The OHARO OHRO is responsible for ensuring that USAMRDC conducts, contracts, sponsors, supports or manages research, and U.S. Army Medical Command investigations involving human subjects, human anatomical substances or animals are conducted in accordance with Federal, DoD, Army, USAMRDC, and international regulatory requirements. HSP AS contractor duties include completing HRPO protocol submission reminder correspondence, managing protocol records, updating databases used to track submission information, preparing correspondence related to protocol reviews, and compiling reports on HRPO reviews as requested.