Machine Learning Scientist/Senior Machine Learning Scientist - Synthesis Planning and Optimization, AI for Drug Discovery GenentechMachine Learning Scientist/Senior Machine Learning Scientist - Synthesis Planning and Optimization, AI for Drug DiscoverySan Francisco, CaliforniaYou hold a PhD or equivalent research depth in machine learning, computational chemistry, chemical engineering or a related quantitative field such as physics or statistics, with up to 2 years of industry research experience (Scientist) or 2+ years of industry research experience (Senior Scientist). The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
Vice President, Head of Site Services Operations GenentechVice President, Head of Site Services OperationsAs a member of the Site Services Leadership Group reporting to the Senior Vice President of Site Services, you will serve as a trusted advisor to the Genentech Executive Committee, balancing operational efficiency with innovation to enable cutting-edge research, development, manufacturing, and commercial activities that advance our mission to provide life-saving medicine. Develop and execute comprehensive strategies for operational continuity and excellence throughout major campus redevelopment initiatives, including demolition and reconstruction, while scaling site services across regional locations and integrating satellite campuses through Integrated Facilities Management (IFM) models.
Software Development Engineer/Senior Software Development Engineer, Agentic Systems, AI for Drug Discovery GenentechSoftware Development Engineer/Senior Software Development Engineer, Agentic Systems, AI for Drug DiscoveryNew York City, New YorkFor the Software Engineer level, you have a bachelor’s or master’s degree in Computer Science, Software Engineering, or a related technical field, or equivalent practical experience, and 3+ years of professional software engineering experience and for the Senior Software Engineer level, you have a bachelor’s or master’s degree in Computer Science, Software Engineering, or a related technical field, or equivalent practical experience, and 5+ years of professional software engineering experience. The Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and life-changing medicines for patients worldwide.
Neuro Rare Diseases Account Manager (NRD-AM) - California South Ecosystem GenentechNeuro Rare Diseases Account Manager (NRD-AM) - California South EcosystemCaliforniaServe as the primary point of contact for healthcare providers, specialty pharmacies, patients/caregivers, and patient advocacy team members, addressing their clinical, educational, and business needs to support improved patient outcomes and quality of care. Collaborates with Partnership and Access Liaison (PAL) to develop comprehensive local geography business plans, while working proactively with PAL and Case Manager roles to ensure a positive end-to-end experience for HCPs, patients, and caregivers.
Enterprise Architect - Pharma Commercial GenentechEnterprise Architect - Pharma CommercialPartner with Business and Roche Digital Technology (RDT) leadership to align global and regional business priorities with multi-year technology roadmaps and target-state architectures. Guide investment decisions alongside Portfolio Management by evaluating strategic impacts, maximizing platform reuse, and managing technical debt to optimize total cost of ownership (TCO).
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) GenentechSenior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Control Systems Lead (Automation Manager - Holly Springs) GenentechControl Systems Lead (Automation Manager - Holly Springs)Holly Springs, North CarolinaControl Systems Lead/ Automation Manager (Department: ITOT/Automation Engineering - Leadership Role) will be Responsible for providing automation ad instrumentation and controls engineering capabilities and experience to the ITOT / Automation Engineering Group including generating qualification protocols and maintaining the validated state of systems and processes. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes.
Senior Principal Statistician, Early Development (Director Level) GenentechSenior Principal Statistician, Early Development (Director Level)$171,600–$318,600 / yearEarly Development Biometrics is also home to the Statistical Methodology group, which enables the most impactful use of quantitative methodology across PDD through internal consultation, external collaboration, and continuous capability building; and Visual Analytics, which creates and maintains interactive dashboards that drive high-quality Medical Data Review (MDR) and safety signal detection, aligned with Risk-Based Quality Management (RBQM) principles and Critical-to-Quality (CtQ) endpoints. As trusted partners in early development, we design efficient and innovative clinical trials, apply rigorous statistical methods, and implement high-quality programming and analytical solutions to accelerate timelines, de-risk development, and increase the probability of technical success.
Principal Quality Lead GenentechPrincipal Quality LeadProven ability to influence and negotiate effective solutions within PDQ, PD, and/or industry through leading change and driving for results; Strong understanding of PDQ business and functional group operations; Proven ability to assimilate new and emerging compliance information or trends and translate into impact for PDQ. High degree of experience, competency, and proven track record leading multiple complex audit types in multiple GxP/CSV areas; Experience supporting regulatory authority inspections; Strong digital and data literacy.
Direct Materials Regulatory Filings Principal Expert GenentechDirect Materials Regulatory Filings Principal ExpertOceanside, CaliforniaComplex Problem Solving: Applies data-driven knowledge to the most complex regulatory challenges, particularly in high-risk areas such as virus-risk, BSE/TSE, and biological-derived material compliance. Stakeholders Influence: Drives modernization and technology innovation by influencing stakeholders (including senior stakeholders) across PTD, PTM, PTT, PTC and PTQ to drive successful program implementation.
Principal Project Controls Engineer GenentechPrincipal Project Controls EngineerHillsboro, Oregon$119,000–$222,000 / yearCredentialed Controls Professional: You hold a Bachelor's degree in Engineering, Economics, or Business Administration, backed by a professional qualification from PMI, RICS, or AACEi (or equivalent), with a minimum of 8 years (6 with a Masters) of hands-on experience in Project Controls roles such as Cost Engineer or Quantity Surveyor. Skilled Matrix Collaborator: You demonstrate exceptional interpersonal and communication skills with the ability to influence and lead across matrixed environments, engaging effectively with Project Managers, Finance partners, procurement teams, contractors, and executive leadership.
Machine Learning Scientist, Scientific Reasoning Models, AI for Drug Discovery GenentechMachine Learning Scientist, Scientific Reasoning Models, AI for Drug DiscoveryNew York City, New YorkThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. LLM Expertise: Experience developing and training large-scale machine learning models, including post-training techniques to enhance domain knowledge, reasoning capabilities, and model alignment.
NewPrincipal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD) Genentech IncPrincipal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD)South San Francisco, CA$201,300–$373,800 / yearYou would be stepping into a role with outsized impact: driving portfolio applications of advanced ML models directly to gRED projects, serving as a trusted technical advisor to gRED leadership, and building a team of computational scientists who collectively raise the bar for what's possible in large molecule design. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
Senior Thought Leader Liaison - Neuroimmunology Genentech IncSenior Thought Leader Liaison - NeuroimmunologyIndianapolis, IN$162,500–$301,700 / yearThe Opportunity: The Senior TLL role at Genentech acts as the lead Commercial enterprise bridge to National & Regional Therapeutic Area Experts (TAEs) across Therapeutic Areas (TAs), operating as a proactive strategic partner who shapes markets and converts TAE influence into measurable results. Actively participate in core Marketing and TLL sub-teams (e.g., ad boards, insights, congresses) and lead cross-functional alignment across Marketing, Medical, CE, Compliance, Legal, and Global teams to focus TLL efforts on key TA and launch needs.
NewPrincipal Scientist, SOP & Workflow Automation Champion, AI for Drug Discovery (AIDD) Genentech IncPrincipal Scientist, SOP & Workflow Automation Champion, AI for Drug Discovery (AIDD)South San Francisco, CA$201,300–$373,800 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. We have developed novel machine learning capabilities for large molecule discovery, but translating those capabilities into scalable, operationalized workflows at the organizational level requires both scientific credibility and strategic engineering acumen.
NewPX Solutions Lead Genentech IncPX Solutions LeadSouth San Francisco, CA$161,100–$299,000 / yearThe CMG Patient Strategy aims to create a holistic, cross-functional approach to deliver a best-in-class patient experience that aligns with the portfolio, technology tools, and consumer-driven patient expectations in a rapidly evolving business landscape. Partner cross-functionally with DDA, RDT, PAA Activation & Capabilities Enablement, Legal, HCO, US Medical, CPO, CE and external vendor partners to ensure technical feasibility, regulatory alignment, and seamless execution.
Sr. PX Business Partner (Foundational Products/Influenza/CVRM) GenentechSr. PX Business Partner (Foundational Products/Influenza/CVRM)The CMG Patient Strategy aims to create a holistic, cross-functional approach to deliver a best-in-class patient experience that aligns with the portfolio, technology tools, and consumer-driven patient expectations in a rapidly evolving business landscape. In this role, you will: Serve as the primary point of contact and trusted advisor within PX for high-complexity TAs, embedding within relevant Squads to capture, clarify, and document TA-specific patient experience needs across the product lifecycle.
Commercial Affordability Principal Project Manager GenentechCommercial Affordability Principal Project ManagerAs the Commercial Affordability Principal Project Manager, you will serve as a key cross-portfolio subject matter expert driving the end-to-end operational execution of Genentech’s commercial affordability programs (including Co-pay, Bridge/Starter, Coupon other patient free goods programs). The CMG Patient Strategy aims to create a holistic, cross-functional approach to deliver a best-in-class patient experience that aligns with the portfolio, technology tools, and consumer-driven patient expectations in a rapidly evolving business landscape.
Senior / Principal Machine Learning Scientist, Scientific Reasoning Models, AI for Drug Discovery GenentechSenior / Principal Machine Learning Scientist, Scientific Reasoning Models, AI for Drug DiscoveryNew York City, New YorkThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. In this role, you will: Technical Leadership & Strategy: Lead the design and evolution of scientific reasoning systems, setting technical direction for model architectures, training strategies, and evaluation methodologies.
Senior Principal Project Controls Manager GenentechSenior Principal Project Controls ManagerHolly Springs, North CarolinaThe Opportunity: As a Senior Principal Projects Controls Manager, within the capital delivery group, you will be responsible for leading all aspects of project controls on large and/or complex facility/equipment improvement projects within our US manufacturing network as well as potentially at our international sites. Key responsibilities include: Develop and lead the project controls team, motivating them through your strong communication and leadership skills with clear decision-making in cost estimating, scheduling, risk management, resource management, cost management and change management.