Discovery Immunology Principal Research Scientist Vertex Pharmaceuticals, IncDiscovery Immunology Principal Research ScientistSeattle, WA$140,000–$210,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. General Summary: Vertex is seeking a highly motivated Discovery Immunology Principal Research Scientist, to lead immunology discovery programs focused on autoimmune diseases.
Associate Director, Commercial Operations Field Strategy & Execution Vertex PharmaceuticalsAssociate Director, Commercial Operations Field Strategy & ExecutionBoston, Massachusetts$164,000–$246,000 / yearServing as a critical link between strategy and execution, the Associate Director will collaborate across Commercial Operations teams and other cross-functional and technical stakeholders to ensure seamless delivery, drive business performance, and improve the overall field experience. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Director, Medical Writing (Hybrid) Vertex PharmaceuticalsDirector, Medical Writing (Hybrid)Boston, Massachusetts$192,700–$289,100 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Our Medical Writing team at Vertex is in-house, and our Writers are strategic partners in our drug development process, collaborating with cross functional teams, authoring and driving clinical & regulatory documents to bring innovative new therapies to patients.
Manager Preclinical Research Strategy and Operations Vertex PharmaceuticalsManager Preclinical Research Strategy and OperationsBoston, Massachusetts$124,000–$186,000 / yearThe ideal candidate is a highly organized and agile operations professional who thrives in a fast-paced environment, can manage multiple priorities simultaneously, and is experienced in supporting change management initiatives and driving efficiencies across cross-functional teams. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Senior Principal AI Platform Engineer, Data & AI Platform Vertex PharmaceuticalsSenior Principal AI Platform Engineer, Data & AI PlatformBoston, Massachusetts$188,000–$282,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Team Enablement – Act as a technical multiplier by providing reusable architecture patterns, starter kits, and developer-first abstractions to empower teams across Vertex to build and deploy AI solutions effectively.
Clinical Monitoring Associate Director Vertex Pharmaceuticals, IncClinical Monitoring Associate DirectorBoston, MARemote$157,200–$235,800 / yearKey Duties and Responsibilities: Manages and provides direction to CRAs and Lead CRAs, encouraging engagement, innovation and open communication while supporting Vertex and Global Clinical Operations goalsConducts Quality Oversight Visits as required to assess relationship and effectiveness of CRAs work while on site Reviews visit reports and metrics to evaluate for compliance and trends, escalating issues and involvement in the development of corrective and preventative actionsAssists in resource allocation projections/forecasting and site assignments throughout the clinical study(ies) lifecycle, ensuring proper clinical site performance and oversight is achieved; may monitor and evaluate Clinical Research Associate (CRA) and Lead CRA workloads and liaise with the Clinical Monitoring management team to ensure appropriate allocation of resources and optimal utilization and workloadContributes to developing and updating best practices and processes and provides input on discussions around quality by design and operational deliveryDevelop content and deliver training on Clinical Monitoring processes for new hire on-boarding and ongoing department training, ensuring the department is compliant with Vertex procedures, ICH-GCP and local regulationsLeads the on-time and high-quality clinical monitoring by CRAs, ensuring CRAs maintain their sites inspection ready for health authority inspections and audits at all timesRepresents Clinical Monitoring for audits/inspections as needed, leading the development of CAPA plans and investigations, ensuring inspection findings are remediated and processes are implemented within Clinical Monitoring. Education and Experience: Bachelor's degree or equivalent relevant experience requiredTypically requires 8 years of experience, including extensive Clinical Research experience with strong experience in clinical site monitoring, including a Lead CRA role, or experience working as a Project Manager, CRA Manager or equivalent, or the equivalent combination of education and experience.
Associate Director, Customer Master Lead Vertex PharmaceuticalsAssociate Director, Customer Master LeadBoston, Massachusetts$160,000–$240,000 / yearWe are seeking an execution-focused Associate Director, Customer Master to lead the Customer(HCP/HCO) master data domain within Vertex’s Enterprise Master Data Management (MDM) organization reporting to the Director, Enterprise MDM. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Center Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois) Vertex PharmaceuticalsCenter Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois)Boston, Massachusetts$122,400–$183,600 / yearThe Center Account Manager (CAM) will be responsible for achieving and maximizing territory sales goals by developing a strategic business plan, communicating thorough disease and product knowledge to healthcare professional customers (HCP’s), and utilizing effective and appropriate selling strategies. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Associate Director, Clinical Study Quality Lead (Hybrid) Vertex Pharmaceuticals, IncAssociate Director, Clinical Study Quality Lead (Hybrid)Boston, MA$160,600–$240,800 / yearOverall, the SQL is responsible for the development and execution of audit/quality plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, real-time study inspection readiness oversight, and collaboratively identifying and driving inspection preparedness strategies and activities. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Computational Genomics Research Scientist Vertex PharmaceuticalsComputational Genomics Research ScientistBoston, Massachusetts$112,000–$168,000 / yearThis Boston-based position is part of the global Data and Computational Sciences organization and will collaborate closely with research teams spanning stem cell biology, immunology, gene editing, and pre-clinical development to design studies, execute and analyze complex genomic analyses, and ultimately generate biological insights that drive early research across multiple disease programs. As an embedded computational scientist, you willbe responsible for performingbulk and single-cell sequencinganalyses, spatial transcriptomics, andmultiomicprofiling to help uncover the molecular programs that govern therapeutic cell identity, differentiation, function, and safety to accelerate the development of next-generation cell and gene therapies.
Sr. Director, Pharmacology Vertex PharmaceuticalsSr. Director, PharmacologySan Diego, California$238,900–$358,300 / yearDirector, Pharmacology will lead a department responsible for the design, development, and execution of in vitro and in vivo assays that support the progression and optimization of human therapeutics, including assays used to determine drug potency, efficacy, and mechanism of action. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Executive Assistant Vertex PharmaceuticalsExecutive AssistantBoston, Massachusetts$89,600–$134,400 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. As delegated by the executive, follows up with stakeholders at all levels to gather needed information, prompts/reminds them of critical deadlines, and helps remove any administrative roadblocks that prevent them from meeting their obligations to the executive.
Senior Director, Global Medical Affairs - Nephrology Vertex PharmaceuticalsSenior Director, Global Medical Affairs - NephrologyBoston, Massachusetts$252,000–$378,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Excellent understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with key external stakeholders (e.g., healthcare providers, payers, advocacy bodies).
Strategic Sourcing Associate Director Vertex PharmaceuticalsStrategic Sourcing Associate DirectorBoston, Massachusetts$145,600–$218,400 / yearExecution responsibilities include CGT raw materials market analysis and due diligence, supplier assessments, RFx development, negotiations, competitive price and cost analysis, financial analysis and long-term planning, contract development, ongoing supplier management, internal manufacturing site support, external contract manufacturing site support as needed, and risk management. Cross-functional Collaboration – Work closely with Development, Manufacturing, internal manufacturing sites, external manufacturing, Quality, Vendor Quality, Technical Operations, Supply Chain, Regulatory Affairs, Finance, Legal, and other functions to align sourcing activities with CGT program needs, production schedules, product specifications, supplier qualification requirements, and regulatory expectations.
Executive Director, Regulatory Strategy, Cell & Gene Therapy Vertex Pharmaceuticals, IncExecutive Director, Regulatory Strategy, Cell & Gene TherapyBoston, MA$268,200–$402,200 / yearKey Duties and Responsibilities: Leads the development of regulatory strategy for multiple projects in development (from FIH to post marketing application stage) within the T1D portfolio, representing regulatory on the senior cross-functional teams providing strategic input and innovative regulatory solutions and guidance for complex and/or critical topics. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Associate Director Medical Writing (Hybrid) Vertex PharmaceuticalsAssociate Director Medical Writing (Hybrid)Boston, Massachusetts$157,600–$236,400 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Senior Analyst, CRM Operations Vertex PharmaceuticalsSenior Analyst, CRM OperationsBoston, Massachusetts$104,000–$156,000 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. The ideal candidate will bring strong organizational, communication, and analytical skills, with a focus on leveraging AI tools and methodologies to optimize platforms, streamline governance, and improve team operations in a regulated, global environment.
Director, Agent Intelligence - HYBRID ROLE Vertex PharmaceuticalsDirector, Agent Intelligence - HYBRID ROLEBoston, Massachusetts$216,400–$324,600 / yearYou will own the four primitives that all Vertex agents are built from: agent memory (personal and organizational), personas as code, skills (atomic tools and higher-order compositions), and the flagship agents that put those primitives to work on Vertex's hardest use cases. Design, build, and deploy custom AI agents for Vertex's highest-value enterprise use cases using Snowflake Cortex AI, Databricks AI, and agent orchestration frameworks, using these builds to harden the underlying primitives.
Seattle Research Technology Associate Director Vertex PharmaceuticalsSeattle Research Technology Associate DirectorSeattle, Washington$164,400–$246,600 / yearThis role leads laboratory technology support and continuous evolution across Seattle, and is the accountable Research Site Partner for Seattle: the primary DTE relationship holder for the site's research leadership, and the front door through which site requirements are captured, shaped, and routed into the correct cross-functional platform backlog. In parallel, the role carries accountability for local technology adoption, change management, and cross-site prioritization advocacy — ensuring Seattle's voice shapes the shared platform roadmap without the site building or maintaining local one-off solutions.
Associate Director, GMP Quality CGT Personalized Medicine Vertex PharmaceuticalsAssociate Director, GMP Quality CGT Personalized MedicineBoston, Massachusetts$148,000–$222,000 / yearPartner with business and Quality system owners and digital stakeholders to provide and ensure Quality personalized medicine /advanced therapies CGT user requirements are embedded in lifecycle management projects from design through implementation and sustainment. The Associate Director, GMP Quality, CGT Personalized Medicine supports strategic design of and ensures tactical execution of quality systems, risk management, and quality culture across the Vertex Cell and Gene Therapy (VCGT) organization.