Principal/Senior Principal Validation Engineer Genentech IncPrincipal/Senior Principal Validation EngineerHolly Springs, NC$95,000–$176,000 / yearThe Opportunity: Reporting to the Head of Validation, the Principal/Senior Principal Validation Engineer serves as the primary technical expert for establishing and executing validation strategies across high-speed pre-filled syringe (PFS) assembly, labeling, traying, automated cartoning, case packing, and associated facilities and utilities. In this strategic, high-impact role, you will define, execute, and maintain the lifecycle validation strategy (IQ/OQ/PQ/PPQ as applicable) for combination product assembly and packaging lines, supporting facilities, and utilities-particularly in support of a new greenfield facility setup.
Senior Master Manufacturing Technician, Filling Operations Genentech IncSenior Master Manufacturing Technician, Filling OperationsHolly Springs, NC$61,600–$114,400 / yearIn partnership with the Engineering and the start-up project (user) team, you will partner and collaborate with our partner organizations (Engineering and MSAT, Quality, Supply Chain, Technical Development, Regulatory, CMO, Strategy) to provide input as the end-user for activities related to design and start-up a new Drug Product Fill and Finish facility. This plant meets today's demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes.
Principal Data Scientist - RDT Applied AI GenentechPrincipal Data Scientist - RDT Applied AIRather than owning the day-to-day delivery of a single project, you will operate in a highly dynamic, cross-departmental landscape—acting as a strategic consultant across a broad portfolio of initiatives to guide multiple teams in transforming complex data into the predictive and generative engines that power our next generation of healthcare innovations. You will balance technical advisory with strategic leadership—shaping technical roadmaps, optimizing deployment strategies, and mentoring talent, all while advising senior business leaders on the art of the possible with AI in a regulated pharma environment.
Quality Excellence Lead GenentechQuality Excellence LeadProven Quality Systems expertise: Background in quality systems management, ownership, and strategy within regulated health/pharma environments (e.g., Good Clinical Practice [GCP], Good Pharmacovigilance Practices [GVP], Medical Device Regulation [MDR], Software as a Medical Device [SaMD], or Risk-Based Quality Management [RBQM]). Cultivate a high-impact knowledge network: Implement and champion knowledge management practices across Pharma Development Quality to foster seamless learning and organizational growth.
Vice President, Immunology Research - Genentech Research & Early Development GenentechVice President, Immunology Research - Genentech Research & Early DevelopmentAdvancing functional genomics efforts in collaboration with our Translational Genomics and Proteomics Center through interrogation of normal and human disease tissues and conducting large scale genomic and small molecule screens to identify novel therapeutic targets and leads, respectively. Collaborating with the Translational Medicine organization to deepen insights into human disease heterogeneity, enabling the discovery and development of biomarkers to guide precision medicines and identification of novel targets/pathways through ‘reverse translation’ from the clinic.
Site Head, Kentucky Distribution Center (Sr. Director) Genentech IncSite Head, Kentucky Distribution Center (Sr. Director)Louisville, KY$153,000–$284,200 / yearLeadership & Industry Experience: Proven track record as a site head in distribution, warehouse, or manufacturing operations within the pharmaceutical, biotech, or healthcare distribution space (15+ years of total supply chain/distribution experience preferred, with 10-12+ years of relevant leadership experience, including cold-chain management). Director), you are directly accountable for the safe, cost-effective, and cGMP-compliant operation of our primary US distribution center, driving strategic vision and network alignment while inspiring a high-performing organization through servant leadership, personal transformation, and clear vision to optimize the contributions of all employees.
Postdoctoral Fellow, Immunology Discovery, Kapadia Lab GenentechPostdoctoral Fellow, Immunology Discovery, Kapadia LabConsistent track record of independently conducting laboratory experiments and advancing at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal. We are seeking a highly motivated, independent scientist to spearhead innovative research to identify novel biology in chronic inflammatory lung diseases, such as COPD, bronchiectasis, pulmonary fibrosis, and inflammatory airway disorders.
Field Medical Insights Director GenentechField Medical Insights DirectorBy translating complex healthcare dynamics and advanced data assets into actionable strategic direction, the team empowers senior leadership to make confident, forward-looking decisions in a rapidly evolving market. Strategic Leadership: Contribute to long-range business planning, advocate for continuous capability improvements, and champion enterprise-wide initiatives that link individual activities to tangible business and patient value.
Executive Director, Targeting, Optimization, & Measurement Analytical Suite GenentechExecutive Director, Targeting, Optimization, & Measurement Analytical SuiteAs a strategic commercial analytics leader, the Executive Director of Targeting, Optimization, & Measurement in Insights & Analytics drives the vision, design, and execution of scalable advanced analytics capabilities across the organization—such as Next Best Action, Customer Orchestration, resource optimization, and measurement. Measurement: Build measurement frameworks for analytics and AI solutions, including success metrics, test-and-learn design, adoption tracking, performance monitoring, and outcome measurement to quantify business, scientific, operational, and patient impact.
Principal Quality Lead GenentechPrincipal Quality LeadHigh degree of experience, competency, and proven track record leading multiple complex audit types in multiple GxP/CSV areas; Experience hosting, managing and supporting regulatory authority inspections; Strong digital and data literacy. Proven ability to influence and negotiate effective solutions within PDQ, PD, and/or industry through leading change and driving for results; Strong understanding of PDQ business and functional group operations; Proven ability to assimilate new and emerging compliance information or trends and translate into impact for PDQ.
Enterprise Architect - Pharma Commercial GenentechEnterprise Architect - Pharma CommercialPartner with Business and Roche Digital Technology (RDT) leadership to align global and regional business priorities with multi-year technology roadmaps and target-state architectures. Guide investment decisions alongside Portfolio Management by evaluating strategic impacts, maximizing platform reuse, and managing technical debt to optimize total cost of ownership (TCO).
Scientist 3- Translational Medicine (Multiple Sclerosis & TR focused) GenentechScientist 3- Translational Medicine (Multiple Sclerosis & TR focused)Analyze and interpret high-dimensional datasets from clinical samples, including single-cell RNA-seq, CITE-seq, bulk RNA-seq, spatial transcriptomics, and/or proteomics, to generate translational insights that support clinical development. This role sits at the intersection of clinical development and translational science — the ideal candidate is comfortable working with clinical biospecimens, interpreting high-dimensional datasets, and contributing findings that directly inform clinical trial design and molecule progression.
Enterprise Architect - Pharma Commercial Genentech IncEnterprise Architect - Pharma CommercialSouth San Francisco, CA$170,800–$317,200 / yearPartner with Business and Roche Digital Technology (RDT) leadership to align global and regional business priorities with multi-year technology roadmaps and target-state architectures. Guide investment decisions alongside Portfolio Management by evaluating strategic impacts, maximizing platform reuse, and managing technical debt to optimize total cost of ownership (TCO).
Scientist 3- Translational Medicine (Multiple Sclerosis & TR focused) Genentech IncScientist 3- Translational Medicine (Multiple Sclerosis & TR focused)South San Francisco, CA$100,400–$186,400 / yearAnalyze and interpret high-dimensional datasets from clinical samples, including single-cell RNA-seq, CITE-seq, bulk RNA-seq, spatial transcriptomics, and/or proteomics, to generate translational insights that support clinical development. This role sits at the intersection of clinical development and translational science - the ideal candidate is comfortable working with clinical biospecimens, interpreting high-dimensional datasets, and contributing findings that directly inform clinical trial design and molecule progression.
MES Change Specialist GenentechMES Change SpecialistHillsboro, OregonAs a key member of the Process and Compliance team, you will perform a wide variety of tasks and operations that are required to design, build, test, validate, and maintain pharmaceutical production in a state-of-the-art, highly-automated production and packaging facility. The MES Change Specialist works cross-functionally with manufacturing, P&C, ITOT, Master data, and many other departments to ensure the efficient construction and effective functionality of our electronic documentation for operations across HTO.
MES Change Specialist Genentech IncMES Change SpecialistHillsboro, OR$79,000–$146,000 / yearThe Opportunity: As a key member of the Process and Compliance team, you will perform a wide variety of tasks and operations that are required to design, build, test, validate, and maintain pharmaceutical production in a state-of-the-art, highly-automated production and packaging facility. The MES Change Specialist works cross-functionally with manufacturing, P&C, ITOT, Master data, and many other departments to ensure the efficient construction and effective functionality of our electronic documentation for operations across HTO.
Director, Safety, Security, Health, and Environment GenentechDirector, Safety, Security, Health, and EnvironmentHolly Springs, North CarolinaThis plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes. As the Head of Site Safety, Security, Health and Environment, you will have overall responsibility for ensuring a safe, compliant and sustainable operation of our campus, including buildings, grounds, manufacturing processes, and utilities.
New2027 Spring Intern - Cell Culture and Bioprocess Operations (CCBO) Genentech Inc2027 Spring Intern - Cell Culture and Bioprocess Operations (CCBO)South San Francisco, CA$26–$47 / hourWe in Cell Culture and Bioprocess Operations develop the cell lines used to make our products, improve the process of cell line development, manufacture GMP cell banks to support clinical and commercial drug substance production, and develop the fermentation and cell culture processes to support pre-clinical and clinical development through Phase III. Required Majors: Chemical Engineering, Molecular Biology, Genetics, Bioengineering, Biomedical Engineering, Mechanical Engineering, Bioengineering, Pharmaceutical Engineering, Chemistry, Biology, Microbiology, Biophysics, or related disciplines.
2027 Spring Intern - Product Technical Development - Digital Sciences Focus Genentech Inc2027 Spring Intern - Product Technical Development - Digital Sciences FocusSouth San Francisco, CA$28–$52 / hourPharmaceutical Technical Development (PTD) develops, delivers, and supports robust, cost-effective production methods and technologies for innovative therapeutics to meet the needs of Genentech's Research, Development, Commercial, and Product Operations groups. As a Digital Sciences intern, you can expect to leverage your programming skills to contribute to digital projects, such as full-stack software applications and data science models, that will make an impact across the entire PTD organization.
Senior Strategy Manager, Customer Segment Strategy (Health Systems) Genentech IncSenior Strategy Manager, Customer Segment Strategy (Health Systems)Washington, DC$161,000–$299,000 / yearThis role bridges the gap between CE Account Teams, Squads, and Pricing, Contracting, and Distribution (PCD) leads, ensuring a customer-centric approach that directly impacts Genentech's P&L and patient access. 5+ years of relevant work experience in the pharmaceutical industry, such as: payer or contracting strategy, account management, consulting, market analysis, health economics, distribution strategy, and/or managed care finance.