Financial Planning & Analysis Associate Director Vertex Pharmaceuticals IncFinancial Planning & Analysis Associate DirectorBoston, MA$156,000–$234,000 / yearHelp define and monitor business KPIs that support strategic decision-making and identify opportunities to expand patient access in the U.S. Knowledge and Skills: Demonstrated experience in the pharmaceutical industry, including finance business partnering with senior or executive leaders. The Associate Director will partner across Finance, Market Access, Commercial, Trade, and Analytics to deliver actionable insights, inform decision-making, and help define the key performance indicators that support business performance and patient access.
Clinical Development Associate Medical Director- Pain Vertex Pharmaceuticals IncClinical Development Associate Medical Director- PainBoston, MA$204,000–$306,000 / yearParticipates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, IND safety reports and annual reports for assigned trials, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate. Provides scientific and clinical input to study-related documents and analysis plans including informed consent forms, clinical research forms, statistical analysis plans, clinical pharmacology analysis plans, and clinical study reports.
Associate Director, Source To Contract Process & Platform Enablement Vertex Pharmaceuticals, IncAssociate Director, Source To Contract Process & Platform EnablementBoston, MA$156,000–$234,000 / yearThe AD, Source‑to‑Contract Process & Platform Enablement is responsible for leading and advancing Source‑to‑Contract (S2C) execution enablement, serving as a senior business lead for the processes, platforms, and controls that enable compliant, efficient, and scalable sourcing, contracting, and third‑party risk management. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
NewSenior Director, Head of Quality Control, T1D Mfg Ops Vertex Pharmaceuticals IncSenior Director, Head of Quality Control, T1D Mfg OpsBoston, MA$216,000–$324,000 / yearThis leader will be responsible for building and scaling a robust QC partnership model supporting complex stem cell-derived therapies across CDMOs, external testing laboratories, and commercial/clinical supply operations. This role is focused on QC network oversight, including outsourced testing governance, method transfer into external laboratories, QC scheduling and budgets, sample management strategy, assay readiness, analytical performance monitoring, and QC compliance across the external network.
Center Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois) Vertex PharmaceuticalsCenter Account Manager, Cystic Fibrosis (Midwest - Michigan and Illinois)Boston, MassachusettsThe Center Account Manager (CAM) will be responsible for achieving and maximizing territory sales goals by developing a strategic business plan, communicating thorough disease and product knowledge to healthcare professional customers (HCP’s), and utilizing effective and appropriate selling strategies. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Clinical Development Associate Medical Director-Nephrology Vertex Pharmaceuticals IncClinical Development Associate Medical Director-NephrologyBoston, MA$204,000–$306,000 / yearParticipates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, IND safety reports and annual reports for assigned trials, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate. Provides scientific and clinical input to study-related documents and analysis plans including informed consent forms, clinical research forms, statistical analysis plans, clinical pharmacology analysis plans, and clinical study reports.
Associate director, Biomarker Operational Quality (Contract) Vertex PharmaceuticalsAssociate director, Biomarker Operational Quality (Contract)Boston, Massachusetts$90–$97 / hourFull timeAgreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners. The responsibilities of this position may include, but are not limited to, the following: • Partners with appropriate quality/compliance oversight of clinical (fit-for-purpose validations and associated processes) and medical device activities across modalities in collaboration with Clinical Biomarkers and with other internal stakeholders in the business and Quality.
Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery Vertex PharmaceuticalsSenior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug DiscoveryBoston, Massachusetts$168,000–$252,000 / yearWorking at the intersection of Computational Drug Design, project teams, Data & Methods, and Digital Technology & Engineering, this individual will leverage deep expertise in computational chemistry, cheminformatics, and AI-driven drug discovery to identify high-value opportunities across the design-make-test-analyze (DMTA) cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design, knowledge synthesis, data interpretation, hypothesis generation, and decision-making. Partner with project teams and scientific leaders to develop and deploy AI co-scientists that support knowledge synthesis, SAR analysis, scientific question answering, experiment planning, virtual screening, molecular design, and lead optimization, leveraging established computational chemistry and cheminformatics approaches alongside modern AI methods.
Director, Value Realization Finance Vertex PharmaceuticalsDirector, Value Realization FinanceBoston, MassachusettsWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. The position is central to building a disciplined, consistent approach to value delivery, helping ensure strategic initiatives achieve measurable outcomes and addressing risks or variances when performance is off track.
Senior Manager, Global Revenue Technical Accounting Vertex Pharmaceuticals, IncSenior Manager, Global Revenue Technical AccountingBoston, MA$128,900–$193,300 / yearWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Enterprise Talent Management Director Vertex Pharmaceuticals, IncEnterprise Talent Management DirectorBoston, MA$181,600–$272,400 / yearThis highly visible role combines strategic thinking, data-driven decision making, and influential partnership to identify and accelerate high-potential talent, strengthen leadership readiness, and build capabilities that fuel growth. Partnering closely with senior leaders, HR Business Partners, and Centers of Excellence, you will drive enterprise talent reviews, succession planning, leadership pipeline development, executive onboarding, and senior leader development.
Immunology Senior Research Scientist - Flow Cytometry Vertex PharmaceuticalsImmunology Senior Research Scientist - Flow CytometrySeattle, Washington$124,200–$186,400 / yearThe ideal candidate is a highly motivated scientist with strong experience in multiparameter and high-dimensional flow cytometry (spectral flow), cell sorting, and immunophenotyping and a proven ability to thrive in a collaborative, fast-paced research environment. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Director, Regulatory Affairs CMC Vertex Pharmaceuticals IncDirector, Regulatory Affairs CMCBoston, MA$190,400–$285,600 / yearGeneral Summary: The Director, Chemistry Manufacturing Controls (CMC) leads a Regulatory CMC team responsible for developing and executing global regulatory strategies across multiple investigational and commercial products in the small molecule portfolio. This role provides strategic leadership for complex regulatory CMC activities, oversees Health Authority engagement, and ensures regulatory requirements are effectively integrated into development and commercialization plans.
Cybersecurity Principal Engineer - HYBRID ROLE Vertex Pharmaceuticals IncCybersecurity Principal Engineer - HYBRID ROLEBoston, MARemote$147,600–$221,400 / yearThe Principal Cybersecurity Engineer will partner closely with cybersecurity, infrastructure, cloud, application, and enterprise technology teams to strengthen security architecture, improve platform effectiveness, enhance automation, and support secure modernization efforts. The Principal Cybersecurity Engineer, Core Security Infrastructure is a technical leader responsible for shaping and advancing Vertex's core security capabilities across network, cloud, application, AI, SaaS, and hybrid environments.
Principal Engineer, VaiDA Mobile Experience Vertex Pharmaceuticals IncPrincipal Engineer, VaiDA Mobile ExperienceBoston, MA$166,640–$250,000 / yearThe ideal candidate combines strong mobile engineering expertise with a sharp eye for usability, polish, and responsiveness, and can translate complex AI-driven functionality into clear, elegant mobile interactions. This role will design and develop secure, performant, and user-friendly mobile capabilities that connect seamlessly to Vertex's AI and agentic platform, while also supporting existing mobile applications across Vertex.
Associate Director, Global Submission Management Vertex Pharmaceuticals IncAssociate Director, Global Submission ManagementBoston, MA$163,200–$244,800 / yearThis role partners closely with Major Submission Leads, Global Regulatory Strategy, Regulatory CMC, Labeling, Publishing, and Advertising & Promotion functions to support coordinated submission planning, execution consistency, and steady‑state portfolio throughput. General Summary: The Associate Director, Global Submission Management (GSM) is responsible for the strategic oversight and execution of a portfolio of global regulatory submissions across development and lifecycle programs.
Sourcing Contracts Senior Manager Vertex Pharmaceuticals IncSourcing Contracts Senior ManagerBoston, MA$132,000–$198,000 / yearAble to independently establish and maintain effective business partner relationships with stakeholders; consistently gains stakeholder respect and trust; Strong communication skills, written and verbal; able to clearly articulate opinions in concise and persuasive manner. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Clinical Development Associate Medical Director- gMG Vertex PharmaceuticalsClinical Development Associate Medical Director- gMGBoston, MassachusettsParticipates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, IND safety reports and annual reports for assigned trials, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Analytics CoE Senior Manager Vertex PharmaceuticalsAnalytics CoE Senior ManagerBoston, MassachusettsRemoteWe seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. The Senior Manager Director role is within HEOR’s Analytics Center of Excellence (CoE), a specialized team that provides strategic and technical support to HEOR, Market Access & Pricing, and the broader commercial organization.
NewAssociate Director, GMP Operational Quality (Biologics) Wed-Sat Vertex PharmaceuticalsAssociate Director, GMP Operational Quality (Biologics) Wed-SatBoston, Massachusetts$156,600–$234,800 / yearLeads a team in the Quality Operations organization responsible for internal commercial operations in support of GMP manufacturing and testing activities, including disposition of intermediates, working cell banks and clinical and commercial drug products internally at Vertex manufacturing facilities. Substantial background in managing complex projects/teams within stated objectives and timelines and with a strong understanding of the underlying business drivers; skilled at applying project management processes / tools to lead meetings, assist with project planning, and facilitate attainment of project objectives.