Senior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT) GenentechSenior/Principal Machine Learning Scientist, Perturbation Biology, AI Biology & Translation (AIBT)The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. We are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology group in the Department of AI for Biology & Translation (AIBT) in Genentech Research and Early Development (gRED).
Data Management TA Lead, Early Development GenentechData Management TA Lead, Early DevelopmentEarly Development Biometrics is also home to Methods Collaboration & Outreach (MCO), which enables the most impactful use of quantitative methodology across PDD through internal consultation, external collaboration, and continuous capability building; and Visual Analytics, which creates and maintains interactive dashboards that drive high-quality Medical Data Review (MDR) and safety signal detection, aligned with Risk-Based Quality Management (RBQM) principles and Critical-to-Quality (CtQ) endpoints. As trusted partners in early development, we design efficient and innovative clinical trials, apply rigorous statistical methods, and implement high-quality programming and analytical solutions to accelerate timelines, de-risk development, and increase the probability of technical success.
Principal Product Leader, Therapeutics Discovery Genentech IncPrincipal Product Leader, Therapeutics DiscoverySouth San Francisco, CA$148,600–$276,000 / yearThe new Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Reporting to the Domain Head for Therapeutics Discovery, this Principal Product Leader will play a key role in defining and executing the strategy for a family of products that are critical for molecule design, making, testing, learning, and/or data lifecyclein drug discovery.
Postdoctoral Fellow, Cell Therapy/Immunology, Ng and Kim Labs Genentech IncPostdoctoral Fellow, Cell Therapy/Immunology, Ng and Kim LabsSouth San Francisco, CA$100,000–$106,500 / yearA Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Andrew Ng in the Department of Cell Therapy and co-mentored by Dr. Hye-Jung Kim in the Department of Immunology Discovery at Genentech. To participate in the Genentech post-doctoral training program, which offers outstanding training and mentorship, opportunities to present work internally and externally, career development support, and exposure to an environment focused on drug development and breakthrough discoveries.
Senior Principal Statistician GenentechSenior Principal StatisticianBoston, MassachusettsAs trusted analytical partners in end-to-end drug development, Biostatistics leverages data to drive scientifically rigorous programmatic decisions across Roche’s Development portfolio; Biostatistics designs robust trials and analysis plans that increase the probability of technical success, accelerating timelines to advance Roche’s clinical pipeline and promote regulatory success — ultimately bringing medicines to our patients faster. This role ensures the scientific rigor and regulatory compliance of the study by contributing to protocol development, authoring statistical analysis plans, performing or overseeing data analyses, and supporting the interpretation and communication of results.
Principal ADS Program Lead GenentechPrincipal ADS Program LeadBoston, MassachusettsIn addition to overseeing day-to-day delivery, the Analytical Data Science Program Lead is accountable for a broad range of analytical outputs including but not limited to: exploratory analyses, application development and dynamic visualization to enable ongoing data review and scientific insights generation. This role leads a team of highly skilled programmers and junior leaders, ensuring the delivery of high-quality, regulatory-compliant analytical outputs that support key development milestones and health authority submissions.
Senior / Principal Machine Learning Scientist, Scientific Reasoning Models, AI for Drug Discovery GenentechSenior / Principal Machine Learning Scientist, Scientific Reasoning Models, AI for Drug DiscoveryNew York City, New YorkThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. In this role, you will: Technical Leadership & Strategy: Lead the design and evolution of scientific reasoning systems, setting technical direction for model architectures, training strategies, and evaluation methodologies.
Senior Principal Statistician, Early Development (Director Level) GenentechSenior Principal Statistician, Early Development (Director Level)Early Development Biometrics is also home to the Statistical Methodology group, which enables the most impactful use of quantitative methodology across PDD through internal consultation, external collaboration, and continuous capability building; and Visual Analytics, which creates and maintains interactive dashboards that drive high-quality Medical Data Review (MDR) and safety signal detection, aligned with Risk-Based Quality Management (RBQM) principles and Critical-to-Quality (CtQ) endpoints. As trusted partners in early development, we design efficient and innovative clinical trials, apply rigorous statistical methods, and implement high-quality programming and analytical solutions to accelerate timelines, de-risk development, and increase the probability of technical success.
Principal Quality Lead GenentechPrincipal Quality LeadProven ability to influence and negotiate effective solutions within PDQ, PD, and/or industry through leading change and driving for results; Strong understanding of PDQ business and functional group operations; Proven ability to assimilate new and emerging compliance information or trends and translate into impact for PDQ. High degree of experience, competency, and proven track record leading multiple complex audit types in multiple GxP/CSV areas; Experience supporting regulatory authority inspections; Strong digital and data literacy.
Postdoctoral Fellow - Discovery Oncology, West Lab Genentech IncPostdoctoral Fellow - Discovery Oncology, West LabSouth San Francisco, CA$100,000–$106,500 / yearTo participate in the Genentech post-doctoral training program, which offers outstanding training and mentorship, opportunities to present work internally and externally, career development support, and exposure to an environment focused on drug development and breakthrough discoveries. A Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Nathaniel West in the Department of Discovery Oncology at Genentech.
Senior Plant Engineer, Dixon - Site Services GenentechSenior Plant Engineer, Dixon - Site ServicesDixon, CaliforniaIn this strategic role, you won't just maintain systems—you'll be the principal technical authority driving capital projects from conception through commissioning, leading reliability initiatives that prevent costly downtime, and ensuring our facilities operate at peak efficiency and safety. This is a unique opportunity to combine hands-on technical expertise with strategic leadership, working autonomously as a trusted subject matter expert who directly influences multi-million-dollar investments and operational decisions.
Head of Product Biometrics GenentechHead of Product BiometricsBoston, Massachusetts10+ years in Product Management or Business Analysis, with at least 4 years in Pharma/Biotech Biometrics domain and 4+ years in a leadership role managing interdisciplinary teamsinterdisciplinarytechnical teams. The team delivers the technology solutions required for statistical analysis, aggregation, and data preparation for regulatory reporting of primary clinical trial data, but also for driving the acquisition and curation of data from Case Report Forms (CRFs) and Real-World Data (RWD).
Master Manufacturing Techncian, Packaging GenentechMaster Manufacturing Techncian, PackagingHolly Springs, North CarolinaIn partnership with the Engineering and the start-up project (user) team, you will partner and collaborate with our partner organizations (Engineering and MSAT, Quality, Supply Chain, Technical Development, Regulatory, CMO, Strategy) to provide input as the end-user for activities related to design and start-up a new Drug Product Fill and Finish facility. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes.
Principal Scientist, Peptide Therapeutics GenentechPrincipal Scientist, Peptide TherapeuticsSynthetic Mastery: Utilize expert-level skills in solid-phase peptide synthesis, solution-phase organic chemistry, and specialized macrocyclization or ligation strategies. In this lab-based leadership role, you will combine hands-on synthetic expertise with strategic oversight, driving the discovery and optimization of peptide therapeutics across the full development lifecycle.
NewSenior Instrumentation Technician GenentechSenior Instrumentation TechnicianHigh School Diploma or GED and one of the following: Completion of an Instrumentation or Electronics Engineering (2-year) curriculum at a technical school with three years’ experience as an instrument or electronics technician. Ability to interact and communicate appropriately with Manufacturing, Quality, Technology, Engineering, and other departments to ensure satisfactory performance of instruments and systems.
Principal Product Leader, Therapeutics Discovery GenentechPrincipal Product Leader, Therapeutics DiscoveryThe new Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Reporting to the Domain Head for Therapeutics Discovery, this Principal Product Leader will play a key role in defining and executing the strategy for a family of products that are critical for molecule design, making, testing, learning, and/or data lifecyclein drug discovery.
Principal/Senior Principal Process Engineer, Aseptic Operations/Filling GenentechPrincipal/Senior Principal Process Engineer, Aseptic Operations/FillingHillsboro, OregonGenentech's Hillsboro Technical Operations (HTO), located in Hillsboro Oregon, is Drug Product manufacturing (Component Prep & Compounding, Liquid/Lyophilized Filling, Automated/Manual Inspection, Packaging/Finished Products and Distribution). You hold a BS/MS in Engineering, Pharmaceutical Sciences, or a related eld, and have the minimum years of relevant experience (Principal Engineer = minimum 8, Senior Principal Engineer = minimum 12).
Global Head of Biostatistics GenentechGlobal Head of BiostatisticsBoston, MassachusettsAs the Global Head of Biostatistics, you will provide strategic leadership and oversight across all Therapeutic Area (TA)-aligned Biostatistics teams, ensuring a cohesive and high-performing Biostatistics function that drives excellence in service of our strategy through study design, data analysis, and insights generation. Act as the primary liaison between the Biostatistics function and key stakeholders across Clinical, Regulatory, and Data Science teams to drive alignment and shape outcomes for shared objectives; connect key stakeholders with therapeutic area Biostatistics Leaders as nuanced questions arise.
Principal/Senior Principal Process Engineer, Aseptic Operations/Filling Genentech IncPrincipal/Senior Principal Process Engineer, Aseptic Operations/FillingHillsboro, OR$114,380–$212,420 / yearGenentech's Hillsboro Technical Operations (HTO), located in Hillsboro Oregon, is Drug Product manufacturing (Component Prep & Compounding, Liquid/Lyophilized Filling, Automated/Manual Inspection, Packaging/Finished Products and Distribution). Who are you: You hold a BS/MS in Engineering, Pharmaceutical Sciences, or a related eld, and have the minimum years of relevant experience (Principal Engineer = minimum 8, Senior Principal Engineer = minimum 12).
Senior Plant Engineer, Dixon - Site Services Genentech IncSenior Plant Engineer, Dixon - Site ServicesSouth San Francisco, CA$109,500–$203,300 / yearIn this strategic role, you won't just maintain systems-you'll be the principal technical authority driving capital projects from conception through commissioning, leading reliability initiatives that prevent costly downtime, and ensuring our facilities operate at peak efficiency and safety. This is a unique opportunity to combine hands-on technical expertise with strategic leadership, working autonomously as a trusted subject matter expert who directly influences multi-million-dollar investments and operational decisions.