15 Results for

Toxicology Jobs in Massachusetts

Jobs

Boston, MA30+ days ago

This is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP studies conducted at CROs) nonclinical pharmacology, PK/PD, and/or toxicology studies, in collaboration with study monitors and other scientists. The discovery toxicologist interacts directly with multidisciplinary teams including biology, medicinal chemistry, DMPK, clinical science, and outside CROs in research and/or development projects to move discovery candidates into development.

New!

Boston, Massachusetts6 days ago

This is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP studies conducted at CROs) nonclinical pharmacology, PK/PD, and/or toxicology studies, in collaboration with study monitors and other scientists. The discovery toxicologist interacts directly with multidisciplinary teams including biology, medicinal chemistry, DMPK, clinical science, and outside CRO’s in research and/or development projects to move discovery candidates into development.

New!

Cambridge, MAToday

$185,000–$260,000 Per Year

Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. Provide toxicology support for regulatory submissions and interactions with health authorities, including the authoring of nonclinical safety sections of US and international regulatory applications, and help resolve nonclinical safety queries.

Cambridge, MA18 days ago

$175,000–$260,000 Per Year

Experience designing, outsourcing, and overseeing nonclinical toxicology studies at external CROs, including international vendors; prior experience working with CROs in China (or broader APAC region) is highly desirable. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability.

New!

Boston, MAToday

$160,000–$220,000 Per Year

Antares Therapeutics is seeking an enthusiastic and self‑motivated Senior Scientist/Principal Scientist, Toxicology to join the Nonclinical Development group and support nonclinical safety assessment activities from discovery through IND‑enabling stages across the Antares pipeline. The successful candidate will play a key role in the design, execution, and interpretation of nonclinical safety studies, working both hands‑on in the laboratory and in close collaboration with external CROs.

Boston, MA11 days ago

$275,000–$300,000 Per Year

The successful candidate will work independently to direct their own program work, provide day-to-day scientific guidance to entry-level toxicology staff, and collaborate closely with peers across nonclinical and development functions. Deep expertise supporting small molecule programs across discovery, IND-enabling, and early clinical development, with demonstrated experience advancing CNS-active candidates.

Boston, MA30+ days ago

LocationNew York City, San Francisco, or BostonEmployment TypeFull timeLocation TypeHybridDepartmentScienceOverviewApplicationAt Inductive Bio we're tackling the challenge of making drug discovery more efficient. In this role, you will help shape our scientific offering, ensure that our models are rigorously validated, and guide us toward solutions that have meaningful impact in real-world drug discovery programs.

New!

Cambridge, MA2 days ago

$153,541–$230,312 Per Year

Manager level is expected to be between $131,035 and $196,553 annualized and the current base salary range for this position at the Associate Director level is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. The Global Safety Scientist will work closely with the Head of Safety Sciences and the Global Safety Leads and be responsible for leading and planning the development of aggregate safety reports, signal detection review, authoring and analyzing data for safety topic reports, and creation and update of risk management plans.

New!

Cambridge Crossing, MA4 days ago

$137,570–$166,706 Per Year

Proficient with molecular and cellular biology related techniques, including but not limited to 2D/3D/spheroid cell culture and related cellular assays, Western blot and/or JESS, qRT-PCR, flow cytometry, proliferation and/or cytotoxicity assays (CyQuant, CTG, apoptosis, IncuCyte, etc.), ELISA, MSD and/or HTRF assays, colony formation assay, processing of DNA/RNA/protein, IP/Co-IP. In addition, the individual will coordinate with other functions, such as informatics and predictive science, lead discovery and optimization, in vivo pharmacology, and translational research teams to design/execute work related to patient stratification, identification of appropriate PD markers and assay development/transfer for miniaturization, among others to ensure timely project advancement.

Cambridge, MA30+ days ago

$145,000–$177,000 Per Year

D. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. Position Overview We are seeking an enthusiastic, self-motivated Senior Scientist to join the Nonclinical Development group, supporting the nonclinical safety assessment function for IND-enabling programs across Prime Medicines pipeline.

New!

Cambridge Crossing, MA4 days ago

$252,640–$306,137 Per Year

This leader will partner deeply with Research leadership and the Pharmacology, DMPK, Toxicology, and Translational Science units to deliver the applications, workflow capabilities, AI, and supporting data flows that enable non-clinical decisions across in-vivo biology, DMPK, ADME, non-clinical safety, toxicology, and bioanalytical science. Non-clinical pharmacology generates the evidence that determines which candidates enter humans, and this role matters now because scientists need better integrated applications, AI, and workflows to generate, interpret, and act on that evidence with greater speed and confidence.

MA30+ days ago

Develop and implement cell-based and biochemical assays to assess receptor binding signaling endocytosis and trafficking to support novel ligand candidate derisking and selection. Expertise in characterizing receptor-ligand interactions and downstream cell signaling or cellular function readouts is highly desired.

New!

Cambridge, MAToday

$145,000–$177,000 Per Year

D. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.

Cambridge, MA12 days ago

$236,250–$341,250 Per Year

In these roles, duties include: Design safe, rapid and informative First-In-Human studies for oncology assets potentially including natural history, experimental model validation, mechanistic and signal seeking, streamlined Proof-of-Mechanism as well as Proof-of-Concept studies providing robust data for early Go/No Go decisions and other pharmacokinetic studies. A key focus of this role is to support the path from the research phase through early clinical development including early and rapid Proof-of-Mechanism/Proof-of-Concept, as well as natural history studies and experimental model validation to contribute to Human Target Validation (HTV) and evaluating the pharmacology of novel therapeutic approaches.

Boston, MA30+ days ago

Full-time

Propose, design, and oversee nonclinical toxicology, DMPK, and ADME studies at external CROs (GLP and non‑GLP), providing scientific oversight of protocols, execution, data interpretation, and final reports, and managing CRO relationships, timelines, and budgets. Serve as the nonclinical development lead on cross‑functional program teams, providing scientific input to development strategy, risk assessment, and decision‑making across multiple programs.

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Toxicology Jobs in Massachusetts

Director / Associate Director - Toxicology Monte Rosa Therapeutics Inc

Director / Associate Director – Toxicology Monte Rosa Therapeutics, Inc

Associate Director / Director, Toxicology Beam Therapeutics

Associate Director / Director, Toxicology Korro Bio Inc

Sr. Scientist/Principal Scientist, Toxicology (Small Molecule) Antares Therapeutics

Senior Director, Toxicology CNS Specialist Centessa Pharmaceuticals Plc

Toxicologist Inductive Bio Inc

Senior Manager/Associate Director, Global Safety Scientist, MSRM Agios Pharmaceuticals Inc

Senior Scientist, Discovery Biology Oncology Bristol-Myers Squibb Co

Senior Scientist, Safety Assessment Prime Medicine Inc

Senior Dir, In-Vivo & Non-Clinical Pharmacology Bristol-Myers Squibb Co

Scientist Investigative Sciences Alnylam Pharmaceuticals Inc

Senior Scientist, Safety Assessment Prime Medicine

Senior Clinical Lead, Early Clinical & Experimental Therapeutics Sanofi

Director, Nonclinical Development Rhythm Pharmaceuticals

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