Pace Analytical Life SciencesNewAnalytical Development Scientist Pace Analytical Life SciencesAnalytical Development ScientistWoburn, MA$95,000–$140,000 / yearPace Life Sciences is a premier Contract Research and Development Organization located just north of Cambridge, MA providing pharmaceutical research and development services for small molecules, protein biologics, oligonucleotide and mRNA therapeutics, and other innovative drug candidates. Optional: hands-on experience in multiple chromatography (SEC, IEX, & IPRP HPLC/UPLC), spectroscopy (UV, CD), mass spectrometry (LC-MS, LC-MS/MS), and electrophoresis (CGE, PAGE) technologies.
Net2SourceNewResearch Scientist - CardioMetabolic Research Net2SourceResearch Scientist - CardioMetabolic ResearchBoston, MA$74.83–$88.04 / hourThe ideal candidate should possess a solid background in cell culture and cell-based functional assays, playing an essential role in advancing our discovery initiatives and pipeline projects centered on anti-obesity therapeutics. • Development of cell-based functional assays, biochemical and enzymatic assays and screening of Client therapeutics in 96-/384-well plate formats at a single concentration or in a concentration/response manner.
Boston UniversityPostdoctoral Associate, Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of Medicine Boston UniversityPostdoctoral Associate, Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of MedicineBoston, MA$65,000–$70,000The core program is to translate AD genetics and functional genomics into human brain cells both in vitro 2D and 3D models using human induced pluripotent stem cells (hiPSCs) from population and isogenic lines generated by CRISPR/Cas9 genome editing and in vivo hiPSC/rodent chimera systems in comparison with post-mortem brain. The TCW laboratory (https://sites.bu.edu/tcwlab/) in the Department of Pharmacology, Physiology & Biophysics at Boston University Chobanian & Avedisian School of Medicine in Boston, Massachusetts is looking for highly motivated and skilled stem cell biologists or electrophysiologists to be the drivers of our efforts to translate the genetics of human AD toward therapeutic interventions.
Integrated Resources, IncBiologist Integrated Resources, IncBiologistBoston, MAThe ideal candidate should possess a solid background in cell culture and cell-based functional assays, playing an essential role in advancing our discovery initiatives and pipeline projects centered on anti-obesity therapeutics. Development of cell-based functional assays, biochemical and enzymatic assays and screening of Client therapeutics in 96-/384-well plate formats at a single concentration or in a concentration/response manner.
MEDICILON USA CORPSenior Scientist, Pharmacology (Flow Cytometry) – Contract-to-Hire MEDICILON USA CORPSenior Scientist, Pharmacology (Flow Cytometry) – Contract-to-HireLexington, MAThe ideal candidate is a hands-on scientist who can independently design and execute studies, troubleshoot complex assays, and communicate scientific findings clearly to both internal teams and external clients. Medicilon is seeking a highly motivated Senior Scientist to support our Pharmacology and Biology team, with a strong focus on in vitro and ex vivo assay development, flow cytometry, and immunology-based platforms.
ALS TDINewScientist I or II, In Vivo Pharmacology, Drug Discovery ALS TDIScientist I or II, In Vivo Pharmacology, Drug DiscoveryWatertown, MAThe ALS Therapy Development Institute (ALS TDI) is the world's leading nonprofit biotech focused exclusively on discovering and developing effective treatments for amyotrophic lateral sclerosis (ALS). This position is responsible for developing new animal models of ALS and performing preclinical pharmacology studies to evaluate the safety, efficacy, and mechanism of action of experimental drugs.
PharmaEssentia U.S.A.Senior / Principal Scientist, Immunology & Pharmacology PharmaEssentia U.S.A.Senior / Principal Scientist, Immunology & PharmacologyBEDFORD, MAFull timePharmaEssentia Innovation Research Center (PIRC) is expanding its drug discovery organization in the Greater Boston area and is seeking an experienced and highly motivated Senior or Principal Scientist with expertise in immunology, immuno-oncology, and translational pharmacology. Cross-Functional CollaborationWork effectively within multidisciplinary teams spanning biologics discovery, translational science, bioinformatics/data science, and external CRO collaborators.
Alloy TherapeuticsAssociate Scientist, In Vitro Pharmacology Alloy TherapeuticsAssociate Scientist, In Vitro PharmacologyWaltham, MAFull timeYou will report to the Associate Director, In Vitro Pharmacology and will work collaboratively in a matrixed environment to drive biologics discovery while supporting rapid decision-making in a fast-moving biotech setting. As Alloy Tx enters its next phase of growth, we are expanding our capabilities to include mechanistic studies that enhance preclinical development and further advance our translational research efforts.
Alloy TherapeuticsScientist I/II, In Vitro Pharmacology Alloy TherapeuticsScientist I/II, In Vitro PharmacologyWaltham, MAFull timeYou will report to the Associate Director, In Vitro Pharmacology and will work collaboratively in a matrixed environment to drive biologics discovery while supporting rapid decision-making in a fast-moving biotech setting. Execute cell-based functional assays using high-throughput approaches in primary cells, immortalized reporter cell lines, and other disease-relevant cellular systems.
TalentBurst, Inc.Clinical/Development - Scientist TalentBurst, Inc.Clinical/Development - ScientistCambridge, MAQualifications PhD in Chemistry, Biochemistry or related disciplines with 1-4 years industry experience, Master's degree with > 6 years related industry experience or Bachelor's degree with > 10 years related industry experience respectively, with demonstrated chromatographic separation, method development / qualification and structure elucidation expertise. Key Responsibilities Develop, qualify, and troubleshoot chromatographic (GC, HPLC/UPLC) and LCMS based methods for the identification, characterization, and impurity profiling of oligonucleotides, siRNAs, and their formulations, as well as raw material related analytical methods and other methods as needed.
DynamiCure BiotechnologySenior Research Technician DynamiCure BiotechnologySenior Research TechnicianWaltham, MAFull timeCandidates should be reliable self-starters who embrace a high level of ownership over their work, a can-do attitude, and a collaborative, team-centered approach to support our efforts to accelerate biological discovery and the development of new therapeutics. Driven by science and passionate about advancing patient care, we are translating potentially revolutionizing new insights on immuno-normalization into a pipeline of innovative antibody candidates with first-in-class and best-in-class potential.
DynamiCure BiotechnologySenior Scientist, In Vitro Pharmacology DynamiCure BiotechnologySenior Scientist, In Vitro PharmacologyMA, MAFull timeBroad skillset for target validation, potency evaluation and MoA interrogations is highly desired, including the use of tissue culture approach with multiple readouts, flow cytometry, ex-vivo studies, use of gene knockdown tools, conventional immunoassays, phosphorylation analysis and conventional pulldown assays. Extensive experience working with different types of in vitro systems such as immune cells, epithelial cells, fibroblasts, endothelial cells, and other cell lines.