NewScientist I, Imaging and Pharmacology Perceptive Informatics LLCScientist I, Imaging and PharmacologyNeedham, MA$65,305–$121,287 / yearBachelor's degree in Biology, Animal Science, or related field, with 7+ years of relevant in vivo research experience or higher degree with 5+ years of relevant in vivo research experience. This role is central to our preclinical research team and involves hands-on work with nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI).
Principal Scientist, Cell Pharmacology Parabilis MedicinesPrincipal Scientist, Cell PharmacologyCambridge, MA$160,000–$190,000 / yearWe are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options. Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered undruggable.
Pharmacology Research Associate BiocytogenPharmacology Research AssociateWaltham, MassachusettsDevelop, perform, interpret, and troubleshoot a broad range of in vitro assays including immune cell profiling, cytokine profiling, functional assays using primary cells, as well as cytotoxicity/apoptosis assays using primary and/or cultured cells. Its service platform integrates preclinical studies with innovative animal models, CRISPR-based gene editing, and animal supplies, with the current focus on immuno-oncology and oncology.
Executive Director, Toxicology Centessa Pharmaceuticals, LLCExecutive Director, ToxicologyBoston, MA$270,000–$300,000 / yearServe as the primary nonclinical representative on Program Development Teams (PDTs) and at internal governance and external forums, effectively championing program strategy, presenting to regulatory authorities, and holding scientific ground with senior leadership, partners, CROs, and health authorities. Lead nonclinical sub‑teams as an integrated development head, providing cross‑functional oversight across Toxicology, DMPK, Bioanalytical Sciences, and Clinical Pharmacology to ensure aligned, program‑ready nonclinical strategies.
Senior Director, Toxicology (CNS Specialist) Centessa Pharmaceuticals, LLCSenior Director, Toxicology (CNS Specialist)Boston, MA$275,000–$300,000 / yearThe successful candidate will work independently to direct their own program work, provide day-to-day scientific guidance to entry-level toxicology staff, and collaborate closely with peers across nonclinical and development functions. Deep expertise supporting small molecule programs across discovery, IND-enabling, and early clinical development, with demonstrated experience advancing CNS-active candidates.
Senior Director, Toxicology CNS Specialist Centessa Pharmaceuticals PlcSenior Director, Toxicology CNS SpecialistBoston, MA$275,000–$300,000 / yearThe successful candidate will work independently to direct their own program work, provide day-to-day scientific guidance to entry-level toxicology staff, and collaborate closely with peers across nonclinical and development functions. Deep expertise supporting small molecule programs across discovery, IND-enabling, and early clinical development, with demonstrated experience advancing CNS-active candidates.
Executive Director, Head of Toxicology Centessa Pharmaceuticals PlcExecutive Director, Head of ToxicologyBoston, MA$320,000–$350,000 / yearServe as the primary nonclinical representative on Program Development Teams (PDTs) and at internal governance and external forums, effectively championing program strategy, presenting to regulatory authorities, and holding scientific ground with senior leadership, partners, CROs, and health authorities. Lead nonclinical sub‑teams as an integrated development head, providing cross‑functional oversight across Toxicology, DMPK, Bioanalytical Sciences, and Clinical Pharmacology to ensure aligned, program‑ready nonclinical strategies.
Senior Director, Toxicology (Cns Specialist) Centessa Pharmaceuticals PlcSenior Director, Toxicology (Cns Specialist)Boston, MA$250,000–$270,000 / yearThe successful candidate will work independently to direct their own program work, provide day-to-day scientific guidance to entry-level toxicology staff, and collaborate closely with peers across nonclinical and development functions. Deep expertise supporting small molecule programs across discovery, IND-enabling, and early clinical development, with demonstrated experience advancing CNS-active candidates.
Executive Director, Toxicology Centessa Pharmaceuticals PlcExecutive Director, ToxicologyBoston, MA$270,000–$300,000 / yearServe as the primary nonclinical representative on Program Development Teams (PDTs) and at internal governance and external forums, effectively championing program strategy, presenting to regulatory authorities, and holding scientific ground with senior leadership, partners, CROs, and health authorities. Lead nonclinical sub‑teams as an integrated development head, providing cross‑functional oversight across Toxicology, DMPK, Bioanalytical Sciences, and Clinical Pharmacology to ensure aligned, program‑ready nonclinical strategies.
(StealthCo) Scientist: Biology and Cell Pharmacology Foresite Labs(StealthCo) Scientist: Biology and Cell PharmacologyBoston, MAThe position is a rare opportunity to play a pivotal role in the successful development of new drugs for patients within an early-stage therapeutics company backed by highly regarded investors. The successful candidate will be mechanistically minded, able to connect experimental observations to underlying biology, build novel reproducible assays, and deliver results in a fast-paced environment.
NewScientist I, Imaging and Pharmacology PerceptiveScientist I, Imaging and PharmacologyNeedham, MassachusettsBachelor’s degree in Biology, Animal Science, or related field, with 7+ years of relevant in vivo research experience or higher degree with 5+ years of relevant in vivo research experience. This role is central to our preclinical research team and involves hands-on work with nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI).
Principal Scientist I or II, PK Sciences Therapeutic Areas (Multiple Listings) Novartis AGPrincipal Scientist I or II, PK Sciences Therapeutic Areas (Multiple Listings)Cambridge, MA$108,500–$201,500 / yearA minimum of 0-2 years of experience in drug discovery and/or development in a relevant environment (academia, CRO, biotech or Pharma).• 2+ years of experience preferably in a lead role overseeing ADME/DMPK project strategy, either in discovery or clinical development to be considered for Principal Scientist II• Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.• • Works in close collaboration with clinicians and clinical development colleagues to integrate PKS insights into study design, data interpretation, and project decision‑making• Use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, authoring regulatory documents, and the use of predictive modelsThis role reports to Therapeutic Area group in PK Sciences within Translational Medicine (TM) in Biomedical Research.
Principal Biologist ProximaPrincipal BiologistBoston, MassachusettsThis is a hands-on role: you'll run select assays in-house, manage CROs, and work closely with our structural proteomics data generation platform and computational teams, helping shape how our platform is applied to proximity-based drug discovery. You'll work across the full discovery arc, from target validation through hit ID, hit-to-lead, and lead optimization, owning the cellular pharmacology data that drives internal pipeline decisions and external partner deliverables.
Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia CorpSenior/Principal Scientist, MPN Biology, Translational SciencesBEDFORD, MASummary of Key Responsibilities: Study Design and Execution: Lead the design, planning, and execution of POC and translational studies in healthy and MPN mouse models and primary human cellular and tissue systems to generate comprehensive pharmacology and biomarker data packages including MOA and differentiation from competitor programs. Founded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.
Director, Exploratory Research Rhythm PharmaceuticalsDirector, Exploratory ResearchBoston, MA$182,000–$275,000 / yearThis role offers an opportunity to drive new scientific directions, contribute to pipeline evolution, and serve as a scientific leader while working closely with the broader Research team to generate high-impact scientific insights that bring transformative therapies to patients with rare neuroendocrine diseases. Reporting to the VP, Nonclinical Research, this individual will play a critical role in identifying and validating high-value opportunities for pipeline expansion and lifecycle management, deepening understanding of Rhythm's assets and indications, and supporting portfolio programs.
Distinguished Scientist, Safety Assessment Project Expert SanofiDistinguished Scientist, Safety Assessment Project ExpertCambridge, MA$178,500–$257,833.33 / yearThese activities entail formulating the nonclinical safety strategies, designing safety pharmacology and toxicology studies, authoring regulatory documents, being a member of an integrated Project Team, interacting with internal and external partners, and interacting with and responding to global regulatory agencies. Our Team: The candidate will be part of a dynamic interactive Preclinical Safety group that spans all aspects of the drug development value chain providing toxicology and safety pharmacology expertise as a member of global project teams.