Associate/Laboratory Director Natera IncAssociate/Laboratory DirectorSan Carlos, CA$175,000–$280,000 / yearThe Technical Supervisor is responsible for ensuring: appropriate test method selection; adequate method verification to determine the accuracy and precision of the test; enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed; PT samples are tested in accordance with the CLIA requirements; PT results are returned within the time frames established by the PT program; PT reports are reviewed by the appropriate staff; corrective action plans are followed when PT results are found to be unacceptable or unsatisfactory; quality assessment and quality control programs are established and maintained; acceptable analytical test performance is established and maintained for each test system; remedial actions are taken and documented when significant deviations from the laboratory's established performance characteristics are identified, and patient test results are reported only when the system is functioning properly; personnel have been appropriately trained and demonstrate competency prior to testing patient specimens; policies and procedures are established for monitoring personnel competency in all phases (preanalytic, analytic, and postanalytic) of testing to assure the ongoing competency of all individuals who perform testing; remedial training or continuing education needs are identified, and training provided; and an approved procedure manual is available to all personnel. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
Associate Laboratory Director Natera IncAssociate Laboratory DirectorSan Carlos, CA$158,200–$197,800 / yearThe Technical Supervisor is responsible for ensuring: appropriate test method selection; adequate method verification to determine the accuracy and precision of the test; enrollment of the laboratory in a CMS-approved proficiency testing (PT) program for the test performed; PT samples are tested in accordance with the CLIA requirements; PT results are returned within the time frames established by the PT program; PT reports are reviewed by the appropriate staff; corrective action plans are followed when PT results are found to be unacceptable or unsatisfactory; quality assessment and quality control programs are established and maintained; acceptable analytical test performance is established and maintained for each test system; remedial actions are taken and documented when significant deviations from the laboratory's established performance characteristics are identified, and patient test results are reported only when the system is functioning properly; personnel have been appropriately trained and demonstrate competency prior to testing patient specimens; policies and procedures are established for monitoring personnel competency in all phases (preanalytic, analytic, and postanalytic) of testing to assure the ongoing competency of all individuals who perform testing; remedial training or continuing education needs are identified, and training provided; and an approved procedure manual is available to all personnel. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
Senior Director, Disease Biology Arc InstituteSenior Director, Disease BiologyPalo Alto, CA$263,500–$325,500 / yearAlongside that build, this leader will direct Arc's existing in vivo and advanced cellular model teams to identify and validate novel targets, partnering with Arc's computational technology center to apply causal modeling and assemble a prioritized portfolio. Partner with computational biology and machine learning teams to surface new pathway insight, apply causal modeling to test target hypotheses, and draw on patient genetics and sample databases to validate and prioritize candidates.
Computational Scientist (Biology) AxiomComputational Scientist (Biology)San Francisco, CaliforniaThis creates a compounding loop: deeper customer understanding shapes the data we generate; better data improves frontier models, Axiom’s fine-tuned models, and our agentic infrastructure; stronger models and tooling expand the capabilities we can offer; and those capabilities are forward deployed into pharma's drug discovery workflows, where scientists use them to solve the highest value drug discovery problems. Analyze high-content imaging and transcriptomic data from primary human hepatocytes and multicellular hepatic systems, including phenotypes related to mitochondrial dysfunction, cholestasis, lipid accumulation, lysosomal stress, ER stress, cytotoxicity, and cellular morphology.
Executive Director, Computational Systems Biology Revolution Medicines, Inc.Executive Director, Computational Systems BiologyRedwood City, CA$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Research Associate, Discovery Biology Assembly Biosciences, Inc.Research Associate, Discovery BiologySouth San Francisco, CA$87,000–$91,260 / yearsterile technique, maintenance of mammalian cells, cytotoxicity, virus production and titration, transporter & reporter assays, antiviral activity assays & mechanism of action studies; ELISA, (RT)qPCR; molecular cloning; transfection; Western blot; etc. Assembly Bio (NASDAQ: ASMB) is an ambitious biopharmaceutical company with cutting-edge therapeutic candidates capable of improving the lives of millions living with devastating viral and liver diseases.
Regional Biology Lead BKFRegional Biology LeadWalnut Creek, CA$153,691–$187,845 / yearSupport clients in need of environmental permitting, including but not limited to Incidental Take Permits, Habitat Conservation Plan Drafting and consistency analyses, Clean Water Act 401 and 404 permits, California Coastal Commission permits, and CDFW Section 1600 permitting. In the event a recruiter or agency submits a resume or candidate without a previously signed agreement and a specific solicitation for the position or other approved engagement request for the position with BKF Engineers, BKF Engineers reserves the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency.
Member of the Technical Staff, Phenomics and High-Throughput Biology ConquestMember of the Technical Staff, Phenomics and High-Throughput BiologyPalo Alto, CaliforniaA big part of this role is workflow automation in the truest sense: figuring out what a skilled human currently does at the bench, understanding why it works, and then re-engineering it so a robot does it reliably at scale. You'll design experiments in oncology cell models, push them toward high-throughput, and work directly with our computational and AI team to make sure the data we generate is worth learning from.
Member of Technical Staff, Experimental Biology Radical NumericsMember of Technical Staff, Experimental BiologySan Francisco, CaliforniaWe are looking for someone who can move fluidly between scientific strategy and execution: understanding what question we're trying to answer, designing the right experiment, getting it run quickly and rigorously, interpreting what happened, and turning the result into the next modeling or experimental decision. You'll design experiments to test ideas generated by our models, identify and manage the CROs and external laboratories that can execute them, interpret the resulting data, and work directly with our research teams to decide what to build next.
Executive Director, Computational Systems Biology Revolution MedicinesExecutive Director, Computational Systems BiologyRedwood City, California$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. Cross-functional collaboration across research, translational, development and medical affairs groups: Work across functions to support advancement of programs from early discovery into clinical development using biological insights derived from computational approaches.
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)South San Francisco, CA$147,800–$274,400 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Research Associate, Discovery Biology Assembly Biosciences IncResearch Associate, Discovery BiologySouth San Francisco, CA$87,000–$91,260 / yearDeveloping, optimizing, and validating biochemical and cell-based assays to support ongoing discovery projects In collaboration with senior research member, making detailed observations, analyzing data, and interpreting results Effectively supporting multiple projects and learning new techniques to support novel exploratory discovery work, as needed Presenting experimental findings, assay results, and scientific rationale clearly to internal project teams to support data-driven decision-making Utilizing data analysis software and MS Office applications Managing compound inventories and assay data Participating in general lab maintenance including reagent preparation, ordering of general lab supplies, and maintenance of equipment. Qualifications Include: Sc./M.S. or equivalent degree in Cell Biology, Molecular Biology, Virology, or relevant scientific discipline Minimum of two (2) years of relevant experience in industrial or academic settings, preference given to experience in a drug discovery setting Strong expertise in assay development, cell biology, virology, and molecular biology techniques, e.g.
Executive Director, Computational Systems Biology Revolution Medicines IncExecutive Director, Computational Systems BiologyRedwood City, CA$265,000–$331,000 / yearThe individual will lead a team of computational biologists and bioinformaticians focused on acquisition, organization, and analysis of large multi-omics data sets, using both public and proprietary data sources, that will help inform treatment strategies and guide patient stratification for a growing pipeline of RAS(ON) and targeted oncology therapeutics. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Scientist/Sr. Scientist, Chemical Biology General ProximityScientist/Sr. Scientist, Chemical BiologySan Francisco, MississippiYour responsibilities will include: supervising synthetic efforts with our CROs, designing, performing, and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas. Experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen).
Scientist, Mechanistic Biology General ProximityScientist, Mechanistic BiologySan Francisco, MississippiYour responsibilities will include designing and executing mechanistic studies on hit compounds, dissecting signaling pathways to map compound mechanism of action, interrogating protein-protein interactions, preparing and analyzing NGS libraries, and developing and deploying functional cell-based assays to characterize novel pharmacology. Strong experience with : Cellular and molecular biology, including extensive experience with mammalian cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning, etc.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related) Amgen Inc.Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related)South San Francisco, CA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)South San Francisco, CA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Senior Computational Scientist – Systems Biology & Next‑Gen Data Engineering CalliereSenior Computational Scientist – Systems Biology & Next‑Gen Data EngineeringUnion City, CaliforniaYou’ll join a tight-knit team of scientists and engineers decoding huge multi‑omic datasets to uncover patterns that actually change patient outcomes. If you’re driven by the idea of building tools that help decode biology at scale and you thrive where data meets diagnostics, this is your stage.
Senior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT)South San Francisco, CA$168,100–$312,300 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact.
Senior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT) Genentech IncSenior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT)South San Francisco, CA$147,800–$274,400 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. We are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology group in the Department of AI for Biology & Translation (AIBT) in Genentech Research and Early Development (gRED).