Associate Director, Toxicology Denali Therapeutics IncAssociate Director, ToxicologySouth San Francisco, CA$171,000–$223,000 / yearDenali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine.
Associate Director Toxicology Acadia Pharmaceuticals IncAssociate Director ToxicologySan Francisco, CA$155,000–$193,200 / yearKnowledge in the tools and procedures of preclinical safety assessment/toxicology experimentation, including the various experimental designs, statistical tools of data analyses, software applications available for data manipulation and presentation, and instrumentation pertinent to the research and ability to evaluate the advantages and disadvantages of each, in terms of applicability to the research at hand. We are developing the next wave of therapeutic advancements with a robust and diverse pipeline that includes mid- to late-stage programs in Alzheimer's disease psychosis and Lewy body dementia psychosis, along with earlier-stage programs that address other underserved patient needs.
Director/Senior Director, Toxicology GalapagosDirector/Senior Director, ToxicologySan Francisco, CALakefront Biotherapeutics is a global biotech with offices in Belgium, Chicago and San Francisco, focused on building a differentiated immunology and inflammation pipeline to address serious diseases with high unmet medical need. Design, oversee, and interpret GLP and non-GLP toxicology studies including single- and repeat-dose tox, genotoxicity, reproductive and developmental toxicology, carcinogenicity, and safety pharmacology.
Director, Toxicology Pliant Therapeutics IncDirector, ToxicologySouth San Francisco, CAThis role provides strong scientific and intellectual leadership across cross-functional teams, partners closely with internal stakeholders and external vendors, and represents nonclinical safety in interactions with global regulatory authorities. We believe our platform may be broadly applicable across multiple disease areas including delivery of drug payloads to cells utilizing integrin receptor-binding molecules as tissue-specific delivery and internalization mechanisms.
Toxicology Management Specialist (San Francisco, CA) UCSF Medical CenterToxicology Management Specialist (San Francisco, CA)San Francisco, CAMinimum of 2 years of experience in clinically-oriented pharmacy practice OR 2 years prior Poison Control Center experience or an equivalent combination of education and experience; and knowledge and ability necessary for the successful performance of the duties assigned to the position. The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.
Syva Toxicology Sales Specialist - West Varian Medical Systems IncSyva Toxicology Sales Specialist - WestSan Carlos, CA$85,600–$117,700 / yearIt is Siemens Healthineers' policy to comply fully and completely with all United States export control laws and regulations, including those implemented by the Department of Commerce through the Export Administration Regulations (EAR), by the Department of State through the International Traffic in Arms Regulations (ITAR), and by the Treasury Department through the Office of Foreign Assets Control (OFAC) sanctions regulations.". Call on a variety of specialty accounts, including toxicology laboratories, reference labs, criminal justice labs, drug court programs, industrial testing sites, drug treatment organizations, and other entities performing DAU testing.
Toxicology Management Specialist (Madera, CA) UCSF Medical CenterToxicology Management Specialist (Madera, CA)San Francisco, CAPost graduate or clinical pharmacy residency or fellowship trainingAAPCC Certification as a Specialist in Poison Information or as a Diplomate of the American Board of Applied ToxicologyInvolvement in scholarly activitiesMultilingualPrior emergency medicine or critical care clinical pharmacy experienceExperience with study design, study data analysis, and manuscript preparationFormal teaching experience of clinical learners. Minimum of 2 years of experience in clinically-oriented pharmacy practice OR 2 years prior Poison Control Center experience or an equivalent combination of education and experience; and knowledge and ability necessary for the successful performance of the duties assigned to the position.
Associate Director, Toxicology Protagonist Therapeutics IncAssociate Director, ToxicologyNewark, CA$185,000–$205,000 / yearThe Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs. The base pay range for this position at commencement of employment is expected to be between $185K and $205K / year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
Toxicologist Inductive Bio IncToxicologistSan Francisco, CALocationNew York City, San Francisco, or BostonEmployment TypeFull timeLocation TypeHybridDepartmentScienceOverviewApplicationAt Inductive Bio we're tackling the challenge of making drug discovery more efficient. In this role, you will help shape our scientific offering, ensure that our models are rigorously validated, and guide us toward solutions that have meaningful impact in real-world drug discovery programs.
Senior Scientist II Occupational & Environmental Toxicologist AbbVie IncSenior Scientist II Occupational & Environmental ToxicologistSouth San Francisco, CAScientist II Qualifications: Bachelor's Degree in toxicology or related discipline and typically 12 years of experience OR Master's Degree in toxicology or related discipline and typically 10 years of experience OR PhD in toxicology or related discipline and typically 4 years of experience. This includes toxicology support for extractables and leachables, health-based exposure limits (HBELs) including permitted daily exposure limits (PDEs) and occupational exposure limits (OELs), environmental risk assessments (ERA), and other contaminants.
Scientist LanceSoft IncScientistFremont, CAFull timeProtocol Development: Author robust study protocols, develop data analysis/calculation worksheets, and execute benchtop laboratory testing in strict accordance with approved protocols. The generation of these experimental results will directly support the compilation of technical performance chapters for regulatory dossiers, ensuring compliance with the European Union's In Vitro Diagnostic Regulation (IVDR).
Senior Scientist, Analytical Sciences ORIC Pharmaceuticals IncSenior Scientist, Analytical SciencesSouth San Francisco, CA$150,000–$180,000 / yearORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Create and execute strategic plans for projects, both internally and externally, ensuring product requirements are designed and delivered appropriately and in a timely manner for all the stakeholders and customers at all stages of drug development - from discovery through preclinical to clinical and commercial.
Senior Specialist, Data Science Merck & Co IncSenior Specialist, Data ScienceSan Francisco, CA$129,000–$203,100 / yearThe successful candidate will lead cross-functional projects, deliver production-grade models and agentic systems, and help establish governance and MLOps practices that ensure reproducibility, transparency, and ethical AI use in preclinical research. Hands-on experience with large language models and agentic AI frameworks (fine-tuning, prompt engineering, multi-agent orchestration, tool use, and API-based production orchestration) required.
Computational Scientist (Biology) AxiomComputational Scientist (Biology)San Francisco, Californiali>Analyze high-content imaging and transcriptomic data from primary human hepatocytes and multicellular hepatic systems, including phenotypes related to mitochondrial dysfunction, cholestasis, lipid accumulation, lysosomal stress, ER stress, cytotoxicity, and cellular morphology. You will analyze some of the world’s largest multimodal toxicity datasets, discover biological signals that explain why molecules are safe or toxic, and help turn those discoveries into models used by leading pharma teams to make real drug development decisions.
Head of Translational Biology Earli IncHead of Translational BiologyRedwood City, CAp>• Oversee and manage the Translational Biology group at Earli to support the growth and expansion of the team • Proactively foster the growth of team members and identify opportunities for staff to develop into top-tier, independent pharmacology team members • Design safety and toxicity preclinical studies to support entry of Earli compounds • Be the key external stakeholder to select and oversee CROs to conduct GLP safety and toxicology studies • Help lead strategic planning and oversight of internal and external efforts to assess efficacy and safety testing of Earli's compounds for therapeutic applications across multiple pre-clinical in vivo models • Ensure the production of high-quality technical reports including statistical analyses and data integrity review to support regulatory submissions • Present key findings at internal and external meetings. The successful candidate will have a proven track record of successfully initiating and managing pharmacology and translational science projects across oncology indications from Discovery through IND enabling studies.
Computational Scientist (Medicinal Chemistry) AxiomComputational Scientist (Medicinal Chemistry)San Francisco, CaliforniaWe are looking for a computational scientist with deep medicinal chemistry judgment: someone who can reason across structure, potency, ADME, exposure, toxicity, and mechanism; work directly with world-class drug hunters; and help build AI systems that improve real drug discovery decisions. Influence active drug programs by helping teams understand whether toxicity risk is driven by exposure, potency, off-target biology, reactive metabolites, transporters, mitochondrial liability, cholestasis, immune mechanisms, or other drivers.
Senior Dir, In-Vivo & Non-Clinical Pharmacology Bristol-Myers Squibb CoSenior Dir, In-Vivo & Non-Clinical PharmacologyBrisbane, CA$252,640–$306,137 / yearThis leader will partner deeply with Research leadership and the Pharmacology, DMPK, Toxicology, and Translational Science units to deliver the applications, workflow capabilities, AI, and supporting data flows that enable non-clinical decisions across in-vivo biology, DMPK, ADME, non-clinical safety, toxicology, and bioanalytical science. Non-clinical pharmacology generates the evidence that determines which candidates enter humans, and this role matters now because scientists need better integrated applications, AI, and workflows to generate, interpret, and act on that evidence with greater speed and confidence.
Senior Scientist - siRNA Off-Target Analysis Amgen IncSenior Scientist - siRNA Off-Target AnalysisSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will apply expertise in transcriptomics, computational biology, data visualization, and mechanistic interpretation to design and execute off-target assessments for siRNA experiments, and deliver weight-of-evidence reports and regulatory draft reports.
Associate Director, Translational Science Star TherapeuticsAssociate Director, Translational ScienceSouth San Francisco, CA$156,000–$195,000As an Associate Director, the candidate is expected to represent translational sciences as a translational medicine lead for clinical studies and work closely with the clinical development team members including bioanalysis, clinical operations, regulatory affairs, quality, medical writing, safety, clinical research and clinical leadership. As part of the collaborative research team role, the candidate is expected to work with individuals across research and translational research groups, including discovery research, drug development and protein sciences, preclinical bioanalysis and other junior staff within translational research organization.
Senior/Principal AI/ML Computational Scientist Genentech IncSenior/Principal AI/ML Computational ScientistSouth San Francisco, CA$156,200–$290,200 / yearWho You Are: PhD in biomedical engineering, bioengineering, computer science, computational biology, bioinformatics, data science, statistics, computer vision, image analysis, or a related quantitative discipline; Senior Scientist level (0-2 years) Principal Scientist (3+ years of experience). Our work focuses on extracting quantitative, reproducible, and biologically meaningful information from digital histopathology images and related imaging datasets to support preclinical safety assessment, mechanistic investigation, and translational research.
Principal Environmental Risk Assessor Geosyntec Consultants, Inc.Principal Environmental Risk AssessorOakland, CaliforniaThe role emphasizes technical leadership on CERCLA, RCRA, PFAS, sediment, vapor intrusion, and risk-based cleanup projects; trusted advisory relationships with clients and regulators; and collaboration across multidisciplinary teams. This position is ideal for an accomplished leader in toxicology, ecological risk assessment (ERA), and human health risk assessment (HHRA) who can help grow and lead complex site investigation, remediation, and redevelopment projects across industrial, energy, and public-sector markets.