NewAssociate Director / Director, Quantitative Systems Pharmacologist Lead GSK plcAssociate Director / Director, Quantitative Systems Pharmacologist LeadWaltham, MA$188,100–$313,500 / yearSought after experiences for this position include building mechanistic mathematical models and leveraging knowledge in the areas of scientific ML, inverse problems, AIML and/or statistical methodologies, to enhance the robustness and quality of model development to leverage for decision-making from exploratory research through clinical development. In addition, you will be defining, implementing and coordinating QSP and QST related Clinical Pharmacology and Quantitative Medicine development strategies for disease and therapeutics of interest, and providing expert input into the clinical pharmacology evidence generation and integrated evidence plans in the Disease therapeutic area.
In Vitro Pharmacologist - Molecule Discovery Eli Lilly and CoIn Vitro Pharmacologist - Molecule DiscoveryBoston, MA$163,500–$281,600 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). They will also serve as a key ExploR&D scientific expert and consultant to biotechs, designing and executing fit-for-purpose in vitro pharmacology models to support hit selection, lead optimization, and candidate progression in partnership with biotechs, and will evaluate and build CRO networks to support and extend these capabilities.
Pharmacometrician & Systems Pharmacologist Pfizer IncPharmacometrician & Systems PharmacologistCambridge, MA$106,000–$176,600 / yearSubject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. The Pharmacometrics & Systems Pharmacology (PSP) group is seeking a highly motivated quantitative scientist to support the Internal Medicine portfolio through the application of model-informed drug development (MIDD).
Director, Head of Program Management Tessera Therapeutics IncDirector, Head of Program ManagementSomerville, MA$186,000–$239,000 / yearCompany Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Guiding and empowering Program Managers to drive the development and management of integrated program plans (including timelines, assumptions, scenarios, risks, critical path, decision maps, goals, and budget drivers).
Head of Translational Science Absentia LabsHead of Translational ScienceBoston, MassachusettsThey will be responsible for ensuring that our platform addresses the highest-value problems in drug development, generates evidence that customers trust, and evolves in ways that support adoption across pharmaceutical, biotechnology, and regulatory organizations. We are seeking a hands-on leader capable of connecting science, product, regulatory strategy, and customer needs to help define the adoption of AI-native safety assessment across the global drug development ecosystem.
Director, Clinical Pharmacology Crescent BiopharmaDirector, Clinical PharmacologyWaltham, Massachusetts$226,000–$250,000 / yeardiv> #LI-CBIO
Senior Director, Clinical Pharmacology Vertex PharmaceuticalsSenior Director, Clinical PharmacologyBoston, MassachusettsAs a Disease Area leader, the Senior Director, Clinical Pharmacology will direct Clinical Pharmacology efforts for small molecule, large molecule, and novel modality programs, such as gene editing, gene therapy, and cell therapy, in the Disease Area. The role’s responsibilities will include maintaining organizational processes across the group, influencing clinical program strategy, and integrating activities with other departments across the Global Research and Development organization, to help shape innovative and integrated clinical development plans.
NewExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and Simulation GSK plcExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and SimulationWaltham, MAThe incumbent will act as a subject matter expert, working closely with the VP, Head of Oncology Clinical Pharmacology, Modeling and Simulation and the Oncology Translational Medicine leadership to provide scientific leadership in trial design, data interpretation, and aid in global harmonization of pre-clinical execution and reporting. input on development of efficient and effective modeling and simulation strategies, including population PK, exposure-response analysis, and physiologically based PK (PBPK) to support clinical trial design, justification of dosing regimen, and provide supportive evidence of efficacy and safety for regulatory submissions.
Director, Clinical Pharmacology Alkermes PlcDirector, Clinical PharmacologyWaltham, MAIn 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
Pioneering Medicines: Vice President / Senior Vice President - Head of Biology Invitro and InVivo Pharmacology Flagship Pioneering IncPioneering Medicines: Vice President / Senior Vice President - Head of Biology Invitro and InVivo PharmacologyCambridge, MA$252,000–$410,000 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company's annual list of the World's Most Innovative Companies. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Sr. Scientist, DMPK Centessa Pharmaceuticals PlcSr. Scientist, DMPKBoston, MA$160,000–$180,000 / yearCentessa is seeking a Senior Scientist in Discovery DMPK to partner with pharmacologists and medicinal chemists to support the identification of lead candidates with optimal DMPK properties for potential progression into development. Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts.
Associate Director, Discovery DMPK Parabilis MedicinesAssociate Director, Discovery DMPKCambridge, MA$165,000–$200,000 / yearIts lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between ß-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/ß-catenin-driven tumors. Reporting to the VP of Discovery DMPK, you will serve as the primary DMPK representative on cross-functional discovery project teams, collaborating closely with medicinal chemists, pharmacologists, toxicologists and external CRO partners to advance novel therapeutics from early discovery through DC nomination.
NewHistology and 3D In Vitro Models Scientist Eurofins Scientific SEHistology and 3D In Vitro Models ScientistCambridge, MA$100,000–$105,000 / yearp>Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier, and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic, and labelling is accurate.
Director, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas) Novartis AGDirector, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas)Cambridge, MA$185,500–$344,500 / yearInternal Title: Director #LI-Hybrid Location: Cambridge, MA USA In this key role you will provide global, end to end nonclinical safety leadership across multiple therapeutic areas and modalities, ensuring scientifically robust, fit for purpose, and regulatory compliant safety strategies that enable successful clinical trial initiation and support registration. You will be a critical enabler of portfolio progression, providing authoritative nonclinical safety leadership, regulatory credibility with Health Authorities, and strategic integration across therapeutic areas and modalities.
Clinical Research Director - Rare Diseases SanofiClinical Research Director - Rare DiseasesCambridge, MA$178,500–$257,833.33 / yearp>Experience / Skills: MD or MD/PhD in a relevant scientific discipline, preferably pulmonology, with at least 2 years relevant experience in clinical development within the pharmaceutical industry, academia, or government agencies such as the NIH, FDA, or other equivalent national or international public health and regulatory organization. On Clinical Development, the CRD: Designs the global clinical development strategy (in close cooperation with other members of the team, particularly Regulatory Affairs end Health Economics) and leads the clinical development with regard to ongoing development activities and planned LCM for labelling changes.