridge, MA Isomorphic Labs LimitedDirector of Nonclinical Safety, Cambridge, MACambridge, MAAt IsoLabs, we are committed to leveraging state-of-the-art AI to advance precision medicine paradigms and establish new benchmarks for both efficacy and safety by consistently delivering the optimal treatments to the appropriate patients at precisely the right time, which we expect to significantly enhance our overall probability of success. By harnessing AI's powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drug candidates will perform in the clinic and develop medicines to treat and cure some of the world's most devastating diseases.
Director of Nonclinical Safety, Cambridge, MA Isomorphic LabsDirector of Nonclinical Safety, Cambridge, MACambridge, MAAt IsoLabs, we are committed to leveraging state-of-the-art AI to advance precision medicine paradigms and establish new benchmarks for both efficacy and safety by consistently delivering the optimal treatments to the appropriate patients at precisely the right time, which we expect to significantly enhance our overall probability of success. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drug candidates will perform in the clinic and develop medicines to treat and cure some of the world’s most devastating diseases.
Director Of Nonclinical Safety, Cambridge, MA Isomorphic LabsDirector Of Nonclinical Safety, Cambridge, MACambridge, MAAt IsoLabs, we are committed to leveraging state-of-the-art AI to advance precision medicine paradigms and establish new benchmarks for both efficacy and safety by consistently delivering the optimal treatments to the appropriate patients at precisely the right time, which we expect to significantly enhance our overall probability of success. By harnessing AI's powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drug candidates will perform in the clinic and develop medicines to treat and cure some of the world's most devastating diseases.
Principal Scientist/Associate Director, DMPK Disc Medicine IncPrincipal Scientist/Associate Director, DMPKmassachusetts, MA$186,000–$228,000 / yearPOSITION OVERVIEW: Disc Medicine's Drug Metabolism and Pharmacokinetics (DMPK) team is seeking an experienced scientist to support the application of pharmacokinetic (PK) and pharmacodynamic (PD) sciences in our drug discovery and development portfolios, with more focus on biologics programs. This role requires regular interaction with internal and external partners to ensure timely, high‑quality delivery of ADME/PKPD data and to drive DMPK strategy for both Discovery and Development programs.
AIRx, Sr. Director, Nonclinical Safety Lead Takeda Pharmaceutical Co LtdAIRx, Sr. Director, Nonclinical Safety LeadBoston, MA$212,000–$333,190 / yearYou will be embedded in the DMTA cycle from early hit assessment through IND-enabling studies, working alongside medicinal chemists, computational scientists, and biologists to flag liabilities early, design around them fast, and build the nonclinical dossier that gives programs the best possible chance in the clinic. Own the nonclinical safety strategy across the AIRx portfolio, including small molecule and biologics projects, from early screening through IND-enabling studies; ensure every program has a clear, risk-proportionate toxicology plan aligned to its clinical hypothesis and regulatory pathway.
NewAIRx, Sr. Director, Nonclinical Safety Lead 3316 Takeda Development Center AmericasAIRx, Sr. Director, Nonclinical Safety LeadBoston, MassachusettsYou will be embedded in the DMTA cycle from early hit assessment through IND-enabling studies, working alongside medicinal chemists, computational scientists, and biologists to flag liabilities early, design around them fast, and build the nonclinical dossier that gives programs the best possible chance in the clinic. Own the nonclinical safety strategy across the AIRx portfolio, including small molecule and biologics projects, from early screening through IND-enabling studies; ensure every program has a clear, risk-proportionate toxicology plan aligned to its clinical hypothesis and regulatory pathway.
Senior Manager or Associate Director, Preclinical Safety Study Monitor Kymera Therapeutics IncSenior Manager or Associate Director, Preclinical Safety Study MonitorWatertown, MA$145,000–$240,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Monitor in-life study conduct through site visits (in person or remote), in-life reviews, and routine communication with CRO study teams; review emerging study data, monitor study quality, and identify findings or quality issues requiring discussion or escalation.
Postdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (Cns) Eli Lilly and CompanyPostdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (Cns)Boston, MA$58,000–$123,200 / yearApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification; ELISA and immunoassays for protein expression and biomarker analysis; LC-MS-based quantitative bioanalysis where applicable; Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization; Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Postdoctoral Scientist – Gene Therapy Biodistribution & Molecular Biology (CNS) Eli Lilly and CompanyPostdoctoral Scientist – Gene Therapy Biodistribution & Molecular Biology (CNS)MassachusettsApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification;ELISA and immunoassays for protein expression and biomarker analysis;LC–MS–based quantitative bioanalysis where applicable;Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization;Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
Postdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (CNS) Eli Lilly and CoPostdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (CNS)Boston, MA$58,000–$123,200 / yearApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification; ELISA and immunoassays for protein expression and biomarker analysis; LC-MS-based quantitative bioanalysis where applicable; Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization; Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Project Team Leader, Biology Orum Therapeutics IncProject Team Leader, BiologyLexington, MAThis is a pivotal role that sits between hands-on execution and research leadership: you will translate strategic direction into actionable program plans, provide scientific leadership to a small team of scientists, and serve as the biology point person on cross-functional project teams. PhD in cancer biology, molecular/cell biology, pharmacology, biochemistry, or a related field, with 8+ years or a Master's degree with commensurate experience 12+ years and a demonstrated record of independently leading discovery programs.